PE28197A1 - NEW DERIVATIVES OF NONATETRAENOIC ACID - Google Patents
NEW DERIVATIVES OF NONATETRAENOIC ACIDInfo
- Publication number
- PE28197A1 PE28197A1 PE00012296A PE00012296A PE28197A1 PE 28197 A1 PE28197 A1 PE 28197A1 PE 00012296 A PE00012296 A PE 00012296A PE 00012296 A PE00012296 A PE 00012296A PE 28197 A1 PE28197 A1 PE 28197A1
- Authority
- PE
- Peru
- Prior art keywords
- compound
- refers
- formula
- new derivatives
- nonatetraenoic acid
- Prior art date
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I, EN DONDE: C7-C8 ES DOBLE ENLACE O TRIPLE ENLACE; R1 Y R2 SON INDEPENDIENTEMENTE ENTRE SI HALOGENO, ALQUILO INFERIOR O ALQUILENO DE 3 A 13 ATOMOS DE CARBONO; ESTE ULTIMO OPCIONALMENTE SUSTITUIDO CON UN ANILLO AROMATICO O HETEROAROMATICO DE 5-6 ATOMOS, Y UN SOLO HETEROATOMO OXIGENO, NITROGENO O AZUFRE. TAMBIEN SE REFIERE A UNA UNIDAD DE DOSIFICACION PARA LA ADMINISTRACION ORAL, QUE COMPRENDE: A)UN COMPUESTO RETINOIDE CON ACTIVIDAD RARO (RECEPTOR NUCLEAR DEL ACIDO RETINOICO); B)UN COMPUESTO DE FORMULA I, SU SAL, ESTER O AMIDA FARMACEUTICAMENTE ACEPTABLE; DONDE (A) ES UNO O DIEZ VECES LA DOSIS DE (B). SE USA EN EL TRATAMIENTO DE TUMORES SOLIDOS, LEUCEMIA O ACNEIT REFERS TO A COMPOUND OF FORMULA I, WHERE: C7-C8 IS DOUBLE LINK OR TRIPLE LINK; R1 AND R2 ARE INDEPENDENTLY BETWEEN HALOGEN, LOWER RENT OR ALKYLENE FROM 3 TO 13 CARBON ATOMS; THIS LAST OPTIONALLY REPLACED WITH A 5-6 ATOM AROMATIC OR HETEROAROMATIC RING, AND A SINGLE OXYGEN, NITROGEN OR SULFUR HETEROATOM. IT ALSO REFERS TO A DOSAGE UNIT FOR ORAL ADMINISTRATION, WHICH INCLUDES: A) A RETINOID COMPOUND WITH RARE ACTIVITY (NUCLEAR RECEPTOR OF RETINOIC ACID); B) A COMPOUND OF FORMULA I, ITS SALT, ESTER OR AMIDA PHARMACEUTICALLY ACCEPTABLE; WHERE (A) IS ONE OR TEN TIMES THE DOSE OF (B). IT IS USED IN THE TREATMENT OF SOLID TUMORS, LEUKEMIA OR ACNE
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39398095A | 1995-02-24 | 1995-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE28197A1 true PE28197A1 (en) | 1997-08-20 |
Family
ID=23557042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE00012296A PE28197A1 (en) | 1995-02-24 | 1996-02-21 | NEW DERIVATIVES OF NONATETRAENOIC ACID |
Country Status (8)
| Country | Link |
|---|---|
| AR (1) | AR002033A1 (en) |
| BR (1) | BR9600805A (en) |
| CO (1) | CO4700434A1 (en) |
| PE (1) | PE28197A1 (en) |
| PL (1) | PL184625B1 (en) |
| TR (1) | TR199600141A2 (en) |
| UY (1) | UY24174A1 (en) |
| ZA (1) | ZA961250B (en) |
-
1996
- 1996-02-16 ZA ZA961250A patent/ZA961250B/en unknown
- 1996-02-19 TR TR96/00141A patent/TR199600141A2/en unknown
- 1996-02-21 PE PE00012296A patent/PE28197A1/en not_active Application Discontinuation
- 1996-02-22 CO CO96008294A patent/CO4700434A1/en unknown
- 1996-02-23 AR ARP960101489A patent/AR002033A1/en active IP Right Grant
- 1996-02-23 PL PL96312913A patent/PL184625B1/en not_active IP Right Cessation
- 1996-02-23 BR BR9600805A patent/BR9600805A/en not_active Application Discontinuation
- 1996-02-23 UY UY24174A patent/UY24174A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL184625B1 (en) | 2002-11-29 |
| UY24174A1 (en) | 2000-12-29 |
| TR199600141A2 (en) | 1996-10-21 |
| BR9600805A (en) | 1997-12-23 |
| ZA961250B (en) | 1996-08-26 |
| CO4700434A1 (en) | 1998-12-29 |
| AR002033A1 (en) | 1998-01-07 |
| PL312913A1 (en) | 1996-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |