PE20230174A1 - Composiciones para interrumpir la formacion de biopeliculas y para tratar trastornos relacionados con biopeliculas - Google Patents
Composiciones para interrumpir la formacion de biopeliculas y para tratar trastornos relacionados con biopeliculasInfo
- Publication number
- PE20230174A1 PE20230174A1 PE2022001941A PE2022001941A PE20230174A1 PE 20230174 A1 PE20230174 A1 PE 20230174A1 PE 2022001941 A PE2022001941 A PE 2022001941A PE 2022001941 A PE2022001941 A PE 2022001941A PE 20230174 A1 PE20230174 A1 PE 20230174A1
- Authority
- PE
- Peru
- Prior art keywords
- biofilm
- linear
- disorders related
- disrupting
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- XPRZAEWSYWTDSQ-UHFFFAOYSA-N S-propyl propanethiosulfinate Chemical compound CCCSS(=O)CCC XPRZAEWSYWTDSQ-UHFFFAOYSA-N 0.000 abstract 4
- OUIASSQOLAEHIR-UHFFFAOYSA-N Propyl propane thiosulfonate Chemical compound CCCSS(=O)(=O)CCC OUIASSQOLAEHIR-UHFFFAOYSA-N 0.000 abstract 2
- 208000006413 Digital Dermatitis Diseases 0.000 abstract 1
- 206010048038 Wound infection Diseases 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- JDLKFOPOAOFWQN-UHFFFAOYSA-N allicin Chemical compound C=CCSS(=O)CC=C JDLKFOPOAOFWQN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 208000023867 digital dermatitis in cattle Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 208000004396 mastitis Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
- A01N41/04—Sulfonic acids; Derivatives thereof
- A01N41/08—Sulfonic acid halides; alpha-Hydroxy-sulfonic acids; Amino-sulfonic acids; Thiosulfonic acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P1/00—Disinfectants; Antimicrobial compounds or mixtures thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/10—Feeding-stuffs specially adapted for particular animals for ruminants
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/04—Thiosulfonates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Emergency Medicine (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Food Science & Technology (AREA)
- Pest Control & Pesticides (AREA)
- Animal Husbandry (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Birds (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
La presente invencion se refiere a compuestos derivados de tiosulfonato de propilpropano (PTSO) y tiosulfinato de propilpropano (PTS) de Formula I; en donde R1 y R2 se seleccionan independientemente de alquilo lineal o ramificado, alquenilo lineal o ramificado, alquinilo lineal o ramificado opcionalmente sustituido, arilo, cicloalquilo, entre otros, cada uno opcionalmente sustituido y n es 1, 2 o 3. Tambien proporciona una composicion que los comprende, la cual esta sustancialmente libre de tiosulfinato de dialilo; siendo utiles para tratar infecciones y reducir o degradar biopeliculas, tanto in vivo como in vitro, preferentemente formadas a partir de P. aeruginosa y S. aureus. En particular, en el tratamiento de trastornos relacionados con biopeliculas, incluyendo, pero sin limitarse a, mastitis, dermatitis digital e infecciones cronicas de heridas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20163157 | 2020-03-13 | ||
| PCT/NL2021/050168 WO2021182958A1 (en) | 2020-03-13 | 2021-03-12 | Compositions for disrupting biofilm formation and for treating biofilm-related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20230174A1 true PE20230174A1 (es) | 2023-02-01 |
Family
ID=69844589
