PE20091378A1 - Polipeptidos agonistas plexind1 - Google Patents

Polipeptidos agonistas plexind1

Info

Publication number
PE20091378A1
PE20091378A1 PE2009000023A PE2009000023A PE20091378A1 PE 20091378 A1 PE20091378 A1 PE 20091378A1 PE 2009000023 A PE2009000023 A PE 2009000023A PE 2009000023 A PE2009000023 A PE 2009000023A PE 20091378 A1 PE20091378 A1 PE 20091378A1
Authority
PE
Peru
Prior art keywords
plexind1
seq
agonist polypeptides
polypeptides
semaforin
Prior art date
Application number
PE2009000023A
Other languages
English (en)
Inventor
Ryan J Watts
Alexander W Koch
Vigne Marc Tessier-La
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of PE20091378A1 publication Critical patent/PE20091378A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

REFERIDA A UN POLIPEPTIDO QUE COMPRENDE UN FRAGMENTO DE SEMAFORINA SEMA3E QUIMERICO QUE CARECE DEL PRIMER SITIO DE ESCISION DE FURINA Y QUE COMPRENDE UN LIGANTE TAL COMO GRAG (SEC ID NO:2) Y GGGS (SEC ID NO:3). TAMBIEN ESTA REFERIDA A UN ACIDO NUCLEICO, UN VECTOR Y UNA CELULA HUESPED. DICHOS POLIPEPTIDOS SON AGONISTAS DE PLEXIND1 Y SON UTILES EN EL TRATAMIENTO DE ANGIOGENESIS ASOCIADA AL CANCER
PE2009000023A 2008-01-10 2009-01-09 Polipeptidos agonistas plexind1 PE20091378A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2029608P 2008-01-10 2008-01-10

Publications (1)

Publication Number Publication Date
PE20091378A1 true PE20091378A1 (es) 2009-10-14

Family

ID=40481787

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2009000023A PE20091378A1 (es) 2008-01-10 2009-01-09 Polipeptidos agonistas plexind1

Country Status (5)

Country Link
US (1) US20090181035A1 (es)
AR (1) AR070134A1 (es)
PE (1) PE20091378A1 (es)
TW (1) TW200934512A (es)
WO (1) WO2009089461A1 (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2781223B1 (en) 2007-10-19 2017-02-22 Rappaport Family Institute for Research in the Medical Sciences Compositions comprising semaphorins for use in the treatment of cancer
US9808506B2 (en) 2007-10-19 2017-11-07 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of cancer and methods of selection thereof
GB2493992A (en) 2011-08-26 2013-02-27 Fillaball Holdings Ltd Wheeled load-carrying apparatus
SG175417A1 (en) 2009-05-08 2011-12-29 Vaccinex Inc Anti-cd100 antibodies and methods for using the same
EP2385121A1 (en) * 2010-05-06 2011-11-09 Netris Pharma Antagonists of Sema3E/PlexinD1 interaction as anti-cancer agents
IT1400024B1 (it) * 2010-05-21 2013-05-17 Uni Politecnica Delle Marche Uso farmaceutico di semaforine.
JP6395606B2 (ja) 2011-10-11 2018-09-26 バクシネックス インコーポレーティッド 血液脳関門透過性の調節のためのセマフォリン−４ｄ結合分子の使用
US10494440B2 (en) 2012-05-11 2019-12-03 Vaccinex, Inc. Use of semaphorin-4D binding molecules to promote neurogenesis following stroke
WO2014181273A1 (en) * 2013-05-08 2014-11-13 University Of Manitoba Methods for treating inflammatory bowel disease
DK3013350T3 (da) 2013-06-25 2020-04-14 Vaccinex Inc Anvendelse af semaphorin-4D-hæmmende molekyler i kombination med en immunmodulerende terapi for at hæmme tumorvækst og metastaser
NZ630881A (en) 2013-10-10 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treatment of atherosclerosis
NZ630892A (en) 2013-10-21 2016-03-31 Vaccinex Inc Use of semaphorin-4d binding molecules for treating neurodegenerative disorders
JP6924708B2 (ja) * 2015-06-29 2021-08-25 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア Ｂ１ｓｐ融合タンパク質の治療薬、方法、および使用
KR102353086B1 (ko) * 2018-09-07 2022-01-20 아주대학교산학협력단 신규 면역독소 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003242512A1 (en) * 2002-07-11 2004-02-02 Sema Aps Use of compounds capable of inhibiting the proteolytic processing of semaphorins for prevention, treatment, diagnosis and prognosis of an invasive disease
PL1907420T3 (pl) * 2005-07-21 2017-09-29 Modiquest B.V. Pleksyna D1 jako obiekt docelowy do diagnozowania i leczenia guza

Also Published As

Publication number Publication date
US20090181035A1 (en) 2009-07-16
WO2009089461A1 (en) 2009-07-16
TW200934512A (en) 2009-08-16
AR070134A1 (es) 2010-03-17

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