PE20240635A1 - Nuevo co-reactivo de electroquimioluminiscencia y sistema de electroquimioluminiscencia que comprende el mismo - Google Patents

Nuevo co-reactivo de electroquimioluminiscencia y sistema de electroquimioluminiscencia que comprende el mismo

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Publication number
PE20240635A1
PE20240635A1 PE2023002432A PE2023002432A PE20240635A1 PE 20240635 A1 PE20240635 A1 PE 20240635A1 PE 2023002432 A PE2023002432 A PE 2023002432A PE 2023002432 A PE2023002432 A PE 2023002432A PE 20240635 A1 PE20240635 A1 PE 20240635A1
Authority
PE
Peru
Prior art keywords
electrochemiluminescence
reagent
same
electrochemioluminescence
new
Prior art date
Application number
PE2023002432A
Other languages
English (en)
Inventor
Ik-Soo Shin
Original Assignee
Elips Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020220016178A external-priority patent/KR102690985B1/ko
Application filed by Elips Diagnostics Inc filed Critical Elips Diagnostics Inc
Publication of PE20240635A1 publication Critical patent/PE20240635A1/es

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    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • C09K11/07Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials having chemically interreactive components, e.g. reactive chemiluminescent compositions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/73Unsubstituted amino or imino radicals
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10Non-macromolecular compounds
    • C09K2211/1018Heterocyclic compounds
    • C09K2211/1025Heterocyclic compounds characterised by ligands
    • C09K2211/1029Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/66Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light electrically excited, e.g. electroluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Control Of Indicators Other Than Cathode Ray Tubes (AREA)
  • Pyridine Compounds (AREA)

Abstract

La presente invencion se refiere a un nuevo co-reactivo de electroquimioluminiscencia (ECL) y a un sistema de electroquimioluminiscencia que incluye el mismo. El co-reactivo de electroquimioluminiscencia caracterizado porque comprende un compuesto representado por la Formula Quimica ?, o una sal farmaceuticamente aceptable del mismo: en la que cada R1 y R2 pueden ser iguales o diferentes entre si, y representar uno seleccionado de: un atomo de H; un atomo de halogeno; un grupo alquilo de C1-C6 de cadena lineal, ramificada o ciclica; un grupo alcoxi C1-C6; y un grupo haloalquilo de C1-C6., se aplica a inmunoensayos y dispositivos de diagnostico basados en el mismo que utilizan un marcador electroquimioluminiscente de una especie luminiscente especifica (un compuesto de hidrocarburo aromatico policiclico), un compuesto complejo metalico, un punto cuantico o nanoparticulas, y similares, y tienen una senal de deteccion excelente y se pueden mejorar las condiciones de aplicacion de voltaje al medir.
PE2023002432A 2021-02-26 2022-02-23 Nuevo co-reactivo de electroquimioluminiscencia y sistema de electroquimioluminiscencia que comprende el mismo PE20240635A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20210026210 2021-02-26
KR1020220016178A KR102690985B1 (ko) 2021-02-26 2022-02-08 신규한 전기화학발광 공반응물 및 이를 포함하는 전기화학발광 시스템
PCT/KR2022/002654 WO2022182128A1 (ko) 2021-02-26 2022-02-23 신규한 전기화학발광 공반응물 및 이를 포함하는 전기화학발광 시스템

Publications (1)

Publication Number Publication Date
PE20240635A1 true PE20240635A1 (es) 2024-03-26

Family

ID=83049491

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2023002432A PE20240635A1 (es) 2021-02-26 2022-02-23 Nuevo co-reactivo de electroquimioluminiscencia y sistema de electroquimioluminiscencia que comprende el mismo

Country Status (12)

Country Link
US (1) US20230365859A1 (es)
EP (1) EP4299562A1 (es)
JP (1) JP2024515425A (es)
AU (1) AU2022226825A1 (es)
BR (1) BR112023017166A2 (es)
CA (1) CA3205524A1 (es)
CL (1) CL2023002503A1 (es)
CO (1) CO2023012669A2 (es)
IL (1) IL305429A (es)
MX (1) MX2023010037A (es)
PE (1) PE20240635A1 (es)
WO (1) WO2022182128A1 (es)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3081228C (en) * 2001-09-10 2022-02-15 Meso Scale Technologies, Llc Assay buffer, compositions containing the same, and methods of using the same
US7553448B2 (en) * 2002-06-20 2009-06-30 Bioveris Corporation Electrochemiluminescence flow cell and flow cell components
KR102176825B1 (ko) * 2018-01-04 2020-11-10 서울대학교 산학협력단 호모시스테인 검출용 전기화학발광 프로브
SG11202012634UA (en) * 2018-12-17 2021-01-28 Illumina Inc Flow cells and sequencing kits
CN114364815A (zh) * 2019-05-03 2022-04-15 中尺度技术有限责任公司 用于检测样本中的一个或多个目标分析物的试剂盒及其制备和使用方法

Also Published As

Publication number Publication date
JP2024515425A (ja) 2024-04-10
EP4299562A1 (en) 2024-01-03
MX2023010037A (es) 2023-11-22
AU2022226825A1 (en) 2023-09-14
BR112023017166A2 (pt) 2023-11-28
IL305429A (en) 2023-10-01
CL2023002503A1 (es) 2024-03-01
CO2023012669A2 (es) 2023-10-09
WO2022182128A1 (ko) 2022-09-01
CA3205524A1 (en) 2022-09-01
US20230365859A1 (en) 2023-11-16

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