PE20110069A1 - Compuestos de tetraciclina sustituidos - Google Patents

Compuestos de tetraciclina sustituidos

Info

Publication number
PE20110069A1
PE20110069A1 PE2010000229A PE2010000229A PE20110069A1 PE 20110069 A1 PE20110069 A1 PE 20110069A1 PE 2010000229 A PE2010000229 A PE 2010000229A PE 2010000229 A PE2010000229 A PE 2010000229A PE 20110069 A1 PE20110069 A1 PE 20110069A1
Authority
PE
Peru
Prior art keywords
alkenyl
alkyl
tetracycline compounds
substituted tetracycline
dimethylamine
Prior art date
Application number
PE2010000229A
Other languages
English (en)
Spanish (es)
Inventor
Joel Berniac
Todd Bowser
Original Assignee
Paratek Pharm Innc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Paratek Pharm Innc filed Critical Paratek Pharm Innc
Publication of PE20110069A1 publication Critical patent/PE20110069A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
PE2010000229A 2008-04-14 2010-04-14 Compuestos de tetraciclina sustituidos PE20110069A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4477308P 2008-04-14 2008-04-14
US12/423,718 US20100022483A1 (en) 2008-04-14 2009-04-14 Substituted Tetracycline Compounds
PCT/US2009/002344 WO2009128913A1 (en) 2008-04-14 2009-04-14 Substituted tetracycline compounds

Publications (1)

Publication Number Publication Date
PE20110069A1 true PE20110069A1 (es) 2011-01-31

Family

ID=41199392

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2010000229A PE20110069A1 (es) 2008-04-14 2010-04-14 Compuestos de tetraciclina sustituidos

Country Status (7)

Country Link
US (1) US20100022483A1 (enExample)
EP (1) EP2276342A4 (enExample)
JP (1) JP2011517697A (enExample)
AU (1) AU2009236631A1 (enExample)
CA (1) CA2721399A1 (enExample)
PE (1) PE20110069A1 (enExample)
WO (1) WO2009128913A1 (enExample)

Families Citing this family (11)

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US7485319B2 (en) 2003-07-25 2009-02-03 Warner Chilcott Company, Inc. Doxycycline metal complex in a solid dosage form
MX2007008724A (es) * 2005-01-21 2007-09-21 Warner Chilcott Co Inc Complejo metalico de tetraciclina en una forma de dosificacion solida.
BRPI0908951A2 (pt) 2008-03-05 2017-01-17 Paratek Pharm Innc compostos de minociclina e método de uso dos mesmos
PL3000805T3 (pl) 2008-08-08 2018-04-30 Tetraphase Pharmaceuticals, Inc. C7-fluoro podstawione związki tetracyklinowe
PL2427425T3 (pl) 2009-05-08 2017-08-31 Tetraphase Pharmaceuticals, Inc. Związki tetracyklinowe
HUE037852T2 (hu) 2009-08-28 2018-09-28 Tetraphase Pharmaceuticals Inc Tetraciklin-vegyületek
EP2854820A4 (en) * 2012-05-30 2015-11-25 Paratek Pharm Innc DERIVATIVES OF 7- (PHENYL DISUBSTITUTED) -TETTRACYCLINE
ES2712476T3 (es) 2012-08-31 2019-05-13 Tetraphase Pharmaceuticals Inc Compuestos de tetraciclina
WO2018075767A1 (en) 2016-10-19 2018-04-26 Tetraphase Pharmaceuticals, Inc. Crystalline forms of eravacycline
CA3042514A1 (en) 2016-11-01 2018-05-11 Paratek Pharmaceuticals, Inc. 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp)
WO2021183918A1 (en) * 2020-03-13 2021-09-16 Cmtx Biotech Inc. Methods of treating illnesses caused by coronavirus, swine flu and avian flu

