NZ594110A - Method of double crossover homologous recombination in clostridia - Google Patents

Method of double crossover homologous recombination in clostridia

Info

Publication number
NZ594110A
NZ594110A NZ594110A NZ59411010A NZ594110A NZ 594110 A NZ594110 A NZ 594110A NZ 594110 A NZ594110 A NZ 594110A NZ 59411010 A NZ59411010 A NZ 59411010A NZ 594110 A NZ594110 A NZ 594110A
Authority
NZ
New Zealand
Prior art keywords
homologous recombination
clostridia
recombination event
host cell
double crossover
Prior art date
Application number
NZ594110A
Other languages
English (en)
Inventor
Stephen Thomas Cartman
Nigel Peter Minton
Original Assignee
Univ Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nottingham filed Critical Univ Nottingham
Publication of NZ594110A publication Critical patent/NZ594110A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90Stable introduction of foreign DNA into chromosome
    • C12N15/902Stable introduction of foreign DNA into chromosome using homologous recombination

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
NZ594110A 2009-01-22 2010-01-21 Method of double crossover homologous recombination in clostridia NZ594110A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0901001.8A GB0901001D0 (en) 2009-01-22 2009-01-22 Methods
PCT/GB2010/050084 WO2010084349A1 (en) 2009-01-22 2010-01-21 Method of double crossover homologous recombination in clostridia

Publications (1)

Publication Number Publication Date
NZ594110A true NZ594110A (en) 2013-03-28

Family

ID=40446145

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ594110A NZ594110A (en) 2009-01-22 2010-01-21 Method of double crossover homologous recombination in clostridia

Country Status (6)

Country Link
US (1) US20120100616A1 (xx)
EP (1) EP2389440A1 (xx)
CN (1) CN102361986A (xx)
GB (1) GB0901001D0 (xx)
NZ (1) NZ594110A (xx)
WO (1) WO2010084349A1 (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9267106B2 (en) 2011-02-14 2016-02-23 Eastman Renewable Materials, Llc Method for incorporation of recombinant DNA
US8692024B2 (en) 2011-02-14 2014-04-08 Eastman Renewable Materials, Llc Method of producing n-butyraldehyde
BR112013027229B1 (pt) 2011-04-22 2020-10-27 Wyeth Llc polipeptídeo imunogênico isolado e seu uso, composição imunogênica e seu uso, célula recombinante ou progênie da mesma, e método de produção de uma toxina de clostridium difficile mutante
WO2013133882A2 (en) * 2011-12-16 2013-09-12 University Of Delaware Recombinant clostridium organism and method for isolation of double-crossover allelic exchange mutants
BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
US9315830B2 (en) 2014-01-28 2016-04-19 Lanzatech New Zealand Limited Method of producing a recombinant microorganism
WO2016153355A2 (en) 2015-03-26 2016-09-29 Microbiome Limited Novel isolation and amplification process control
CN108866050B (zh) * 2017-05-11 2022-12-27 杭州菁因康生物科技有限公司 一种高效的基因工程载体
GB202019767D0 (en) 2020-12-15 2021-01-27 Chain Biotechnology Ltd Compostitions and methods
GB202209115D0 (en) 2022-06-21 2022-08-10 Chain Biotechnology Ltd Compositions and methods

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006130925A1 (en) * 2005-06-10 2006-12-14 Monash University Genetic manipulation of clostridium difficile
BRPI0622182B1 (pt) * 2006-10-03 2018-07-31 Metabolic Explorer Processo para a substituição de uma sequência de DNA alvo através de recombinação homóloga em Clostridia, cepa recombinante de Clostridium e vetor para a substituição de uma sequência de DNA alvo por recombinação homóloga em Clostridia
GB0802842D0 (en) * 2008-02-15 2008-03-26 Univ Nottingham Synthetic operon construction in clostridia

Also Published As

Publication number Publication date
WO2010084349A1 (en) 2010-07-29
EP2389440A1 (en) 2011-11-30
CN102361986A (zh) 2012-02-22
US20120100616A1 (en) 2012-04-26
GB0901001D0 (en) 2009-03-04

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