PA8666801A1 - DERIVATIVE OF 5H-BENSOCICLOHEPTENO, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY - Google Patents

DERIVATIVE OF 5H-BENSOCICLOHEPTENO, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY

Info

Publication number
PA8666801A1
PA8666801A1 PA20068666801A PA8666801A PA8666801A1 PA 8666801 A1 PA8666801 A1 PA 8666801A1 PA 20068666801 A PA20068666801 A PA 20068666801A PA 8666801 A PA8666801 A PA 8666801A PA 8666801 A1 PA8666801 A1 PA 8666801A1
Authority
PA
Panama
Prior art keywords
inflammatory
preparation
bensociclohepteno
derivative
procedure
Prior art date
Application number
PA20068666801A
Other languages
Spanish (es)
Inventor
Duy Nguyen
Markus Berger
Hartmut Rehwinkel
Heike Schaecke
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of PA8666801A1 publication Critical patent/PA8666801A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

LA INVENCION SE REFIERE A DERIVADOS DE 5H-BENZOCICLOHEPTENO POLISUSTITUIDOS DE LA FORMULA (I) A PROCEDIMIENTOS PARA SU PREPARACION Y A SU USO COMO ANTIINFLAMATORIOS.THE INVENTION REFERS TO DERIVATIVES OF 5H-BENZOCICLOHEPTENO POLISUSTITUIDOS OF FORMULA (I) PROCEDURES FOR PREPARATION AND FOR USE AS ANTI-INFLAMMATORY.

PA20068666801A 2005-03-22 2006-03-21 DERIVATIVE OF 5H-BENSOCICLOHEPTENO, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY PA8666801A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005014090A DE102005014090A1 (en) 2005-03-22 2005-03-22 5H-Benzocycloheptender derivatives, process for their preparation and their use as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
PA8666801A1 true PA8666801A1 (en) 2006-09-22

Family

ID=36589218

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20068666801A PA8666801A1 (en) 2005-03-22 2006-03-21 DERIVATIVE OF 5H-BENSOCICLOHEPTENO, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY

Country Status (13)

Country Link
EP (1) EP1863765A1 (en)
JP (1) JP2008534462A (en)
CN (1) CN101146773A (en)
AR (1) AR053189A1 (en)
CA (1) CA2598969A1 (en)
DE (1) DE102005014090A1 (en)
DO (1) DOP2006000065A (en)
GT (1) GT200600124A (en)
PA (1) PA8666801A1 (en)
PE (1) PE20061350A1 (en)
TW (1) TW200700389A (en)
UY (1) UY29435A1 (en)
WO (1) WO2006100099A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE057892T2 (en) * 2016-02-15 2022-06-28 Sanofi Sa Processes and intermediates for the preparation of novel substituted 6,7-dihydro-5h-benzo[7]annulene compounds
CN107118173B (en) * 2017-07-12 2019-10-29 阿里生物新材料（常州）有限公司 A kind of cycloheptatriene and oxazine compound and preparation method thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8402275A (en) * 1974-08-26 1977-02-17 Takeda Chemical Industries Ltd Benzocycloheptene derivatives
PT87487B (en) * 1987-05-15 1992-09-30 Schering Corp PROCESS FOR THE PREPARATION OF NAFTALENE, BENZOXEPIN, BENZAZEPINE AND BENZOCYCLOHEPTEN DERIVATIVES
WO1989000570A1 (en) * 1987-07-16 1989-01-26 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazols
WO1999005107A1 (en) * 1997-07-25 1999-02-04 Smithkline Beecham Corporation Vitronectin receptor antagonist
BRPI0407304A (en) * 2003-02-07 2006-01-10 Warner Lambert Co Antibacterial agents

Also Published As

Publication number Publication date
WO2006100099A1 (en) 2006-09-28
AR053189A1 (en) 2007-04-25
PE20061350A1 (en) 2006-12-20
CA2598969A1 (en) 2006-09-28
GT200600124A (en) 2007-01-03
CN101146773A (en) 2008-03-19
EP1863765A1 (en) 2007-12-12
TW200700389A (en) 2007-01-01
DE102005014090A1 (en) 2006-09-28
JP2008534462A (en) 2008-08-28
UY29435A1 (en) 2006-10-02
DOP2006000065A (en) 2006-10-15

