PA8657801A1 - TRICYCLE AMINALCOHOLES, PROCEDURES FOR THEIR PREPARATION - Google Patents

TRICYCLE AMINALCOHOLES, PROCEDURES FOR THEIR PREPARATION

Info

Publication number
PA8657801A1
PA8657801A1 PA20058657801A PA8657801A PA8657801A1 PA 8657801 A1 PA8657801 A1 PA 8657801A1 PA 20058657801 A PA20058657801 A PA 20058657801A PA 8657801 A PA8657801 A PA 8657801A PA 8657801 A1 PA8657801 A1 PA 8657801A1
Authority
PA
Panama
Prior art keywords
tricycle
procedures
preparation
aminalcoholes
aminoalcoholes
Prior art date
Application number
PA20058657801A
Other languages
Spanish (es)
Inventor
Konrad Krolikiewicz
Heike Schaecke
Markus Berger
Hartmut Rehwinkel
Norbert Schmees
Anne Mengel
Stefan Baurle
Danja Grossbach
David Voigtlaender
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PA8657801A1 publication Critical patent/PA8657801A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/74—Quinazolines; Hydrogenated quinazolines with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to ring carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

LA INVENCION SE REFIERE A AMINOALCOHOLES TRICICLICOS DE LA FORMULA GENERAL I A PROCEDIMIENTOS PARA SU PREPARACION Y A SU USO COMO INHIBIDORES DE LA INFLAMACION.THE INVENTION REFERS TO TRICYCLE AMINOALCOHOLES OF THE GENERAL FORMULA I TO PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS INFLAMMATION INHIBITORS.

PA20058657801A 2004-12-22 2005-12-22 TRICYCLE AMINALCOHOLES, PROCEDURES FOR THEIR PREPARATION PA8657801A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004063227A DE102004063227A1 (en) 2004-12-22 2004-12-22 Tricylic amino alcohols, process for their preparation and their use as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
PA8657801A1 true PA8657801A1 (en) 2006-12-07

Family

ID=36250953

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20058657801A PA8657801A1 (en) 2004-12-22 2005-12-22 TRICYCLE AMINALCOHOLES, PROCEDURES FOR THEIR PREPARATION

Country Status (14)

Country Link
JP (1) JP2008524300A (en)
KR (1) KR20070089948A (en)
CN (1) CN101087780A (en)
AR (1) AR055016A1 (en)
AU (1) AU2005318354A1 (en)
BR (1) BRPI0519710A2 (en)
CA (1) CA2586973A1 (en)
DE (1) DE102004063227A1 (en)
GT (1) GT200500385A (en)
IL (1) IL183060A0 (en)
MX (1) MX2007007420A (en)
PA (1) PA8657801A1 (en)
PE (1) PE20061197A1 (en)
WO (1) WO2006066950A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2539587A1 (en) 2003-10-08 2005-04-21 Schering Aktiengesellschaft 1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiphlogistics
US7662821B2 (en) 2003-10-08 2010-02-16 Bayer Schering Pharma Ag Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
US7638515B2 (en) 2003-10-08 2009-12-29 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
US20080153859A1 (en) 2004-04-05 2008-06-26 Hartmut Rehwinkel Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
US7297700B2 (en) 2005-03-24 2007-11-20 Renovis, Inc. Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
EP1834948A1 (en) 2006-03-15 2007-09-19 Bayer Schering Pharma Aktiengesellschaft Tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiinflammatory drugs
TWI464148B (en) 2006-03-16 2014-12-11 Evotec Us Inc Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
EP1917963A1 (en) * 2006-10-31 2008-05-07 Bayer Schering Pharma Aktiengesellschaft Cyclic phenyl-substituted indazols, a process for their production and their use as anti-inflammatory agents
EP2072509A1 (en) 2007-12-18 2009-06-24 Bayer Schering Pharma Aktiengesellschaft 1-Aryl-1H-quinoline-2-ones: process for their production and their use as anti-inflammatory agents
JP6250561B2 (en) 2012-02-08 2017-12-20 サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． Heteroaryl compounds and methods for their use
MA45857A (en) 2016-07-29 2021-05-19 Sunovion Pharmaceuticals Inc COMPOUNDS AND COMPOSITIONS, AND ASSOCIATED USES
SG11201900687VA (en) 2016-07-29 2019-02-27 Sunovion Pharmaceuticals Inc Compounds and compositions and uses thereof
AU2018312559B2 (en) 2017-08-02 2022-06-02 Pgi Drug Discovery Llc Isochroman compounds and uses thereof
AU2020236225A1 (en) 2019-03-14 2021-09-16 Sunovion Pharmaceuticals Inc. Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof
KR102462991B1 (en) * 2020-11-02 2022-11-04 한국해양과학기술원 Compound from a Antarctic-Derived Fungal Strains Acremonium sp. SF-7394 and Composition for Anti-Inflammation, Anticancer or Anti-Diabetes Comprising the Same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10038639A1 (en) * 2000-07-28 2002-02-21 Schering Ag New and known N-aryl 2-hydroxy-omega-arylalkanamide derivatives, useful e.g. for treating inflammatory diseases such as rheumatism
NZ535889A (en) * 2002-03-26 2006-03-31 Boehringer Ingelheim Pharma Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
DE10215316C1 (en) * 2002-04-02 2003-12-18 Schering Ag Quinoline and isoquinoline derivatives, a pharmaceutical agent and their use as anti-inflammatory agents
CA2539587A1 (en) * 2003-10-08 2005-04-21 Schering Aktiengesellschaft 1-amino-2-oxy-substituted tetrahydronaphtalene derivatives, methods for the production thereof, and their use as antiphlogistics
GB0418045D0 (en) * 2004-08-12 2004-09-15 Glaxo Group Ltd Compounds
DE102004044680B3 (en) * 2004-09-09 2006-06-08 Schering Ag Alkylidene tetrahydronaphthalene derivatives, process for their preparation and their use as anti-inflammatory agents and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE102004063227A1 (en) 2006-07-06
WO2006066950A3 (en) 2006-08-17
GT200500385A (en) 2006-08-03
MX2007007420A (en) 2007-07-17
WO2006066950A2 (en) 2006-06-29
KR20070089948A (en) 2007-09-04
AR055016A1 (en) 2007-08-01
IL183060A0 (en) 2007-09-20
BRPI0519710A2 (en) 2009-03-10
AU2005318354A1 (en) 2006-06-29
CA2586973A1 (en) 2006-06-29
CN101087780A (en) 2007-12-12
PE20061197A1 (en) 2006-12-07
JP2008524300A (en) 2008-07-10