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2022001941A PE20230174A1 (es) | 2020-03-13 | 2021-03-12 | Composiciones para interrumpir la formacion de biopeliculas y para tratar trastornos relacionados con biopeliculas |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20230000811A1 (es) |
| EP (1) | EP4117654A1 (es) |
| JP (1) | JP2023518928A (es) |
| KR (1) | KR20220154142A (es) |
| CN (1) | CN115397409A (es) |
| AU (1) | AU2021234626A1 (es) |
| BR (1) | BR112022017193A2 (es) |
| CA (1) | CA3168188A1 (es) |
| CL (1) | CL2022002463A1 (es) |
| CO (1) | CO2022013742A2 (es) |
| EC (1) | ECSP22079392A (es) |
| IL (1) | IL296302A (es) |
| MX (1) | MX2022011359A (es) |
| PE (1) | PE20230174A1 (es) |
| WO (1) | WO2021182958A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2023200340A1 (en) | 2022-04-14 | 2023-10-19 | AHV International B.V. | Compounds for reducing lactation and improving health |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2311373B1 (es) | 2006-09-27 | 2009-12-21 | Dmc Research Center, S.L. | "utilizacion de un compuesto antibacteriano derivado de alliaceas, como aditivos en alimentacion animal". |
| FR2958118B1 (fr) * | 2010-04-01 | 2012-06-15 | Pancosma Sa Pour L Ind Des Produits Biochimiques | Utilisation d'au moins un thiosulfinate ou thiosulfonate de dialkyle pour reduire le nombre d'apicomplexes chez un animal monogastrique |
| JP6088433B2 (ja) * | 2010-12-08 | 2017-03-01 | ダンマークス テクニスク ユニバーシテット | アホエン誘導体を製造するためのプロセス |
| US10086018B2 (en) * | 2011-02-04 | 2018-10-02 | Joseph E. Kovarik | Method and system for reducing the likelihood of colorectal cancer in a human being |
| EP3338774A1 (fr) * | 2016-12-23 | 2018-06-27 | Mixscience | Composition à base de composés thiosulfinate et/ou de thiosulfonate pour son utilisation dans la prévention des infections bactériennes chez les animaux aquatiques |
-
2021
- 2021-03-12 EP EP21712254.8A patent/EP4117654A1/en active Pending
- 2021-03-12 MX MX2022011359A patent/MX2022011359A/es unknown
- 2021-03-12 PE PE2022001941A patent/PE20230174A1/es unknown
- 2021-03-12 JP JP2022554867A patent/JP2023518928A/ja active Pending
- 2021-03-12 IL IL296302A patent/IL296302A/en unknown
- 2021-03-12 WO PCT/NL2021/050168 patent/WO2021182958A1/en unknown
- 2021-03-12 KR KR1020227034718A patent/KR20220154142A/ko unknown
- 2021-03-12 CA CA3168188A patent/CA3168188A1/en active Pending
- 2021-03-12 US US17/905,772 patent/US20230000811A1/en active Pending
- 2021-03-12 BR BR112022017193A patent/BR112022017193A2/pt unknown
- 2021-03-12 CN CN202180020565.4A patent/CN115397409A/zh active Pending
- 2021-03-12 AU AU2021234626A patent/AU2021234626A1/en active Pending
-
2022
- 2022-09-09 CL CL2022002463A patent/CL2022002463A1/es unknown
- 2022-09-26 CO CONC2022/0013742A patent/CO2022013742A2/es unknown
- 2022-10-12 EC ECSENADI202279392A patent/ECSP22079392A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021182958A1 (en) | 2021-09-16 |
| US20230000811A1 (en) | 2023-01-05 |
| CL2022002463A1 (es) | 2023-06-16 |
| MX2022011359A (es) | 2022-12-02 |
| IL296302A (en) | 2022-11-01 |
| AU2021234626A1 (en) | 2022-09-29 |
| BR112022017193A2 (pt) | 2022-10-18 |
| ECSP22079392A (es) | 2022-11-30 |
| CN115397409A (zh) | 2022-11-25 |
| CO2022013742A2 (es) | 2022-10-31 |
| KR20220154142A (ko) | 2022-11-21 |
| JP2023518928A (ja) | 2023-05-09 |
| EP4117654A1 (en) | 2023-01-18 |
| CA3168188A1 (en) | 2021-09-16 |
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