OA09242A - 2', 3' Dideoxyribofuranoxide derivatives. - Google Patents
2', 3' Dideoxyribofuranoxide derivatives.Info
- Publication number
- OA09242A OA09242A OA59645A OA59645A OA09242A OA 09242 A OA09242 A OA 09242A OA 59645 A OA59645 A OA 59645A OA 59645 A OA59645 A OA 59645A OA 09242 A OA09242 A OA 09242A
- Authority
- OA
- OAPI
- Prior art keywords
- group
- acylated
- dideoxyribofuranoxide
- derivatives
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878706991A GB8706991D0 (en) | 1987-03-24 | 1987-03-24 | Chemical compounds |
GB878713464A GB8713464D0 (en) | 1987-06-09 | 1987-06-09 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
OA09242A true OA09242A (en) | 1992-06-30 |
Family
ID=26292055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA59645A OA09242A (en) | 1987-03-24 | 1989-09-19 | 2', 3' Dideoxyribofuranoxide derivatives. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0342203B1 (de) |
JP (1) | JPH02503312A (de) |
AT (1) | ATE108183T1 (de) |
AU (1) | AU613026B2 (de) |
DE (1) | DE3850571T2 (de) |
FI (1) | FI93217C (de) |
NZ (1) | NZ223990A (de) |
OA (1) | OA09242A (de) |
WO (1) | WO1988007532A1 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6448392B1 (en) | 1985-03-06 | 2002-09-10 | Chimerix, Inc. | Lipid derivatives of antiviral nucleosides: liposomal incorporation and method of use |
US5223263A (en) * | 1988-07-07 | 1993-06-29 | Vical, Inc. | Liponucleotide-containing liposomes |
NZ223910A (en) * | 1987-03-20 | 1991-02-26 | Bristol Myers Co | 2',3'-dideoxynucleosides, process for their production and intermediates therefor |
IL86007A0 (en) * | 1987-04-09 | 1988-09-30 | Wellcome Found | 6-substituted purine nucleosides,their preparation and pharmaceutical compositions containing them |
ZA886890B (en) * | 1987-10-09 | 1989-05-30 | Hoffmann La Roche | Novel dideoxycytidine derivatives |
US6599887B2 (en) | 1988-07-07 | 2003-07-29 | Chimerix, Inc. | Methods of treating viral infections using antiviral liponucleotides |
US6252060B1 (en) | 1988-07-07 | 2001-06-26 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
US5817638A (en) * | 1988-07-07 | 1998-10-06 | Nexstar Pharmaceuticals, Inc. | Antiviral liponucleosides: treatment of hepatitis B |
GB8823320D0 (en) * | 1988-10-05 | 1988-11-09 | Nycomed As | Chemical compounds |
EP0366385B1 (de) * | 1988-10-24 | 1993-06-09 | The Wellcome Foundation Limited | Guaninderivate mit antiviraler Wirkung und deren pharmazeutisch verträgliche Salze |
US5145960A (en) * | 1989-04-24 | 1992-09-08 | E. R. Squibb & Sons, Inc. | Pyrimidinyl tetrahydrofurans |
NZ232993A (en) * | 1989-04-24 | 1992-10-28 | Squibb & Sons Inc | Purinyl and pyrimidinyl tetrahydrofurans |
US5059690A (en) * | 1990-03-01 | 1991-10-22 | E. R. Squibb & Sons, Inc. | Purinyl tetrahydrofurans |
US5164520A (en) * | 1989-04-24 | 1992-11-17 | E. R. Squibb & Sons, Inc. | Intermediates for purinyl and pyrimidinyl tetrahydrofurans |
US5071983A (en) * | 1989-10-06 | 1991-12-10 | Burroughs Wellcome Co. | Therapeutic nucleosides |
CA2073063A1 (en) * | 1989-11-06 | 1991-05-07 | Jo Klaveness | Nucleoside derivatives |
US6703396B1 (en) | 1990-02-01 | 2004-03-09 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nuclesoside enantiomers |
US5276151A (en) * | 1990-02-01 | 1994-01-04 | Emory University | Method of synthesis of 1,3-dioxolane nucleosides |
US6069252A (en) * | 1990-02-01 | 2000-05-30 | Emory University | Method of resolution and antiviral activity of 1,3-oxathiolane nucleoside enantiomers |
US6642245B1 (en) | 1990-02-01 | 2003-11-04 | Emory University | Antiviral activity and resolution of 2-hydroxymethyl-5-(5-fluorocytosin-1-yl)-1,3-oxathiolane |
