OA10349A - Processes for the diastereoselective synthesis of nucleosides - Google Patents
Processes for the diastereoselective synthesis of nucleosides Download PDFInfo
- Publication number
- OA10349A OA10349A OA60438A OA60438A OA10349A OA 10349 A OA10349 A OA 10349A OA 60438 A OA60438 A OA 60438A OA 60438 A OA60438 A OA 60438A OA 10349 A OA10349 A OA 10349A
- Authority
- OA
- OAPI
- Prior art keywords
- oxathiolane
- carboxylate
- formula
- menthyl
- cis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D411/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
- C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D497/08—Bridged systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939311709A GB9311709D0 (en) | 1993-06-07 | 1993-06-07 | Stereoselective synthesis of nucleoside analogues using bicycle intermediate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA10349A true OA10349A (en) | 2001-10-18 |
Family
ID=10736757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA60438A OA10349A (en) | 1993-06-07 | 1993-11-19 | Processes for the diastereoselective synthesis of nucleosides |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5763606A (ru) |
| EP (1) | EP0654031B1 (ru) |
| JP (1) | JP3110461B2 (ru) |
| KR (1) | KR100304072B1 (ru) |
| CN (1) | CN1046720C (ru) |
| AT (1) | ATE188215T1 (ru) |
| AU (1) | AU668829B2 (ru) |
| BR (1) | BR9405423A (ru) |
| CA (1) | CA2141029C (ru) |
| DE (1) | DE69422374T2 (ru) |
| DK (1) | DK0654031T3 (ru) |
| ES (1) | ES2139744T3 (ru) |
| FI (1) | FI112078B (ru) |
| GB (1) | GB9311709D0 (ru) |
| HK (1) | HK1008673A1 (ru) |
| HU (1) | HU219199B (ru) |
| NO (1) | NO303449B1 (ru) |
| NZ (1) | NZ267379A (ru) |
| OA (1) | OA10349A (ru) |
| PL (1) | PL180870B1 (ru) |
| RU (1) | RU2139870C1 (ru) |
| WO (1) | WO1994029301A1 (ru) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5684164A (en) * | 1988-04-11 | 1997-11-04 | Biochem Pharma Inc. | Processes for preparing substituted 1,3-oxathiolanes with antiviral properties |
| WO1996012716A1 (en) * | 1994-10-22 | 1996-05-02 | Chong Kun Dang Corp. | Nucleoside derivatives and process for preparing thereof |
| JP4249393B2 (ja) | 1998-08-12 | 2009-04-02 | トライアングル・ファーマシューティカルズ，インコーポレイテッド | １，３−オキサチオランヌクレオチドの製造方法 |
| US6979561B1 (en) | 1998-10-09 | 2005-12-27 | Gilead Sciences, Inc. | Non-homogeneous systems for the resolution of enantiomeric mixtures |
| CA2308559C (en) | 2000-05-16 | 2005-07-26 | Brantford Chemicals Inc. | 1,3-oxathiolan-5-ones useful in the production of antiviral nucleoside analogues |
| CN102911166B (zh) * | 2001-03-01 | 2016-08-17 | 基利得科学公司 | 顺-ftc的多晶型物及其它晶型 |
| ES2308136T3 (es) * | 2003-01-14 | 2008-12-01 | Gilead Sciences, Inc. | Composiciones y procedimientos para la politerapia antiviral. |
| WO2005074654A2 (en) * | 2004-02-03 | 2005-08-18 | Emory University | Methods to manufacture 1,3-dioxolane nucleosides |
| TWI375560B (en) | 2005-06-13 | 2012-11-01 | Gilead Sciences Inc | Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same |
| TWI471145B (zh) | 2005-06-13 | 2015-02-01 | Bristol Myers Squibb & Gilead Sciences Llc | 單一式藥學劑量型 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5047407A (en) * | 1989-02-08 | 1991-09-10 | Iaf Biochem International, Inc. | 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties |
| US5204466A (en) * | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
| GB9009861D0 (en) * | 1990-05-02 | 1990-06-27 | Glaxo Group Ltd | Chemical compounds |
