PE20190654A1 - Plantas y metodos para aumentar y disminuir la sintesis de cannabinoides - Google Patents

Plantas y metodos para aumentar y disminuir la sintesis de cannabinoides

Info

Publication number
PE20190654A1
PE20190654A1 PE2019000396A PE2019000396A PE20190654A1 PE 20190654 A1 PE20190654 A1 PE 20190654A1 PE 2019000396 A PE2019000396 A PE 2019000396A PE 2019000396 A PE2019000396 A PE 2019000396A PE 20190654 A1 PE20190654 A1 PE 20190654A1
Authority
PE
Peru
Prior art keywords
cannabinoid
plants
decrease
methods
increase
Prior art date
Application number
PE2019000396A
Other languages
English (en)
Inventor
Robert F Roscow
Original Assignee
Canopy Growth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canopy Growth Corp filed Critical Canopy Growth Corp
Publication of PE20190654A1 publication Critical patent/PE20190654A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Referido a una planta del genero cannabis, caracterizada porque comprende un contenido total de cannabinoides; un primer cannabinoide que comprende mas del 10% del contenido total de cannabinoides en peso seco; un segundo cannabinoide que comprende menos del 10% del contenido total de cannabinoide en peso seco; y material genetico modificado dentro de un genoma de la planta del genero cannabis. Tambien se refiere a un metodo para controlar la sintesis de cannabinoides. Este metodo comprende la manipulacion de la ruta biosintetica de los cannabinoides para producir plantas del genero cannabis con proporciones y concentraciones de cannabinoides no naturales.
PE2019000396A 2016-08-18 2017-08-18 Plantas y metodos para aumentar y disminuir la sintesis de cannabinoides PE20190654A1 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201662376521P 2016-08-18 2016-08-18
US201662385102P 2016-09-08 2016-09-08
US201662416084P 2016-11-01 2016-11-01
US201662416098P 2016-11-01 2016-11-01
US201662429049P 2016-12-01 2016-12-01
US201662429039P 2016-12-01 2016-12-01
US201662429046P 2016-12-01 2016-12-01

Publications (1)

Publication Number Publication Date
PE20190654A1 true PE20190654A1 (es) 2019-05-08

Family

ID=61197425

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2019000396A PE20190654A1 (es) 2016-08-18 2017-08-18 Plantas y metodos para aumentar y disminuir la sintesis de cannabinoides

Country Status (12)