Similar Documents

Publication Publication Date Title
PA8657801A1 (en) TRICYCLE AMINALCOHOLES, PROCEDURES FOR THEIR PREPARATION
ECSP077271A (en) PIRIMIDINE DERIVATIVES
ECSP077259A (en) PIRIMIDINE DERIVATIVES
CR11373A (en) TIENOPIRIMIDINE AND PIRAZOLOPIRIMIDINE COMPOUNDS AND THEIR USE AS INHIBITORS OF mTOR CINASA AND PI3 CINASA
CR11241A (en) PIRAZOL COMPOUNDS AND ITS USE AS RAF INHIBITORS
DOP2011000171A (en) ORGANIC COMPOUNDS
GT201000023A (en) NEW DERIVATIVES OF 6-TRIALZOLOPIRIDACINA-SULFANIL BENZOTIAZOL AND BENCIMIDAZOL, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICATIONS, PHARMACEUTICAL COMPOSITIONS AND NEW MAIN USE AS MET INHIBITORS.
HN2008001393A (en) DERIVATIVES OF 1,2,4,5- TETRAHIDRO -3H- BENZAZEPINAS, ITS PREPARATION PROCEDURE AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
ECSP088740A (en) TETRAHYDRONAFTALINE DERIVATIVES, PROCEDURES TO PREPARE THEM AND THEIR USE AS ANTI-INFLAMMATORIES
UY29434A1 (en) DERIVATIVES OF TETRAHYDRONAFTALINE, PROCEDURES FOR THEIR PREPARATION AND ITS USE AS INFLAMMATION INHIBITORS
PA8644701A1 (en) DERIVATIVES OF ALQUILIDEN-TETRAHIDRONAFTALENO, PROCEDURE FOR ITS PREPARATION AND ITS USE AS ANTI-INFLAMMATORIES
DOP2006000024A (en) THIAZOLIDINONES, ITS PREPARATION AND ITS USE AS A MEDICINAL PRODUCT
CR11392A (en) PIRAZOL DERIVATIVES AS 5-LO INHIBITORS
CR9058A (en) DERIVATIVES OF INDOL AS INHIBITORS OF THE SOLUBLE CYCLING ADENYLATE
GT200600153A (en) TETRAHYDRONAFTALINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND ITS USE AS ANTI-INFLAMMATORY.
PA8666801A1 (en) DERIVATIVE OF 5H-BENSOCICLOHEPTENO, PROCEDURE FOR PREPARATION AND USE AS ANTI-INFLAMMATORY
CR9578A (en) INHIBITORS OF THE SOLUBLE CYCLING ADENYLATE
DOP2010000257A (en) COMPOUND (R) -N * 6 * -ETIL-6,7-DIHIDRO-5H-INDENO (5,6-D) TIAZOL-2,6-DIAMINE AND ITS USE AS ANTIPSYCHOTIC
DOP2006000089A (en) TETRAHYDRONAFTALINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND USE AS ANTI-INFLAMMATORY.
UY28907A1 (en) CHROMANOL DERIVATIVES, A PROCEDURE FOR THEIR PREPARATION AND ITS USE AS INFLAMMATION INHIBITORS.
UY29309A1 (en) TRICYCLIC AMINOALCOHOLES, PROCEDURES FOR PREPARATION AND USE AS INFLAMMATION INHIBITORS
CR9107A (en) 5-SUBSTITUTED QUINOLINE AND ISOQUINOLINE DERIVATIVES, A PROCEDURE FOR THEIR PREPARATION AND ITS USE AS INFLAMMATION INHIBITORS
DOP2006000064A (en) TETRAHYDRONAFTALINE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND ITS USE AS INFLAMMATION INHIBITORS
CU23350B7 (en) 2TIO-3,5DICYANO-4-FENIL-6-AMINOPIRIDINAS REPLACED AND ITS USE
DOP2005000275A (en) TRICYCLE AMINOALCOHOLES, PROCEDURES FOR PREPARATION AND USE AS INFLAMMATION INHIBITORS