PH12015500095A1 - Attenuated swine influenza vaccines and methods of making and use thereof - Google Patents

Attenuated swine influenza vaccines and methods of making and use thereof

Info

Publication number
PH12015500095A1
PH12015500095A1 PH12015500095A PH12015500095A PH12015500095A1 PH 12015500095 A1 PH12015500095 A1 PH 12015500095A1 PH 12015500095 A PH12015500095 A PH 12015500095A PH 12015500095 A PH12015500095 A PH 12015500095A PH 12015500095 A1 PH12015500095 A1 PH 12015500095A1
Authority
PH
Philippines
Prior art keywords
methods
attenuated
swine influenza
making
influenza vaccines
Prior art date
Application number
PH12015500095A
Other languages
English (en)
Other versions
PH12015500095B1 (en
Inventor
Benjamin M Hause
Original Assignee
Merial Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merial Ltd filed Critical Merial Ltd
Publication of PH12015500095B1 publication Critical patent/PH12015500095B1/en
Publication of PH12015500095A1 publication Critical patent/PH12015500095A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0241Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/21Retroviridae, e.g. equine infectious anemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16121Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16161Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PH12015500095A 2012-07-17 2015-01-14 Attenuated swine influenza vaccines and methods of making and use thereof PH12015500095A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261672398P 2012-07-17 2012-07-17
PCT/US2013/050000 WO2014014726A1 (en) 2012-07-17 2013-07-11 Attenuated swine influenza vaccines and methods of making and use thereof

Publications (2)

Publication Number Publication Date
PH12015500095B1 PH12015500095B1 (en) 2015-03-02
PH12015500095A1 true PH12015500095A1 (en) 2015-03-02

Family

ID=48874529

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12015500095A PH12015500095A1 (en) 2012-07-17 2015-01-14 Attenuated swine influenza vaccines and methods of making and use thereof

Country Status (19)

Country Link
US (2) US9216211B2 (enrdf_load_stackoverflow)
EP (1) EP2874656B1 (enrdf_load_stackoverflow)
JP (1) JP6467672B2 (enrdf_load_stackoverflow)
KR (1) KR102027758B1 (enrdf_load_stackoverflow)
CN (1) CN104582725B (enrdf_load_stackoverflow)
AU (2) AU2013290597B2 (enrdf_load_stackoverflow)
BR (1) BR112015001020B1 (enrdf_load_stackoverflow)
CA (1) CA2879228C (enrdf_load_stackoverflow)
DK (1) DK2874656T3 (enrdf_load_stackoverflow)
EA (1) EA033027B1 (enrdf_load_stackoverflow)
ES (1) ES2662022T3 (enrdf_load_stackoverflow)
HU (1) HUE036110T2 (enrdf_load_stackoverflow)
MX (1) MX365880B (enrdf_load_stackoverflow)
MY (1) MY166879A (enrdf_load_stackoverflow)
NZ (2) NZ704188A (enrdf_load_stackoverflow)
PH (1) PH12015500095A1 (enrdf_load_stackoverflow)
PL (1) PL2874656T3 (enrdf_load_stackoverflow)
PT (1) PT2874656T (enrdf_load_stackoverflow)
WO (1) WO2014014726A1 (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ704188A (en) * 2012-07-17 2016-04-29 Merial Inc Attenuated swine influenza vaccines and methods of making and use thereof
KR102166196B1 (ko) * 2015-12-28 2020-10-15 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 M hyo 다가 백신 및 이의 용도
EA201991319A1 (ru) 2016-11-30 2019-11-29 Вакцины аттенуированного свиного гриппа и способы их изготовления и применения
CN106939355A (zh) * 2017-03-01 2017-07-11 苏州系统医学研究所 一种流感病毒弱毒活疫苗毒株的筛选和鉴定方法
CN107064499B (zh) * 2017-03-15 2019-06-18 青岛蔚蓝生物制品有限公司 禽流感病毒np蛋白抗原表位多肽及其胶体金试纸盒
AU2018392799A1 (en) 2017-12-22 2020-05-28 Codagenix, Inc. Recombinant virus with codon-pair deoptimized region and uses thereof for the treatment of cancer
WO2019172982A1 (en) 2018-03-08 2019-09-12 Codagenix Inc. Attenuated flaviviruses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US5585250A (en) 1993-08-20 1996-12-17 The United States Of America As Represented By The Department Of Health & Human Services Dampening of an immunodominant epitope of an antigen for use in plant, animal and human compositions and immunotherapies
DE69733020T2 (de) 1996-10-11 2006-02-16 The Regents Of The University Of California, Oakland Immunostimulierende oligonucleotidekonjugate
US5980912A (en) 1997-03-25 1999-11-09 Zonagen, Inc. Chitosan induced immunopotentiation
CA2526834A1 (en) 2003-05-28 2005-03-31 Wisconsin Alumni Research Foundation Recombinant influenza vectors with a polii promoter and ribozymes
US7871626B2 (en) * 2005-08-04 2011-01-18 St. Jude Children's Research Hospital Modified influenza virus for monitoring and improving vaccine efficiency
WO2008157583A1 (en) * 2007-06-18 2008-12-24 Medimmune, Llc Influenza b viruses having alterations in the hemaglutinin polypeptide
CN102014953A (zh) 2008-02-21 2011-04-13 生物模仿公司 流感免疫原组合物
US20140004149A1 (en) * 2010-01-24 2014-01-02 Biological Mimetics, Inc. Immunogenic Influenza Composition
NZ704188A (en) * 2012-07-17 2016-04-29 Merial Inc Attenuated swine influenza vaccines and methods of making and use thereof

Also Published As

Publication number Publication date
EP2874656A1 (en) 2015-05-27
KR102027758B1 (ko) 2019-10-02
HUE036110T2 (hu) 2018-06-28
AU2016202693A1 (en) 2016-05-19
PL2874656T3 (pl) 2018-04-30
KR20150036685A (ko) 2015-04-07
AU2016202693B2 (en) 2017-11-16
CN104582725B (zh) 2017-06-23
PH12015500095B1 (en) 2015-03-02
BR112015001020B1 (pt) 2022-04-19
US9216211B2 (en) 2015-12-22
EA201500140A1 (ru) 2016-02-29
MX2015000713A (es) 2015-10-12
NZ712713A (en) 2017-05-26
DK2874656T3 (en) 2018-01-15
PT2874656T (pt) 2018-03-09
NZ704188A (en) 2016-04-29
MX365880B (es) 2019-06-18
ES2662022T3 (es) 2018-04-05
JP2015524266A (ja) 2015-08-24
CA2879228A1 (en) 2014-01-23
AU2013290597B2 (en) 2016-02-04
WO2014014726A1 (en) 2014-01-23
EA033027B1 (ru) 2019-08-30
MY166879A (en) 2018-07-24
CN104582725A (zh) 2015-04-29
EP2874656B1 (en) 2017-12-06
US20140023681A1 (en) 2014-01-23
US20160120973A1 (en) 2016-05-05
US9623105B2 (en) 2017-04-18
CA2879228C (en) 2021-07-13
AU2013290597A1 (en) 2015-02-19
JP6467672B2 (ja) 2019-02-13
BR112015001020A2 (enrdf_load_stackoverflow) 2017-08-15
HK1209325A1 (en) 2016-04-01

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