NZ630621A - Methods and compositions for diagnosis and prognosis of renal injury and renal failure - Google Patents
Methods and compositions for diagnosis and prognosis of renal injury and renal failureInfo
- Publication number
- NZ630621A NZ630621A NZ630621A NZ63062110A NZ630621A NZ 630621 A NZ630621 A NZ 630621A NZ 630621 A NZ630621 A NZ 630621A NZ 63062110 A NZ63062110 A NZ 63062110A NZ 630621 A NZ630621 A NZ 630621A
- Authority
- NZ
- New Zealand
- Prior art keywords
- prognosis
- subject
- determining
- threshold
- event
- Prior art date
Links
- 206010061481 Renal injury Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000004393 prognosis Methods 0.000 title abstract 2
- 208000001647 Renal Insufficiency Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 201000006370 kidney failure Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 108010063045 Lactoferrin Proteins 0.000 abstract 3
- 238000003556 assay Methods 0.000 abstract 3
- 102100032241 Lactotransferrin Human genes 0.000 abstract 2
- 210000001124 body fluid Anatomy 0.000 abstract 2
- 239000010839 body fluid Substances 0.000 abstract 2
- 208000037806 kidney injury Diseases 0.000 abstract 2
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 abstract 2
- 229940078795 lactoferrin Drugs 0.000 abstract 2
- 235000021242 lactoferrin Nutrition 0.000 abstract 2
- 102000012174 Lactotransferrin Human genes 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 238000013517 stratification Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/50—Determining the risk of developing a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15039309P | 2009-02-06 | 2009-02-06 | |
| US15037209P | 2009-02-06 | 2009-02-06 | |
| US15037409P | 2009-02-06 | 2009-02-06 | |
| US16239609P | 2009-03-23 | 2009-03-23 | |
| US16240209P | 2009-03-23 | 2009-03-23 | |
| US16633309P | 2009-04-03 | 2009-04-03 | |
| NZ609666A NZ609666A (en) | 2009-02-06 | 2010-02-05 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ630621A true NZ630621A (en) | 2016-03-31 |
Family
ID=42542388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ630621A NZ630621A (en) | 2009-02-06 | 2010-02-05 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20160123996A1 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2393937A4 (cg-RX-API-DMAC10.html) |
| JP (3) | JP2012517592A (cg-RX-API-DMAC10.html) |
| CN (3) | CN102369293B (cg-RX-API-DMAC10.html) |
| AU (1) | AU2010210535B2 (cg-RX-API-DMAC10.html) |
| BR (1) | BRPI1007917A2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2751424A1 (cg-RX-API-DMAC10.html) |
| HK (1) | HK1200218A1 (cg-RX-API-DMAC10.html) |
| MX (1) | MX2011008323A (cg-RX-API-DMAC10.html) |
| NZ (1) | NZ630621A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2010091231A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2735590A1 (en) | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2449385A1 (de) * | 2009-07-02 | 2012-05-09 | Mosaiques Diagnostics And Therapeutics AG | Verfahren und marker zur diagnose eines akuten nierenversagens |
| MX348303B (es) * | 2010-09-24 | 2017-06-06 | Astute Medical Inc | Métodos y composiciones para la evaluación de lesión renal utilizando ácido hialurónico. |
| US20150241415A1 (en) * | 2012-08-11 | 2015-08-27 | Astute Medical, Inc. | Evaluating renal injury using hyaluronic acid |
| US20160011194A1 (en) * | 2013-01-29 | 2016-01-14 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN110007084B (zh) * | 2013-12-03 | 2022-11-18 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断和预后的方法和组合物 |
| CL2015003047A1 (es) * | 2015-10-15 | 2016-06-17 | Univ Chile | Método ex vivo para detectar precozmente injuria renal aguda en pacientes críticos, que comprende la mediciom en una muestra de tres proteinas como biomarcadores, factor de crecimiento fibroblástico 23, klotho y eritropoyetina |
| CN105466984B (zh) * | 2016-01-14 | 2018-12-28 | 郑以山 | 用于肾脏非显性损伤的预警装置及其使用方法 |
| JP6414869B2 (ja) * | 2016-01-29 | 2018-10-31 | 株式会社国際電気通信基礎技術研究所 | 腎機能の評価装置、腎疾患の合併症の発症の予測装置、およびリン摂取量推定装置 |
| CN106845140A (zh) * | 2017-03-01 | 2017-06-13 | 重庆工商大学 | 一种基于尿比重和尿量监测的肾衰竭预警方法及系统 |