US5204466A (en) * | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
AU7558491A (en) * | 1990-04-04 | 1991-10-30 | Nycomed Imaging As | Nucleoside derivatives |
GB9007569D0 (en) * | 1990-04-04 | 1990-05-30 | Nycomed As | Carbo-nucleoside derivatives |
US5817667A (en) * | 1991-04-17 | 1998-10-06 | University Of Georgia Research Foudation | Compounds and methods for the treatment of cancer |
ES2067395B1 (es) * | 1993-03-10 | 1996-01-01 | Norsk Hydro As | Derivados de nucleosidos o analogos a nucleosidos. |
CA2171550C (en) * | 1993-09-10 | 2008-08-26 | Raymond F. Schinazi | Nucleosides with anti-hepatitis b virus activity |
US20020120130A1 (en) | 1993-09-10 | 2002-08-29 | Gilles Gosselin | 2' or 3' -deoxy and 2', 3' -dideoxy-beta-L-pentofuranonucleo-side compounds, method of preparation and application in therapy, especially as anti- viral agents |
US5587362A (en) * | 1994-01-28 | 1996-12-24 | Univ. Of Ga Research Foundation | L-nucleosides |
IL115156A (en) | 1994-09-06 | 2000-07-16 | Univ Georgia | Pharmaceutical compositions for the treatment of cancer comprising 1-(2-hydroxymethyl-1,3-dioxolan-4-yl) cytosines |
US5703058A (en) * | 1995-01-27 | 1997-12-30 | Emory University | Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent |
US6391859B1 (en) | 1995-01-27 | 2002-05-21 | Emory University | [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides |
US5808040A (en) * | 1995-01-30 | 1998-09-15 | Yale University | L-nucleosides incorporated into polymeric structure for stabilization of oligonucleotides |
ES2276404T3 (es) | 1995-06-07 | 2007-06-16 | Emory University | Nucleosidos con actividad antivirus de la hepatitis-b. |
US5753789A (en) * | 1996-07-26 | 1998-05-19 | Yale University | Oligonucleotides containing L-nucleosides |
US6436948B1 (en) | 2000-03-03 | 2002-08-20 | University Of Georgia Research Foundation Inc. | Method for the treatment of psoriasis and genital warts |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4177348A (en) * | 1977-12-13 | 1979-12-04 | United States Government | Carbocyclic analogs of cytosine nucleosides |
NZ216172A (en) * | 1985-05-15 | 1989-08-29 | Wellcome Found | Nucleosides and pharmaceutical compositions |
GB8712691D0 (en) * | 1987-05-29 | 1987-07-01 | Wellcome Found | Therapeutic nucleosides |
GB8823320D0 (en) * | 1988-10-05 | 1988-11-09 | Nycomed As | Chemical compounds |
-
1988
- 1988-03-23 NZ NZ223990A patent/NZ223990A/xx unknown
- 1988-03-23 JP JP63502580A patent/JPH02503312A/ja active Pending
- 1988-03-23 DE DE3850571T patent/DE3850571T2/de not_active Expired - Fee Related
- 1988-03-23 WO PCT/GB1988/000224 patent/WO1988007532A1/en active IP Right Grant
- 1988-03-23 AU AU14893/88A patent/AU613026B2/en not_active Ceased
- 1988-03-23 AT AT88902532T patent/ATE108183T1/de active
- 1988-03-23 EP EP88902532A patent/EP0342203B1/de not_active Expired - Lifetime
-
1989
- 1989-09-18 FI FI894397A patent/FI93217C/fi not_active IP Right Cessation
- 1989-09-19 OA OA59645A patent/OA09242A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1988007532A1 (en) | 1988-10-06 |
ATE108183T1 (de) | 1994-07-15 |
DE3850571T2 (de) | 1994-10-27 |
AU613026B2 (en) | 1991-07-25 |
FI93217B (fi) | 1994-11-30 |
AU1489388A (en) | 1988-11-02 |
NZ223990A (en) | 1990-08-28 |
FI894397A (fi) | 1989-09-18 |
EP0342203B1 (de) | 1994-07-06 |
FI93217C (fi) | 1995-03-10 |
FI894397A0 (fi) | 1989-09-18 |
EP0342203A1 (de) | 1989-11-23 |
DE3850571D1 (de) | 1994-08-11 |
JPH02503312A (ja) | 1990-10-11 |
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