PE132299A1 - Antibioticos de quinolona magnesica - Google Patents

Antibioticos de quinolona magnesica

Info

Publication number
PE132299A1
PE132299A1 PE1998001095A PE00109598A PE132299A1 PE 132299 A1 PE132299 A1 PE 132299A1 PE 1998001095 A PE1998001095 A PE 1998001095A PE 00109598 A PE00109598 A PE 00109598A PE 132299 A1 PE132299 A1 PE 132299A1
Authority
PE
Peru
Prior art keywords
quinolone
solution
magnesica
antibiotics
compound
Prior art date
Application number
PE1998001095A
Other languages
English (en)
Inventor
Karen Barsuhn
Ching-Chiang Su
Rodney K Frank
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of PE132299A1 publication Critical patent/PE132299A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

CARACTERIZADA POR COMPRENDER UNA SOLUCION DE a)UNA QUINOLONA DE FORMULA I, SIENDO DE PREFERENCIA EL ACIDO 3R,1S-1-CICLOPROPIL-7-(3-(1-(METILAMINO)ETIL)-1-PIRROLIDINIL)-6-FLUORO-1,4-DIHIDRO-8-METOXI-4-OXO-3-QUINOLINCARBOXILICO Y SUS ESTERES ALQUILO C1-C4; b)IONES MAGNESIO; LA PROPORCION DE LOS COMPONENTES DE LA SOLUCION ES DE 1:4 A 3:1 PARTES DE IONES MAGNESIO A COMPUESTO; EL pH DE LA SOLUCION ES ENTRE 6-8. TAMBIEN SE REFIERE A UN PROCEDIMIENTO PARA LA PREPARACION. EL COMPUESTO I PUEDE SER UTIL PARA EL TRATAMIENTO DE UNA INFECCION BACTERIANA
PE1998001095A 1997-12-05 1998-11-13 Antibioticos de quinolona magnesica PE132299A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6782997P 1997-12-05 1997-12-05

Publications (1)

Publication Number Publication Date
PE132299A1 true PE132299A1 (es) 1999-12-21

Family

ID=22078690

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1998001095A PE132299A1 (es) 1997-12-05 1998-11-13 Antibioticos de quinolona magnesica

Country Status (8)

Country Link
US (1) US6288080B1 (es)
AR (1) AR017812A1 (es)
AU (1) AU1796799A (es)
CO (1) CO5011059A1 (es)
ID (1) ID21415A (es)
PE (1) PE132299A1 (es)
WO (1) WO1999029322A1 (es)
ZA (1) ZA9810994B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030171340A1 (en) * 2002-02-07 2003-09-11 Jenefir Isbister Methods of disease treatment using metal-complexed tetracycline antibiotics
KR20070029280A (ko) * 2004-07-02 2007-03-13 다이이찌 세이야꾸 가부시기가이샤 퀴놀론 함유 의약 조성물
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
DE102006010643A1 (de) 2006-03-08 2007-09-13 Bayer Healthcare Aktiengesellschaft Arzneimittel enthaltend Fluorchinolone
JP2012505223A (ja) 2008-10-07 2012-03-01 エムペックス・ファーマシューティカルズ・インコーポレーテッド 薬物動態の改善のためのエアゾールフルオロキノロン配合物
ES2809177T3 (es) 2008-10-07 2021-03-03 Horizon Orphan Llc Inhalación de levofloxacino para reducir la inflamación pulmonar
CA2773033C (en) 2009-09-04 2016-10-11 Mpex Pharmaceuticals, Inc. Use of aerosolized levofloxacin for treating cystic fibrosis
US10617684B2 (en) 2015-06-02 2020-04-14 Kyorin Pharmaceutical Co., Ltd. Aqueous drug
WO2016195021A1 (ja) 2015-06-02 2016-12-08 杏林製薬株式会社 水性液剤
EP3305295A4 (en) * 2015-06-02 2019-02-20 Kyorin Pharmaceutical Co., Ltd. AQUEOUS MEDICINE
UA124124C2 (uk) 2017-02-13 2021-07-21 Баєр Енімал Хелс Гмбх Рідка композиція, що містить прадофлоксацин

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
DE3517709A1 (de) 1985-01-05 1986-07-10 Bayer Ag Basische zubereitungen von chinoloncarbonsaeuren
DE3635062A1 (de) 1986-10-15 1988-04-21 Bayer Ag Neue metallsalze von 1-cyclopropyl-chinoloncarbonsaeuren und diese enthaltende arzneimittel
DE3902079A1 (de) 1988-04-15 1989-10-26 Bayer Ag I.m. injektionsformen von gyrase-inhibitoren
US5225413A (en) 1988-09-16 1993-07-06 Bayer-Aktiengesellschaft pH-neutral aqueous solutions of quinolone-carboxylic acids
JP2832535B2 (ja) * 1989-04-04 1998-12-09 富山化学工業株式会社 キノロンカルボン酸またはその塩の可溶化法
JP3153549B2 (ja) 1989-12-29 2001-04-09 アボツト・ラボラトリーズ キノロンカルボン酸―金属イオン―酸錯体
US5084276A (en) 1990-01-05 1992-01-28 Abbott Laboratories Quinolone carboxylic acid compositions with polymeric additive to reduce vein irritation
FR2665635A1 (fr) 1990-08-10 1992-02-14 Merck Sharp & Dohme Composition pharmaceutique fluide a base d'un complexe metallique et son procede de preparation.
US5258528A (en) * 1990-11-30 1993-11-02 Warner-Lambert Company Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group
GB9118183D0 (en) 1991-08-23 1991-10-09 Solanki Kishor K Imaging of infections
ES2111083T3 (es) 1991-09-17 1998-03-01 Alcon Lab Inc Composiciones que contienen antibioticos de quinolona y poli(sulfonato de estireno).
US5290794A (en) 1992-10-27 1994-03-01 Warner Lambert Co. Soluble calcium lactate antibacterial complexes as non-irritating parenteral forms
US5363155A (en) * 1993-02-18 1994-11-08 Ehud Urinowski Eye examination apparatus and accessory therefor
US5519843A (en) 1993-03-15 1996-05-21 M-Systems Flash memory system providing both BIOS and user storage capability
IL109626A0 (en) 1993-05-15 1994-08-26 Abbott Lab Stable quinolone and naphthydridine premix formulations
IL124454A (en) * 1995-12-21 2003-10-31 Pfizer Injectable danofloxacin formulations
EP0898477B1 (en) * 1996-05-10 2002-12-18 PHARMACIA & UPJOHN COMPANY Topical administration of premafloxacin for the treatment of systemic bacterial diseases

Also Published As

Publication number Publication date
AR017812A1 (es) 2001-10-24
CO5011059A1 (es) 2001-02-28
US6288080B1 (en) 2001-09-11
ID21415A (id) 1999-06-10
AU1796799A (en) 1999-06-28
WO1999029322A1 (en) 1999-06-17
ZA9810994B (en) 2000-06-01

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