PH12014502283A1 - Antibiotic sensitive bacillus strains having antimicrobial effect against e. coli and clostridium perfringens and having high sporulation capacity - Google Patents

Antibiotic sensitive bacillus strains having antimicrobial effect against e. coli and clostridium perfringens and having high sporulation capacity

Info

Publication number
PH12014502283A1
PH12014502283A1 PH12014502283A PH12014502283A PH12014502283A1 PH 12014502283 A1 PH12014502283 A1 PH 12014502283A1 PH 12014502283 A PH12014502283 A PH 12014502283A PH 12014502283 A PH12014502283 A PH 12014502283A PH 12014502283 A1 PH12014502283 A1 PH 12014502283A1
Authority
PH
Philippines
Prior art keywords
coli
clostridium perfringens
effect against
amyloliquefaciens
antimicrobial effect
Prior art date
Application number
PH12014502283A
Other versions
PH12014502283B1 (en
Inventor
Nielsen Beatrice
Cantor Mette Dines
Stuer-Lauridsen Birgitte
Derkx Patrick
Johansen Eric
Original Assignee
Chr Hansen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chr Hansen As filed Critical Chr Hansen As
Publication of PH12014502283A1 publication Critical patent/PH12014502283A1/en
Publication of PH12014502283B1 publication Critical patent/PH12014502283B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/742Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/16Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
    • A23K10/18Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07Bacillus
    • C12R2001/125Bacillus subtilis ; Hay bacillus; Grass bacillus

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physiology (AREA)
  • Animal Husbandry (AREA)
  • Food Science & Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A Bacillus strain characterized by (i) : sensitivity for ampicillin, vancomycin, gentamicin, kanamycin, streptomycin, erythromycin, clindamycin, tetracycline and chloramphenicol; (ii) antimicrobial activity against E. coli and Clostridium perfringens; and (iii) a sporulation percentage of at least 80 when measured after 2 days of incubation. The invention further relates to a method for selecting such strains. Many of the identified strains according to the invention are of the species Bacillus amyloliquefaciens. Some of the Bacillus amyloliquefaciens were further identified as Bacillus amyloliquefaciens subsp. amyloliquefaciens whereas others were identified as amyloliquefaciens subsp. plantarum. A Bacillus strain of the invention may be used as a feed additive to animal feed where it has a probiotic effect.
PH12014502283A 2012-04-13 2014-10-10 Antibiotic sensitive bacillus strains having antimicrobial effect against e. coli and clostridium perfringens and having high sporulation capacity PH12014502283B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12164087 2012-04-13
PCT/EP2013/057590 WO2013153159A1 (en) 2012-04-13 2013-04-11 Antibiotic sensitive bacillus strains having antimicrobial effect against e. coli and clostridium perfringens and having high sporulation capacity

Publications (2)

Publication Number Publication Date
PH12014502283A1 true PH12014502283A1 (en) 2014-12-15
PH12014502283B1 PH12014502283B1 (en) 2014-12-15

Family

ID=48142761

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12014502283A PH12014502283B1 (en) 2012-04-13 2014-10-10 Antibiotic sensitive bacillus strains having antimicrobial effect against e. coli and clostridium perfringens and having high sporulation capacity

Country Status (17)

