PE20080608A1 - Compuestos quimicos - Google Patents
Compuestos quimicosInfo
- Publication number
- PE20080608A1 PE20080608A1 PE2007001107A PE2007001107A PE20080608A1 PE 20080608 A1 PE20080608 A1 PE 20080608A1 PE 2007001107 A PE2007001107 A PE 2007001107A PE 2007001107 A PE2007001107 A PE 2007001107A PE 20080608 A1 PE20080608 A1 PE 20080608A1
- Authority
- PE
- Peru
- Prior art keywords
- nitro
- amino
- methyl
- halo
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
SE REFIERE A UN COMPUESTO DE FORMULA I, DONDE R1 ES H, HALO, NITRO, ENTRE OTROS; R2 ES H, NITRO, HIDROXI, HALO, CIANO, ENTRE OTROS; R3 ES H, NITRO, HIDROXI, ALQUILO C1-C4, ENTRE OTROS; W ES -O-, -NR7, CR8R9; ANILLO A ES CARBOCICLICO, HETEROCICLILO, ENTRE OTROS; R4 Y R5 SON CADA UNO ES H, ALQUILO C1-C6, AZIDO, AMINO, ENTRE OTROS; R6 ES AZIDO, HALO, NITRO, CIANO, HIDROXI, TRIFLUOROMETOXI, AMINO, MERCAPTO, SULFAMOILO, ENTRE OTROS; m ES 0-4; R7, R8 Y R9 SON CADA UNO H, ALQUILO C1-C4. SON COMPUESTOS PREFERIDOS: 2-(10-{[(3,4-DICLORO-5-METIL-1H-PIRROL-2-IL)CARBONIL]AMINO}-1,4-DIOXA-7-AZASPIRO[4,5]DEC-7-IL)-1,3-TIAZOL-5-CARBOXILATO DE METILO; 4-ACETIL-2-(10-{[(3,4-DICLORO-5-METIL-1H-PIRROL-2-IL)CARBONIL]AMINO}-1,4-DIOXA-7-AZASPIRO[4,5]DEC-7-IL)-1,3-TIAZOL-5-CARBOXILATO DE METILO; ENTRE OTROS. REFERIDA TAMBIEN A UNA COMPOSICION FARMACEUTICA. DICHOS COMPUESTOS SON INHIBIDORES DE ADN GIRASA Y/O TOPOISOMERASA IV UTILES EN EL TRATAMIENTO DE INFECCIONES BACTERIANAS
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US82274706P | 2006-08-17 | 2006-08-17 | |
US82292306P | 2006-08-18 | 2006-08-18 | |
US89015107P | 2007-02-15 | 2007-02-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20080608A1 true PE20080608A1 (es) | 2008-08-01 |
Family
ID=38705101
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2007001107A PE20080608A1 (es) | 2006-08-17 | 2007-08-16 | Compuestos quimicos |
Country Status (9)
Country | Link |
---|---|
US (1) | US20100286181A1 (es) |
EP (1) | EP2064209A1 (es) |
JP (1) | JP2010500987A (es) |
AR (1) | AR063690A1 (es) |
CL (1) | CL2007002376A1 (es) |
PE (1) | PE20080608A1 (es) |
TW (1) | TW200819437A (es) |
UY (1) | UY30544A1 (es) |
WO (1) | WO2008020222A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1853586B1 (en) | 2005-02-18 | 2013-07-24 | AstraZeneca AB | Antibacterial piperidine derivatives |
TW200906412A (en) * | 2007-06-12 | 2009-02-16 | Astrazeneca Ab | Piperidine compounds and uses thereof |
US20120108565A1 (en) * | 2008-07-30 | 2012-05-03 | Lalima Sharma | Pyrrole carboxylic acid derivatives as antibacterial agents |
JP2010209058A (ja) * | 2008-09-29 | 2010-09-24 | Sumitomo Chemical Co Ltd | 1−置換−トランス−4−(置換アミノ)ピペリジン−3−オールの製造方法 |
US8071605B2 (en) * | 2008-12-12 | 2011-12-06 | Astrazeneca Ab | Piperidine compounds for use in the treatment of bacterial infections |
TW201026694A (en) * | 2008-12-12 | 2010-07-16 | Astrazeneca Ab | Compound 468 |
AR077971A1 (es) | 2009-08-26 | 2011-10-05 | Astrazeneca Ab | Derivados heterociclicos de urea y metodos de uso de los mismos |
EP3092236B1 (en) * | 2014-01-06 | 2020-08-26 | Rhizen Pharmaceuticals S.A. | Novel glutaminase inhibitors |
US10399968B2 (en) | 2015-09-30 | 2019-09-03 | Daiichi Sankyo Company, Limited | Hydroxyalkyl thiadiazole derivatives |
WO2018169092A1 (en) | 2017-03-14 | 2018-09-20 | Daiichi Sankyo Company, Limited | N-phosphonoxymethyl prodrugs of hydroxyalkyl thiadiazole derivatives |
US20210070747A1 (en) | 2017-03-24 | 2021-03-11 | Taisho Pharmaceutical Co., Ltd. | 2(1h)-quinolinone derivative |
EP3847172A1 (en) | 2018-09-03 | 2021-07-14 | Univerza v Ljubljani | New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria |
CN111606827B (zh) * | 2020-06-23 | 2022-10-25 | 内蒙古京东药业有限公司 | 一种制备依度沙班手性胺中间体的方法 |