| RU2019144031A (ru) * | 2017-05-30 | 2021-06-30 | Сфинготек Гмбх | Способ диагностики или мониторинга функции почек или диагностики дисфункции почек |
| CN109897108B (zh) * | 2019-03-11 | 2021-04-02 | 上海恒赛生物科技有限公司 | 抗人内皮蛋白c受体的羊驼单域抗体及应用 |
| EP3881862A1 (de) * | 2020-03-18 | 2021-09-22 | Pharis Biotec GmbH | Polypeptid zur therapie von glomerulären nierenerkrankungen und analyse des verlaufes und prognose der abhängigen syndrome |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3569577B2 (ja) * | 1995-09-04 | 2004-09-22 | 株式会社いかがく | 腎・尿路系疾患の鑑別診断用キット |
| US6498142B1 (en) * | 1996-05-06 | 2002-12-24 | Curis, Inc. | Morphogen treatment for chronic renal failure |
| US6228360B1 (en) * | 1998-08-19 | 2001-05-08 | Ajinomoto Co., Inc. | Antithrombotic agent and humanized anti-von Willebrand factor monoclonal antibody |
| JP2003030100A (ja) * | 2001-07-12 | 2003-01-31 | Fuji Xerox Co Ltd | インターネット情報提供システムおよびインターネット情報提供方法 |
| ES2268961B1 (es) * | 2005-03-17 | 2008-03-16 | Proyecto De Biomedicina Cima, S.L. | Nueva proteina epcr soluble de origen no proteolitico y su uso. |
| WO2007013919A2 (en) * | 2005-07-21 | 2007-02-01 | The Johns Hopkins University | Methods of detecting and treating acute kidney injury |
| TW200726845A (en) * | 2006-01-02 | 2007-07-16 | Nat Defense Medical Ct | Biomarker molecular of renal illness and detecting method for the same |
| US7662578B2 (en) * | 2006-04-21 | 2010-02-16 | Children's Hospital Medical Center | Method and kit for the early detection of impaired renal status |
| US20080038269A1 (en) * | 2006-05-25 | 2008-02-14 | Mount Sinai Hospital | Methods for detecting and treating kidney disease |
| GB0617429D0 (en) * | 2006-09-05 | 2006-10-18 | Electrophoretics Ltd | Markers of renal transplant rejection and renal damage |
| US7842472B2 (en) * | 2006-11-14 | 2010-11-30 | Alere International | Methods and compositions for monitoring and risk prediction in cardiorenal syndrome |
| WO2008154238A1 (en) * | 2007-06-06 | 2008-12-18 | Siemens Healthcare Diagnostics Inc. | Predictive diagnostics for kidney disease |
-
2010
- 2010-02-05 CN CN201080013522.5A patent/CN102369293B/zh not_active Expired - Fee Related
- 2010-02-05 EP EP10739150A patent/EP2393937A4/en not_active Withdrawn
- 2010-02-05 CA CA2751424A patent/CA2751424A1/en not_active Abandoned
- 2010-02-05 WO PCT/US2010/023292 patent/WO2010091231A1/en not_active Ceased
- 2010-02-05 CN CN201410171245.0A patent/CN104111336B/zh not_active Expired - Fee Related
- 2010-02-05 NZ NZ630621A patent/NZ630621A/en not_active IP Right Cessation
- 2010-02-05 JP JP2011549275A patent/JP2012517592A/ja active Pending
- 2010-02-05 CN CN201611051979.0A patent/CN106546752A/zh active Pending
- 2010-02-05 MX MX2011008323A patent/MX2011008323A/es active IP Right Grant
- 2010-02-05 AU AU2010210535A patent/AU2010210535B2/en not_active Ceased
- 2010-02-05 BR BRPI1007917A patent/BRPI1007917A2/pt not_active IP Right Cessation
-
2015
- 2015-01-20 HK HK15100634.5A patent/HK1200218A1/xx unknown
- 2015-01-27 JP JP2015013153A patent/JP2015096870A/ja active Pending
-
2016
- 2016-01-04 US US14/987,569 patent/US20160123996A1/en not_active Abandoned
- 2016-07-04 JP JP2016132688A patent/JP2016194526A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2751424A1 (en) | 2010-08-12 |
| CN102369293B (zh) | 2014-05-28 |
| US20160123996A1 (en) | 2016-05-05 |
| CN104111336A (zh) | 2014-10-22 |
| JP2015096870A (ja) | 2015-05-21 |
| CN104111336B (zh) | 2017-01-18 |
| CN102369293A (zh) | 2012-03-07 |
| EP2393937A1 (en) | 2011-12-14 |
| JP2016194526A (ja) | 2016-11-17 |
| MX2011008323A (es) | 2011-09-21 |
| WO2010091231A1 (en) | 2010-08-12 |
| AU2010210535B2 (en) | 2015-12-10 |
| BRPI1007917A2 (pt) | 2019-09-24 |
| HK1200218A1 (en) | 2015-07-31 |
| JP2012517592A (ja) | 2012-08-02 |
| HK1162617A1 (en) | 2012-08-31 |
| CN106546752A (zh) | 2017-03-29 |
| EP2393937A4 (en) | 2012-08-08 |
| AU2010210535A1 (en) | 2011-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 05 FEB 2017 BY FB RICE Effective date: 20160704 |
|
| LAPS | Patent lapsed |