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US2980584A (en) * 1957-10-29 1961-04-18 Pfizer & Co C Parenteral magnesium oxytetracycline acetic or lactic acid carboxamide vehicle preparation
US3062717A (en) * 1958-12-11 1962-11-06 Pfizer & Co C Intramuscular calcium tetracycline acetic or lactic acid carboxamide vehicle preparation
US3165531A (en) * 1962-03-08 1965-01-12 Pfizer & Co C 13-substituted-6-deoxytetracyclines and process utilizing the same
US3454697A (en) * 1965-06-08 1969-07-08 American Cyanamid Co Tetracycline antibiotic compositions for oral use
NL6607516A (enExample) * 1966-05-31 1967-12-01
DE1767891C3 (de) * 1968-06-28 1980-10-30 Pfizer Verfahren zur Herstellung von wäßrigen arzneilichen Lösungen für die parenterale, perorale und lokale Anwendung mit einem Gehalt an einem Tetracyclinderivat
US3957980A (en) * 1972-10-26 1976-05-18 Pfizer Inc. Doxycycline parenteral compositions
DE2442829A1 (de) * 1974-09-06 1976-03-18 Merck Patent Gmbh Tetracyclische verbindungen und verfahren zu ihrer herstellung
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
US4126680A (en) * 1977-04-27 1978-11-21 Pfizer Inc. Tetracycline antibiotic compositions
US4806529A (en) * 1982-11-18 1989-02-21 Trustees Of Tufts College, Tufts University Tetracycline activity enhancement
US5064821A (en) * 1982-11-18 1991-11-12 Trustees Of Tufts College Method and compositions for overcoming tetracycline resistance within living cells
US5589470A (en) * 1990-02-26 1996-12-31 Trustees Of Tufts College Reducing tetracycline resistance in living cells
US4806372A (en) * 1985-02-15 1989-02-21 Georgia Oil & Gas Co., Inc. Nitrite-free-curing of bacon and product thereof
US6756365B2 (en) * 1991-11-06 2004-06-29 Trustees Of Tufts College Reducing tetracycline resistance in living cells
WO1999037307A1 (en) * 1998-01-23 1999-07-29 Trustees Of Tufts College Pharmaceutically active compounds and methods of use thereof
US6256365B1 (en) * 1999-08-16 2001-07-03 Analogic Corporation Apparatus and method for reconstruction of images in a computed tomography system using oblique slices
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US6849615B2 (en) * 1999-09-14 2005-02-01 Paratek Pharmaceuticals, Inc. 13-substituted methacycline compounds
CA2672722C (en) * 1999-09-14 2013-11-05 Trustees Of Tufts College Methods of preparing substituted tetracyclines with transition metal-based chemistries
US6833365B2 (en) * 2000-01-24 2004-12-21 Trustees Of Tufts College Tetracycline compounds for treatment of Cryptosporidium parvum related disorders
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CA2409063A1 (en) * 2000-05-15 2001-11-22 Mark L. Nelson 7-substituted fused ring tetracycline compounds
US20020132798A1 (en) * 2000-06-16 2002-09-19 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
US20040224927A1 (en) * 2000-06-16 2004-11-11 Trustees Of Tufts College 7-N-substituted phenyl tetracycline compounds
US20020128238A1 (en) * 2000-06-16 2002-09-12 Nelson Mark L. 7-phenyl-substituted tetracycline compounds
DE60122341T2 (de) * 2000-07-07 2007-08-09 The Trustees Of Tufts College, Medford 9-substituierte minocyclin verbindungen
US6624168B2 (en) * 2000-07-07 2003-09-23 Trustees Of Tufts College 7,8 and 9-substituted tetracycline compounds
US7094806B2 (en) * 2000-07-07 2006-08-22 Trustees Of Tufts College 7, 8 and 9-substituted tetracycline compounds
MXPA03000056A (es) * 2000-07-07 2003-07-14 Tufts College Compuestos de tetraciclina sustituidos en posicion 7.
US20050143353A1 (en) * 2000-07-07 2005-06-30 Paratek Pharmaceuticals, Inc. 13-Substituted methacycline compounds
US7553828B2 (en) * 2001-03-13 2009-06-30 Paratek Pharmaceuticals, Inc. 9-aminomethyl substituted minocycline compounds
WO2002072506A2 (en) * 2001-03-13 2002-09-19 Paratek Pharmaceuticals, Inc. 7-pyrollyl tetracycline compounds and methods of use thereof
EP1241160A1 (en) * 2001-03-13 2002-09-18 Glaxo Group Limited Tetracycline derivatives and their use as antibiotic agents
ATE404528T1 (de) * 2001-03-13 2008-08-15 Paratek Pharm Innc 7,9 substituierte tetracyclinverbindungen
JP2004530661A (ja) * 2001-03-14 2004-10-07 パラテック ファーマシューティカルズ インコーポレイテッド 抗真菌剤としての置換テトラサイクリン化合物
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US8088820B2 (en) * 2001-04-24 2012-01-03 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for the treatment of malaria
US20060194773A1 (en) * 2001-07-13 2006-08-31 Paratek Pharmaceuticals, Inc. Tetracyline compounds having target therapeutic activities
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JP2009502809A (ja) * 2005-07-21 2009-01-29 パラテック ファーマシューティカルズ インコーポレイテッド １０−置換テトラサイクリンおよびその使用方法
EP1991236A2 (en) * 2006-01-24 2008-11-19 Paratek Pharmaceuticals, Inc. Methods of increasing oral bioavailability of tetracyclines
US20080118979A1 (en) * 2006-05-15 2008-05-22 Paratek Pharmaceuticals, Inc. Methods of regulating expression of genes or of gene products using substituted tetracycline compounds
US8440646B1 (en) * 2006-10-11 2013-05-14 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of Bacillus anthracis infections
PT2120963T (pt) * 2006-12-21 2018-12-17 Paratek Pharm Innc Compostos tetraciclina substituídos para tratamento de distúrbios inflamatórios da pele
PT2109602E (pt) * 2006-12-21 2014-05-23 Paratek Pharm Innc Derivados de tetraciclina para o tratamento de infecções bacterianas, virais e parasitárias
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Also Published As

Publication number Publication date
CA2721399A1 (en) 2009-10-22
AU2009236631A1 (en) 2009-10-22
JP2011517697A (ja) 2011-06-16
EP2276342A4 (en) 2012-02-22
EP2276342A1 (en) 2011-01-26
US20100022483A1 (en) 2010-01-28
WO2009128913A1 (en) 2009-10-22

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