NZ766350A - Sequencing data-based itd mutation ratio detecting apparatus and method - Google Patents
Sequencing data-based itd mutation ratio detecting apparatus and methodInfo
- Publication number
- NZ766350A NZ766350A NZ766350A NZ76635018A NZ766350A NZ 766350 A NZ766350 A NZ 766350A NZ 766350 A NZ766350 A NZ 766350A NZ 76635018 A NZ76635018 A NZ 76635018A NZ 766350 A NZ766350 A NZ 766350A
- Authority
- NZ
- New Zealand
- Prior art keywords
- itd
- detection
- samples
- detection results
- test samples
- Prior art date
Links
- 230000035772 mutation Effects 0.000 title claims abstract description 113
- 238000012163 sequencing technique Methods 0.000 title claims abstract description 64
- 238000000034 method Methods 0.000 title claims abstract description 51
- 238000001514 detection method Methods 0.000 claims abstract description 165
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- 238000011002 quantification Methods 0.000 claims abstract description 13
- 108091028043 Nucleic acid sequence Proteins 0.000 claims abstract description 11
- 238000007781 pre-processing Methods 0.000 claims abstract description 9
- 238000012360 testing method Methods 0.000 claims description 92
- 238000012549 training Methods 0.000 claims description 43
- 238000010801 machine learning Methods 0.000 claims description 34
- 239000002773 nucleotide Substances 0.000 claims description 13
- 125000003729 nucleotide group Chemical group 0.000 claims description 13
- 238000004590 computer program Methods 0.000 claims description 11
- 150000007523 nucleic acids Chemical group 0.000 claims description 10
- 238000012165 high-throughput sequencing Methods 0.000 claims description 9
- 238000007481 next generation sequencing Methods 0.000 description 15
- 208000031261 Acute myeloid leukaemia Diseases 0.000 description 12
- 239000000523 sample Substances 0.000 description 11
- 238000004422 calculation algorithm Methods 0.000 description 10
- 208000033776 Myeloid Acute Leukemia Diseases 0.000 description 8
- 238000010586 diagram Methods 0.000 description 7
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- 206010069754 Acquired gene mutation Diseases 0.000 description 1
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- 238000001712 DNA sequencing Methods 0.000 description 1
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- 206010064571 Gene mutation Diseases 0.000 description 1
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- 238000007480 sanger sequencing Methods 0.000 description 1
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- 241000894007 species Species 0.000 description 1
- 238000013517 stratification Methods 0.000 description 1
- 208000016595 therapy related acute myeloid leukemia and myelodysplastic syndrome Diseases 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/50—Mutagenesis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Hospice & Palliative Care (AREA)
- Theoretical Computer Science (AREA)
- Oncology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Microbiology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711395827 | 2017-12-21 | ||
| PCT/CN2018/122394 WO2019120254A1 (zh) | 2017-12-21 | 2018-12-20 | 一种基于测序数据检测itd突变比例的装置和方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ766350A true NZ766350A (en) | 2022-05-27 |
Family
ID=66994429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ766350A NZ766350A (en) | 2017-12-21 | 2018-12-20 | Sequencing data-based itd mutation ratio detecting apparatus and method |
Country Status (4)
| Country | Link |
|---|---|
| CN (1) | CN109943635A (zh) |
| AU (2) | AU2018391843B2 (zh) |
| NZ (1) | NZ766350A (zh) |
| WO (1) | WO2019120254A1 (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115424664B (zh) * | 2022-11-07 | 2023-03-10 | 北京雅康博生物科技有限公司 | 人为突变程度评估方法及装置 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040024532A1 (en) * | 2002-07-30 | 2004-02-05 | Robert Kincaid | Method of identifying trends, correlations, and similarities among diverse biological data sets and systems for facilitating identification |
| CN101560564A (zh) * | 2009-04-08 | 2009-10-21 | 北京华生恒业科技有限公司 | 一种检测装置及系统 |
| CN105331606A (zh) * | 2014-08-12 | 2016-02-17 | 焦少灼 | 应用于高通量测序的核酸分子定量方法 |
| CN105969856B (zh) * | 2016-05-13 | 2019-11-12 | 万康源(天津)基因科技有限公司 | 一种单细胞外显子测序肿瘤体细胞突变检测方法 |
| CN106845155B (zh) * | 2016-12-29 | 2021-11-16 | 安诺优达基因科技(北京)有限公司 | 一种用于检测内部串联重复的装置 |
| EP3378950A1 (en) * | 2017-03-21 | 2018-09-26 | Sequencing Multiplex SLK | Easy one-step amplification and labeling (eosal) |
-
2018
- 2018-03-27 CN CN201810255516.9A patent/CN109943635A/zh active Pending
- 2018-12-20 AU AU2018391843A patent/AU2018391843B2/en active Active
- 2018-12-20 WO PCT/CN2018/122394 patent/WO2019120254A1/zh active Application Filing
- 2018-12-20 NZ NZ766350A patent/NZ766350A/en unknown
-
2022
- 2022-08-18 AU AU2022218581A patent/AU2022218581B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN109943635A (zh) | 2019-06-28 |
| AU2022218581A1 (en) | 2022-09-15 |
| AU2022218581B2 (en) | 2023-09-28 |
| AU2018391843A1 (en) | 2020-08-06 |
| AU2018391843B2 (en) | 2022-07-07 |
| WO2019120254A1 (zh) | 2019-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 20 DEC 2023 BY PHILLIPS ORMONDE FITZPATRICK Effective date: 20221026 |
|
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 1 YEAR UNTIL 20 DEC 2024 BY ACUMASS Effective date: 20231121 |