| AU9125991A (en) * | 1990-12-05 | 1992-07-08 | University Of Georgia Research Foundation, Inc., The | Enantiomerically pure beta -l-(-)-1,3-oxathiolane nucleosides |
| ZA923640B (en) * | 1991-05-21 | 1993-02-24 | Iaf Biochem Int | Processes for the diastereoselective synthesis of nucleosides |
| GB9116601D0 (en) * | 1991-08-01 | 1991-09-18 | Iaf Biochem Int | 1,3-oxathiolane nucleoside analogues |
| US5332814A (en) * | 1991-11-12 | 1994-07-26 | Ciba-Geigy Corporation | Process for the preparation of carbacyclic nucleosides, and intermediates |
-
1993
- 1993-06-07 GB GB939311709A patent/GB9311709D0/en active Pending
- 1993-11-19 OA OA60438A patent/OA10349A/en unknown
-
1994
- 1994-06-07 NZ NZ267379A patent/NZ267379A/en not_active IP Right Cessation
- 1994-06-07 KR KR1019950700453A patent/KR100304072B1/ko not_active IP Right Cessation
- 1994-06-07 AU AU69667/94A patent/AU668829B2/en not_active Ceased
- 1994-06-07 EP EP94918252A patent/EP0654031B1/en not_active Expired - Lifetime
- 1994-06-07 US US08/379,644 patent/US5763606A/en not_active Expired - Fee Related
- 1994-06-07 CA CA002141029A patent/CA2141029C/en not_active Expired - Fee Related
- 1994-06-07 RU RU95108553A patent/RU2139870C1/ru not_active IP Right Cessation
- 1994-06-07 DK DK94918252T patent/DK0654031T3/da active
- 1994-06-07 AT AT94918252T patent/ATE188215T1/de not_active IP Right Cessation
- 1994-06-07 DE DE69422374T patent/DE69422374T2/de not_active Expired - Fee Related
- 1994-06-07 CN CN94190356A patent/CN1046720C/zh not_active Expired - Fee Related
- 1994-06-07 PL PL94307350A patent/PL180870B1/pl not_active IP Right Cessation
- 1994-06-07 HU HU9500364A patent/HU219199B/hu not_active IP Right Cessation
- 1994-06-07 BR BR9405423A patent/BR9405423A/pt not_active Application Discontinuation
- 1994-06-07 JP JP07501139A patent/JP3110461B2/ja not_active Expired - Fee Related
- 1994-06-07 WO PCT/CA1994/000311 patent/WO1994029301A1/en active IP Right Grant
- 1994-06-07 ES ES94918252T patent/ES2139744T3/es not_active Expired - Lifetime
-
1995
- 1995-02-06 NO NO950432A patent/NO303449B1/no unknown
- 1995-02-07 FI FI950535A patent/FI112078B/fi active
-
1998
- 1998-07-02 HK HK98108821A patent/HK1008673A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2139744T3 (es) | 2000-02-16 |
| CN1110479A (zh) | 1995-10-18 |
| EP0654031A1 (en) | 1995-05-24 |
| KR100304072B1 (ko) | 2001-11-22 |
| HU219199B (en) | 2001-03-28 |
| JPH08505643A (ja) | 1996-06-18 |
| HU9500364D0 (en) | 1995-05-29 |
| CN1046720C (zh) | 1999-11-24 |
| DE69422374T2 (de) | 2000-06-29 |
| BR9405423A (pt) | 1999-05-25 |
| PL180870B1 (pl) | 2001-04-30 |
| HK1008673A1 (en) | 1999-05-14 |
| RU95108553A (ru) | 1996-11-20 |
| NO950432D0 (no) | 1995-02-06 |
| DE69422374D1 (de) | 2000-02-03 |
| ATE188215T1 (de) | 2000-01-15 |
| HUT73630A (en) | 1996-08-28 |
| AU668829B2 (en) | 1996-05-16 |
| DK0654031T3 (da) | 2000-06-13 |
| US5763606A (en) | 1998-06-09 |
| GB9311709D0 (en) | 1993-07-21 |
| FI112078B (fi) | 2003-10-31 |
| CA2141029A1 (en) | 1994-12-22 |
| NO303449B1 (no) | 1998-07-13 |
| WO1994029301A1 (en) | 1994-12-22 |
| FI950535A (fi) | 1995-02-07 |
| NZ267379A (en) | 1997-04-24 |
| CA2141029C (en) | 2000-07-25 |
| EP0654031B1 (en) | 1999-12-29 |
| RU2139870C1 (ru) | 1999-10-20 |
| NO950432L (no) | 1995-03-13 |
| AU6966794A (en) | 1995-01-03 |
| PL307350A1 (en) | 1995-05-15 |
| JP3110461B2 (ja) | 2000-11-20 |
| FI950535A0 (fi) | 1995-02-07 |
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