Country Link
US (2) US9844573B2 (en)
EP (2) EP3486313A1 (en)
JP (1) JP6212108B2 (en)
KR (1) KR102128560B1 (en)
CN (1) CN104487566B (en)
AU (1) AU2013246850B2 (en)
BR (1) BR112014025119B1 (en)
CA (1) CA2869036C (en)
DK (1) DK2836589T3 (en)
EA (1) EA028359B1 (en)
ES (1) ES2695149T3 (en)
HK (1) HK1201558A1 (en)
MX (1) MX357230B (en)
PH (1) PH12014502283B1 (en)
PL (1) PL2836589T3 (en)
TR (1) TR201815560T4 (en)
WO (1) WO2013153159A1 (en)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103571811B (en) * 2013-10-19 2015-04-22 沅江浣溪沙酶技术有限公司 Xylanase and production method
JP6440463B2 (en) * 2013-11-15 2018-12-19 プリマハム株式会社 Bacillus methylotrophicus with antibacterial action
CN103740607B (en) * 2013-11-28 2015-10-14 中国农业科学院农业资源与农业区划研究所 A kind of mocha husband bacillus and microbiobacterial agent and their application
CN103865839B (en) * 2014-01-03 2017-12-26 青岛东海药业有限公司 A kind of probiotics applied to aquaculture
BR112016026359B1 (en) 2014-05-13 2022-03-22 Microbial Discovery Group, Llc Methods for controlling the harmful environmental effects of manure and for feeding an animal, packaging, feed and drinking water additives, and feed composition
US20170224745A1 (en) * 2014-07-25 2017-08-10 The University Of Queensland Bacillus amyloliquefaciens probiotic compositions, methods of production, and methods of use
EP3200590B1 (en) * 2014-09-30 2020-09-02 Auburn University Use of pectin or pectin-related saccharides to enhance efficacy of plant growth-promoting rhizobacteria (pgpr) strains for promoting growth and health in plants
JP6595761B2 (en) * 2014-12-19 2019-10-23 東亜薬品工業株式会社 Bacillus amyloliquefaciens strain and antibacterial composition containing the strain
US11331351B2 (en) 2015-01-23 2022-05-17 Novozymes A/S Bacillus strains improving health and performance of production animals
DK3261653T3 (en) * 2015-01-23 2019-12-16 Novozymes As Bacillus subtilis subspecies
CN107567493B (en) 2015-01-23 2021-11-16 诺维信公司 Bacillus strains for improving the health and performance of production animals
US10201574B1 (en) 2015-09-16 2019-02-12 Church & Dwight Co., Inc. Methods of microbial treatment of poultry
CA3016203A1 (en) 2016-02-29 2017-09-08 Microbial Discovery Group, Llc Direct-fed microbials
US10617134B2 (en) 2016-04-15 2020-04-14 Ascus Biosciences, Inc. Methods for improving agricultural production of fowl by administration of microbial compositions or purified strains thereof
US11298383B2 (en) 2016-05-20 2022-04-12 Church & Dwight Co., Inc. Lactobacillus and bacillus based direct fed microbial treatment for poultry and method of use
WO2017205645A1 (en) 2016-05-25 2017-11-30 Church & Dwight Co., Inc. Bacillus compositions and methods of use with ruminants
US11173184B2 (en) 2016-05-31 2021-11-16 Evonik Operations Gmbh Bacillus subtilis strain with probiotic activity
CN106957805B (en) * 2017-01-21 2020-10-23 南京钱塘洪泰生物科技有限公司 Bacillus GBacilus-9 strain with bacteriostatic effect and separation method and application thereof
WO2018165252A1 (en) * 2017-03-07 2018-09-13 Bioresource International, Inc. Feed additive formulation and methods of making and using the same
PE20200178A1 (en) 2017-03-14 2020-01-24 Chr Hansen As BACILLUS SUBTILIS STRAINS THAT IMPROVE PERFORMANCE PARAMETERS IN ANIMALS
CN107058182B (en) * 2017-04-19 2018-10-23 刘冰冰 A kind of bacillus amyloliquefaciens and Death Valley bacillus compounding microbial bacterial agent and its preparation method and application
JP7104078B2 (en) * 2017-06-30 2022-07-20 エボニック オペレーションズ ゲーエムベーハー Bacterial strain with probiotic activity
US11622569B2 (en) 2017-07-24 2023-04-11 Church & Dwight Co., Inc. Bacillus microbial terroir for pathogen control in swine
EP3447122A1 (en) * 2017-08-24 2019-02-27 Evonik Degussa GmbH Bacillus subtilis strain with probiotic activity
WO2019038153A1 (en) * 2017-08-24 2019-02-28 Evonik Degussa Gmbh Bacillus subtilis strain with probiotic activity
US11825862B2 (en) 2017-10-18 2023-11-28 Native Microbials, Inc. Fowl production by administration of a synthetic bioensemble of microbes or purified strains thereof
CN108208316B (en) * 2018-01-24 2021-02-02 吉林省农业科学院 Siamese bacillus-containing feed
CN108004145B (en) * 2018-01-24 2021-03-02 吉林省农业科学院 Black fungus wall breaking method
WO2019175782A1 (en) 2018-03-12 2019-09-19 Better Air International Limited Compositions comprising bacterial strains and use thereof in controlling pathogenic microorganisms
WO2019175783A1 (en) * 2018-03-12 2019-09-19 Better Air International Limited Compositions comprising bacterial strains and use thereof in controlling pathogenic microorganisms
WO2019175777A1 (en) 2018-03-12 2019-09-19 Better Air International Limited Compositions comprising bacterial strains and use thereof in controlling pathogenic microorganisms
WO2019175780A1 (en) 2018-03-12 2019-09-19 Better Air International Limited Compositions comprising bacterial strains and use thereof in controlling pathogenic microorganisms
CN112805367A (en) * 2018-06-07 2021-05-14 阿尔图根治疗有限公司 Methods and compositions for treating clostridium difficile
KR102178350B1 (en) * 2018-07-11 2020-11-11 대한민국 Bacillus safensis strain with antibiotic activity and antibiotic use thereof
MX2021003598A (en) 2018-09-28 2021-05-28 Microbial Discovery Group Llc Microorganisms for plant pathogen inhibition.
KR102173953B1 (en) 2018-10-19 2020-11-04 중앙대학교 산학협력단 Novel Bacillus velezensis KD1 Strain having High Proteolysis Ability and Antimicrobial Activity
CN109619283B (en) * 2019-01-04 2022-10-04 大连民族大学 Method for improving fermentation efficiency of soybean meal
CN109730198B (en) * 2019-01-04 2022-10-04 大连民族大学 Method for improving soybean meal fermentation efficiency by using response surface experiment
WO2020165057A1 (en) * 2019-02-11 2020-08-20 Evonik Operations Gmbh Compositions containing bacillaene producing bacteria or preparations thereof
EP3941213A4 (en) * 2019-03-19 2022-12-21 Microbial Discovery Group, LLC Microbial strains for virus inhibition
US20220233612A1 (en) * 2019-05-31 2022-07-28 South Dakota Board Of Regents Technology Transfer Office Probiotics to inhibit enteric pathogens
CN110368394B (en) * 2019-06-25 2022-10-11 华中农业大学 Application of avilamycin in inhibition drug of clostridium perfringens of pigs
CN114929027A (en) * 2019-08-22 2022-08-19 微生物发现集团有限责任公司 Inhibition method using microbial strains and antibiotics
CN110791450B (en) * 2019-11-22 2021-01-19 北京理工大学 Strain Am101 capable of degrading multiple beta-lactam antibiotics and application thereof
CN111690578B (en) * 2020-07-31 2021-11-23 山东佐田氏生物科技有限公司 Salt and alkali resistant Siamese bacillus and production method and application of viable bacteria preparation thereof
MX2023002027A (en) * 2020-08-21 2023-03-15 Microbial Discovery Group Llc Microbial strains and antibiotics.
CN112760251A (en) * 2021-01-05 2021-05-07 安徽农业大学 Compound bacillus probiotics and preparation and application thereof
CN113151069B (en) * 2021-04-01 2022-07-26 安杰利(重庆)生物科技有限公司 Bacillus subtilis and application thereof in preparation of antibacterial peptide and feed
CN113308397B (en) * 2021-05-19 2022-05-13 浙江大学 Probiotics for inhibiting clostridium perfringens and screening method and application thereof
CN113234631A (en) * 2021-05-20 2021-08-10 广东海纳川生物科技股份有限公司 Bacillus licheniformis and fermentation method and application thereof
CN114836335B (en) * 2021-11-11 2023-09-05 施可丰化工股份有限公司 Bacillus saxifragilis T1-5 and application thereof
CN115449491A (en) * 2021-12-28 2022-12-09 唐人神集团股份有限公司 Bacillus licheniformis with efficient antibacterial function and application thereof
CN115428925B (en) * 2022-11-08 2023-03-24 四川大学 Preparation method of dried turnips