WO2022129327A1 (en) | 2020-12-17 | 2022-06-23 | Univerza V Ljubljani | New n-phenylpyrrolamide inhibitors of dna gyrase and topoisomerase iv with antibacterial activity |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200526626A (en) * | 2003-09-13 | 2005-08-16 | Astrazeneca Ab | Chemical compounds |
EP1797084A1 (en) * | 2004-09-20 | 2007-06-20 | 4Sc Ag | NOVEL HETEROCYCLIC NF-kB INHIBITORS |
EP1853586B1 (en) * | 2005-02-18 | 2013-07-24 | AstraZeneca AB | Antibacterial piperidine derivatives |
-
2007
- 2007-08-10 TW TW096129768A patent/TW200819437A/zh unknown
- 2007-08-16 WO PCT/GB2007/003134 patent/WO2008020222A1/en active Application Filing
- 2007-08-16 CL CL200702376A patent/CL2007002376A1/es unknown
- 2007-08-16 EP EP07789248A patent/EP2064209A1/en not_active Withdrawn
- 2007-08-16 UY UY30544A patent/UY30544A1/es unknown
- 2007-08-16 PE PE2007001107A patent/PE20080608A1/es not_active Application Discontinuation
- 2007-08-16 US US12/377,785 patent/US20100286181A1/en not_active Abandoned
- 2007-08-16 JP JP2009524234A patent/JP2010500987A/ja active Pending
- 2007-08-16 AR ARP070103650A patent/AR063690A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
CL2007002376A1 (es) | 2008-04-04 |
US20100286181A1 (en) | 2010-11-11 |
AR063690A1 (es) | 2009-02-11 |
UY30544A1 (es) | 2008-03-31 |
JP2010500987A (ja) | 2010-01-14 |
TW200819437A (en) | 2008-05-01 |
EP2064209A1 (en) | 2009-06-03 |
WO2008020222A1 (en) | 2008-02-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20080608A1 (es) | Compuestos quimicos | |
PE20070793A1 (es) | Compuestos triciclicos que contienen nitrogeno como agentes antibacterianos | |
PE20090648A1 (es) | Compuestos para el tratamiento de la hepatitis c | |
PE20091573A1 (es) | Derivados heterociclicos de urea como inhibidores de adn girasa y/o topoisomerasa | |
PE20081583A1 (es) | Agentes antibacterianos derivados de compuestos carbonilamino | |
PE20090601A1 (es) | Derivados de piridin-il-oxi-piridinas como inhibidores de alk5 | |
AR074608A1 (es) | Derivados de 2-(piperidin-1-il)-4-heterociclil-tiazol-5-carboxilico para infecciones bacterianas | |
PE20060691A1 (es) | Serinamidas sustituidas por benzoilo | |
PE20121157A1 (es) | Compuestos heterociclicos como inhibidores de proteasas serinas | |
PE20030062A1 (es) | Derivados aralquilsulfonil-3-(pirrol-2-ilmetiliden)-2-indolinona como inhibidores de quinasas | |
PE20090276A1 (es) | Compuestos derivados de imidazoquinolina como moduladores de tlr7 | |
PE20120693A1 (es) | Compuestos heterociclos como moduladores de la piruvato cinasa m2 (pkm2) | |
PE20120635A1 (es) | Dihidropirazolonas sustituidas como inhibidores de hif-propil-4-hidroxilasas | |
PE20070814A1 (es) | Compuestos derivados de 2-carboxitiofeno como inhibidores de la polimerasa del virus de la hepatitis c (hcv) | |
PE20070367A1 (es) | Compuestos de espiropiperidina como inhibidores de la enzima beta secretasa | |
TW200745117A (en) | Macrocylic inhibitors of hepatitis C virus | |
MX2007007428A (es) | Compuestos heterociclicos, antagonistas de ccr2b. | |
GT200400092A (es) | Preparacion y uso de derivados de alquilarilo para el tratamiento de la obesidad | |
PE20090511A1 (es) | Imidazopiridinonas | |
PE20071177A1 (es) | Derivados de 3,5-piridina como inhibidores de renina | |
MY173930A (en) | Crystalline solvates and complexes of (is)-1,5-anhydro-1-c-(3-((phenyl)methyl)phenyl)-d-glucitol derivatives with amino acids as sglt2 inhibitors for the treatment of diabetes | |
CO6270320A2 (es) | Derivados de piperidina utiles como antagonistas del receptor orexina | |
AR057072A1 (es) | Compuestos quimicos derivados de 2-azetidinona, formulacion farmaceutica y un proceso de preparacion del compuesto | |
AR074435A1 (es) | Derivados de 1,3-benzotiazol, medicamentos que los contienen y uso de los mismos en el tratamiento del cancer. | |
PE20081753A1 (es) | Compuestos y composiciones como inhibidores de la proteasa activadora de canal |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application declared void or lapsed |