Country Link
US (1) US11466283B2 (es)
EP (1) EP3500090A4 (es)
CN (1) CN109890202A (es)
AU (1) AU2017313843A1 (es)
BR (1) BR112019003024A8 (es)
CA (1) CA3033875A1 (es)
CL (1) CL2019000434A1 (es)
CO (1) CO2019002123A2 (es)
MX (1) MX2019001968A (es)
PE (1) PE20190654A1 (es)
WO (1) WO2018035450A1 (es)
ZA (1) ZA201900986B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
WO2019152736A1 (en) 2018-01-31 2019-08-08 Canopy Holdings, LLC Hemp powder
EP3755318B1 (en) * 2018-02-20 2022-08-24 MyMD Pharmaceuticals, Inc. Genetically modified cannabis sativa plants and modified cannabinoid compounds for treatment of substance addiction and other disorders
CA3105433C (en) * 2018-08-17 2023-07-11 Canbreed Ltd. Cannabis plant cells with reduced delta-9-tetrahydrocannabinol (thc) content
US11040932B2 (en) 2018-10-10 2021-06-22 Treehouse Biotech, Inc. Synthesis of cannabigerol
US20220002764A1 (en) * 2018-11-14 2022-01-06 Manus Bio Inc. Microbial cells and methods for producing cannabinoids
CA3130763A1 (en) 2019-02-25 2020-09-03 Ginkgo Bioworks, Inc. Biosynthesis of cannabinoids and cannabinoid precursors
WO2020227611A1 (en) * 2019-05-09 2020-11-12 New West Genetics Inc. Methods for production of low cost terpenoids, including cannabinoids, and varieties adapted for large-scale planting and density optimization including cannabinoid preservation
CN115942868A (zh) * 2019-05-29 2023-04-07 优良种子有限责任公司 产量提高的大麻植物
EP3999490A4 (en) * 2019-07-12 2023-03-08 Canopy Growth Corporation CANNABINOID DERIVATIVES
CN112441952B (zh) * 2019-08-28 2021-08-06 析木津生物医药(广州)有限公司 一种大麻二酚-3-磺酸及其制备方法和应用、大麻二酚衍生物
US20220356484A1 (en) * 2019-09-06 2022-11-10 Dr. James Berman Genetic modification of plants
AU2020357893A1 (en) * 2019-10-01 2022-04-14 Empyrean Neuroscience, Inc. Genetically modified plants and methods of making the same
CA3152875A1 (en) * 2019-10-01 2021-04-08 Thomas Henley Genetically modified plants and methods of making the same
WO2021062559A1 (en) * 2019-10-02 2021-04-08 Canopy Growth Corporation Cannabinoid derivatives
JP2022552952A (ja) * 2019-10-11 2022-12-21 ナショナル ユニヴァーシティ オブ シンガポール 新規芳香族プレニルトランスフェラーゼを使用したカンナビノイド前駆体の生合成
EP4055172A1 (en) * 2019-11-04 2022-09-14 Agriculture Victoria Services Pty Ltd A method to produce targeted gene editing constructs
EP4156912A4 (en) * 2020-05-27 2024-01-03 Canbreed Ltd CANNABIS PLANTS WITH IMPROVED AGRONOMIC CHARACTERISTICS
CN116322314A (zh) * 2020-07-13 2023-06-23 优良种子有限责任公司 具有改变的大麻素含量的大麻
WO2022015976A2 (en) * 2020-07-16 2022-01-20 Canopy Growth Corporation Cannabis plant with increased cannabigerolic acid
WO2022081681A1 (en) * 2020-10-13 2022-04-21 Canopy Growth Corporation Cannabis plant with increased cannabichromenic acid
KR20230143960A (ko) * 2022-04-05 2023-10-13 주식회사 진코어 유전자 교정 단백질을 포함하는 대마 유전자 교정용 조성물 및 이를 이용한 대마 유전자 교정 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2770774C (en) 2009-08-12 2020-07-14 National Research Council Of Canada Aromatic prenyltransferase from cannabis
US9611460B2 (en) 2010-04-15 2017-04-04 National Research Council Of Canada Genes and proteins for aromatic polyketide synthesis
US20160177404A1 (en) 2011-08-18 2016-06-23 Courtagen Life Sciences Inc. Cannabis genomes and uses thereof
US20140245494A1 (en) * 2013-02-25 2014-08-28 Ytzchak Cohen Cannabis plant named erez
US10441617B2 (en) 2013-03-15 2019-10-15 Biotech Institute, Llc Breeding, production, processing and use of medical cannabis
ES2730378T3 (es) 2014-08-27 2019-11-11 Caribou Biosciences Inc Procedimientos para incrementar la eficiencia de la modificación mediada por Cas9
MX2017015304A (es) * 2015-05-28 2018-07-06 Tweed Inc Plantas de cannabis que tienen expresion modificada de acido tetrahidrocannabinolico sintasa.

Also Published As

Publication number Publication date
EP3500090A4 (en) 2020-01-08
US11466283B2 (en) 2022-10-11
CA3033875A1 (en) 2018-02-22
CN109890202A (zh) 2019-06-14
ZA201900986B (en) 2019-12-18
EP3500090A1 (en) 2019-06-26
BR112019003024A8 (pt) 2019-09-10
WO2018035450A1 (en) 2018-02-22
AU2017313843A1 (en) 2019-03-07
US20200181631A1 (en) 2020-06-11
MX2019001968A (es) 2019-10-02
CL2019000434A1 (es) 2019-05-24
BR112019003024A2 (pt) 2019-05-14
CO2019002123A2 (es) 2019-05-31

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