PE20001095A1 - Composicion y metodo para tratar enfermedades alergicas - Google Patents

Composicion y metodo para tratar enfermedades alergicas

Info

Publication number
PE20001095A1
PE20001095A1 PE1999001013A PE00101399A PE20001095A1 PE 20001095 A1 PE20001095 A1 PE 20001095A1 PE 1999001013 A PE1999001013 A PE 1999001013A PE 00101399 A PE00101399 A PE 00101399A PE 20001095 A1 PE20001095 A1 PE 20001095A1
Authority
PE
Peru
Prior art keywords
alkyl
heteroaryl
aryl
conr6r7
nr6r7
Prior art date
Application number
PE1999001013A
Other languages
English (en)
Inventor
Neng-Yang Shih
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of PE20001095A1 publication Critical patent/PE20001095A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A UNA COMBINACION FARMACEUTICA QUE COMPRENDE: a)1mg A 1OOOmg POR DOSIS UNITARIA DE UN ANTAGONISTA DE LA NEUROQUININA DE FORMULA I, DONDE Z ES EL GRUPO a O b; B ES OR2, NR6COR2, CONR6R7 O NR2CONR6R7; m ES 0-1, P Y Q SON R5-ARILO, R5-HETEROARILO; Y ES H, CR2R3CO2R6, CR2R3CONR6R7 o CR2R3NR6COR2; a Y b SON 0-2; Q Y P PUEDEN SER IGUALES O DIFERENTES; A ES =N-OR1, =N-NR2R3, =CR1R2; X ES O, NR6, N(R6)CO, CONR6; T ES R4-ARILO, R4-HETEROARILO, R4-CICLOALQUILO, R2-CICLOALQUILO; R1 ES H, ALQUILO C1-C6 o (CH2)n-G; n ES 1-6; G ES H, R4-ARILO, R4-HETEROARILO, COR6, CO2R6, CONR6R7, CN, OCOR6, SO3R2, ENTRE OTROS; R2 Y R3 SON H, ALQUILO C1-C6; R4 Y R5 SON OR2, OC(O)R2, OC(O)NR6R7, ALQUILO C1-C6, H, HALOGENO, CF3, C2F5, OCF3; R6 Y R7 SON H, ALQUILO C1-C6, CUANDO R6 Y R7 SON NR6R7 FORMAN UN ANILLO C5-C6 CON O, S, NR2, ENTRE OTROS; b)DE 2mg A 500mg DE UN ANTAGONISTA DE LEUCOTRIENO TAL COMO MONTELUKAST, PRANLUKAST, ZAFIRLUKAST; c)2mg A 5OOmg DE UN INHIBIDOR DE 5-LIPOOXIGENASA TAL COMO ZILEUTON, ATRELUTON; d)UNO O MAS PORTADORES FARMACEUTICAMENTE ACEPTABLES, UN DESCONGESTIVO, UN SUPRESOR DE LA TOSO O UN EXPECTORANTE. LA COMBINACION FARMACEUTICA ES UTIL PARA EL TRATAMIENTO DEL ASMA, RINITIS ALERGICA, ESTORNUDOS
PE1999001013A 1998-10-09 1999-10-06 Composicion y metodo para tratar enfermedades alergicas PE20001095A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16960998A 1998-10-09 1998-10-09

Publications (1)

Publication Number Publication Date
PE20001095A1 true PE20001095A1 (es) 2000-10-31

Family

ID=22616408

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1999001013A PE20001095A1 (es) 1998-10-09 1999-10-06 Composicion y metodo para tratar enfermedades alergicas

Country Status (9)

Country Link
EP (1) EP1119372A1 (es)
JP (1) JP2002527406A (es)
CN (1) CN1329505A (es)
AR (1) AR020741A1 (es)
AU (1) AU6391199A (es)
CA (1) CA2346228A1 (es)
CO (1) CO5140080A1 (es)
PE (1) PE20001095A1 (es)
WO (1) WO2000021564A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004229507B2 (en) * 2003-04-15 2008-12-18 Merck Frosst Canada & Co. Polymorphic form of montelukast sodium
JP3983272B2 (ja) * 2004-07-14 2007-09-26 有限会社 炎症研究所 腫瘍転移の抑制方法
BRPI0807972A2 (pt) 2007-01-24 2014-06-10 Glaxo Group Ltd Composições farmacêuticas compreendendo 3,5-diamino-6-(2,3-diclofenil)-l,2,4-triazina ou r(-)-2,4-diamino-5-(2,3-diclorofenil)-6-fluorometilpirim idina e uma nk1

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9415997D0 (en) * 1994-08-08 1994-09-28 Merck Sharp & Dohme Therapeutic agents
EP2301562B1 (en) * 1994-12-12 2013-04-17 Omeros Corporation Irrigation solution and method for inhibition of pain, inflammation and spasm
GB9521781D0 (en) * 1995-10-24 1996-01-03 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
CO5140080A1 (es) 2002-03-22
AR020741A1 (es) 2002-05-29
EP1119372A1 (en) 2001-08-01
CN1329505A (zh) 2002-01-02
CA2346228A1 (en) 2000-04-20
AU6391199A (en) 2000-05-01
WO2000021564A1 (en) 2000-04-20
JP2002527406A (ja) 2002-08-27

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Legal Events

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