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100287825B1 (en) * 1999-05-15 2001-04-16 이태일 Probiotics For Feed Additives
CN101076585A (en) 2003-08-14 2007-11-21 生物平衡公司 Bacterial strains, compositions including same and probiotic use thereof
US7754469B2 (en) 2005-11-30 2010-07-13 Agtech Products, Inc Microorganisms and methods for treating poultry
US8021654B2 (en) 2008-03-14 2011-09-20 Danisco A/S Methods of treating pigs with Bacillus strains
MX2011002889A (en) * 2008-09-17 2011-09-26 Agraquest Inc Method for using a bacillus subtilis strain to enhance animal health.
US8802079B2 (en) * 2008-12-19 2014-08-12 Chr. Hansen A/S Bile resistant Bacillus composition
KR101370942B1 (en) * 2012-04-05 2014-03-12 씨제이제일제당 (주) Novel Bacillus subtilis
KR101370941B1 (en) * 2012-04-05 2014-03-12 씨제이제일제당 (주) Novel Bacillus subtilis
KR101658046B1 (en) * 2013-01-14 2016-09-20 한국생명공학연구원 Bacillus sp. KR-OF1 as a novel strain with antibacterial activity and use thereof
KR101618220B1 (en) * 2014-02-21 2016-05-18 대한민국 A novel Bacillus sp. strain and use thereof