Similar Documents

Publication Publication Date Title
PA8657801A1 (en) TRICYCLE AMINALCOHOLES, PROCEDURES FOR THEIR PREPARATION
CR11373A (en) TIENOPIRIMIDINE AND PIRAZOLOPIRIMIDINE COMPOUNDS AND THEIR USE AS INHIBITORS OF mTOR CINASA AND PI3 CINASA
CR10328A (en) ORGANIC COMPOUNDS
HN2008001191A (en) SUBSTITUTED BICYCOLACTAM COMPOUNDS
GT201000023A (en) NEW DERIVATIVES OF 6-TRIALZOLOPIRIDACINA-SULFANIL BENZOTIAZOL AND BENCIMIDAZOL, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICATIONS, PHARMACEUTICAL COMPOSITIONS AND NEW MAIN USE AS MET INHIBITORS.
ECSP077271A (en) PIRIMIDINE DERIVATIVES
CR11241A (en) PIRAZOL COMPOUNDS AND ITS USE AS RAF INHIBITORS
HN2003000285A (en) NEW ESPIROCONDENSED QUINAZOLINONES AND ITS USE AS PHOSPHODIESTERASE INHIBITORS
UY30748A1 (en) NEW COMPOUNDS
NI201000005A (en) CYTOTOXIC AGENTS INCLUDING NEW TOMAIMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE.
ECSP077259A (en) PIRIMIDINE DERIVATIVES
CR9786A (en) BENCIMIDAZOL-THIOPHEN COMPOUNDS
ECSP088925A (en) SIPROCYCLIC NITRILS AS PROTEASA INHIBITORS
ECSP088740A (en) TETRAHYDRONAFTALINE DERIVATIVES, PROCEDURES TO PREPARE THEM AND THEIR USE AS ANTI-INFLAMMATORIES
UY29434A1 (en) DERIVATIVES OF TETRAHYDRONAFTALINE, PROCEDURES FOR THEIR PREPARATION AND ITS USE AS INFLAMMATION INHIBITORS
PA8644701A1 (en) DERIVATIVES OF ALQUILIDEN-TETRAHIDRONAFTALENO, PROCEDURE FOR ITS PREPARATION AND ITS USE AS ANTI-INFLAMMATORIES
UY30801A1 (en) CALCILITICAL COMPOUNDS
CR9058A (en) DERIVATIVES OF INDOL AS INHIBITORS OF THE SOLUBLE CYCLING ADENYLATE
PA8668901A1 (en) TETRAHYDRONAFTALINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND ITS USE AS ANTI-INFLAMMATORIES
UY31139A1 (en) CRYSTALLINE FORMS OF 3- (2R-TETRAHIDROFURIL-METHYL) -2-THIOXANTINE
UY30235A1 (en) INHIBITORS OF THE SOLUBLE CYCLING ADENYLATE
PA8666801A1 (en) DERIVATIVE OF 5H-BENSOCICLOHEPTENO, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY
CR9578A (en) INHIBITORS OF THE SOLUBLE CYCLING ADENYLATE
UY30237A1 (en) INHIBITORS OF THE SOLUBLE CYCLING ADENYLATE
DOP2007000059A (en) INHIBITORS OF THE SOLUBLE CYCLING ADENYLATE