Also Published As

Publication number Publication date
BR112014025119B1 (en) 2022-04-19
DK2836589T3 (en) 2018-10-29
AU2013246850A1 (en) 2014-10-02
CN104487566B (en) 2018-04-10
HK1201558A1 (en) 2015-09-04
BR112014025119A2 (en) 2021-06-01
EA028359B1 (en) 2017-11-30
JP6212108B2 (en) 2017-10-11
CN104487566A (en) 2015-04-01
MX2014012098A (en) 2014-11-21
TR201815560T4 (en) 2018-11-21
EP3486313A1 (en) 2019-05-22
US20150079058A1 (en) 2015-03-19
ES2695149T3 (en) 2019-01-02
EP2836589A1 (en) 2015-02-18
US9844573B2 (en) 2017-12-19
US20180200309A1 (en) 2018-07-19
MX357230B (en) 2018-07-02
CA2869036C (en) 2021-06-08
EA201491838A1 (en) 2015-01-30
JP2015517809A (en) 2015-06-25
AU2013246850B2 (en) 2018-03-29
WO2013153159A1 (en) 2013-10-17
PH12014502283B1 (en) 2014-12-15
KR102128560B1 (en) 2020-07-01
US10702560B2 (en) 2020-07-07
EP2836589B1 (en) 2018-08-15
CA2869036A1 (en) 2013-10-17
PL2836589T3 (en) 2019-02-28
KR20140148488A (en) 2014-12-31

Similar Documents

Publication Publication Date Title
PH12014502283A1 (en) Antibiotic sensitive bacillus strains having antimicrobial effect against e. coli and clostridium perfringens and having high sporulation capacity
PH12019502073A1 (en) Bacillus subtilis strains improving animal performance parameters
JP2015517809A5 (en)
CY1119911T1 (en) BACTERIUM EXECUTIVE ISOLATED BY SWINE
PH12014502243A1 (en) Novel bacillus subtilis
MX2021000804A (en) Antifungal paenibacillus strains, fusaricidin-type compounds, and their use.
TR201911377T4 (en) Compositions containing bacterial strains.
ZA201701334B (en) Compositions containing lipo-chitooligosaccharide and microorganism for enhancing plant growth
MX338032B (en) Nematocidal composition comprising bacillus subtilis and bacillus licheniformis.
MX2020001666A (en) Biopesticides.
PH12017500679A1 (en) Insecticidal polypeptides having improved activity spectrum and uses thereof
WO2010151784A3 (en) Antimicrobial compounds
UA99450C2 (en) Bacillus smithii strain tbmi12 mscl p737 (endospores, mutants, breeds, derivates) for the protection against action of enteropathogenic bacteria
MX2017012073A (en) Minocycline compounds for biodefense.
PH12018500069A1 (en) Novel lactobacillus sp. microorganisms, and composition for animal feed comprising same
MY192552A (en) A fertilizer composition
MY193328A (en) Lactobacillus salivarius cjls1511, animal feed additive composition comprising same bacterium or dead cells thereof, and method for producing same dead cells
WO2019027224A3 (en) Peptide targeting mycobacterium tuberculosis toxin-antitoxin system and use thereof
MX2014016016A (en) Production and application of protozoa cultures of histomonas meleagridis (h. meleagridis).
MX348626B (en) Bionematicide composition and method for controlling phytopathogenic nematodes using the same.
MX2015017262A (en) Highly siderophore-producing bacterial mixture, production method thereof and use of same as a phytopathogen inhibitor.
MX2013011159A (en) Fluidizing mixture for a hydraulic composition.
PH12017501295A1 (en) Bacillus thuringiensis subsp. kurstaki and bacillus thuringiensis subsp. aizawai combination formulations
TH148820B (en) Bacillus strains that are sensitive to antibiotics that have inhibitory effects on the growth of microorganisms. E. coli and Clostridium Perfect ring and high spore formation ability.
EA201991944A1 (en) BACILLUS SUBTILIS STRAINS IMPROVING ANIMAL PRODUCTIVITY INDICATORS