NZ593585A - Crystalline forms of vorinostat (suberoylanilide hydroxamic acid) - Google Patents

Crystalline forms of vorinostat (suberoylanilide hydroxamic acid)

Info

Publication number
NZ593585A
NZ593585A NZ593585A NZ59358509A NZ593585A NZ 593585 A NZ593585 A NZ 593585A NZ 593585 A NZ593585 A NZ 593585A NZ 59358509 A NZ59358509 A NZ 59358509A NZ 593585 A NZ593585 A NZ 593585A
Authority
NZ
New Zealand
Prior art keywords
vorinostat
hydroxamic acid
suberoylanilide hydroxamic
crystalline forms
crystalline
Prior art date
Application number
NZ593585A
Other languages
English (en)
Inventor
Vinayak Gore
Madhukar Patil
Rahul Bhalerao
Hemant Mande
Original Assignee
Generics Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Generics Uk Ltd filed Critical Generics Uk Ltd
Publication of NZ593585A publication Critical patent/NZ593585A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ593585A 2008-11-26 2009-11-25 Crystalline forms of vorinostat (suberoylanilide hydroxamic acid) NZ593585A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2057KO2008 2008-11-26
PCT/GB2009/051596 WO2010061219A2 (en) 2008-11-26 2009-11-25 Polymorphs

Publications (1)

Publication Number Publication Date
NZ593585A true NZ593585A (en) 2012-12-21

Family

ID=42226168

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ593585A NZ593585A (en) 2008-11-26 2009-11-25 Crystalline forms of vorinostat (suberoylanilide hydroxamic acid)

Country Status (8)

Country Link
US (1) US8754129B2 (enExample)
EP (1) EP2362869A2 (enExample)
JP (1) JP2012509929A (enExample)
CN (1) CN102282126A (enExample)
AU (1) AU2009321384A1 (enExample)
CA (1) CA2744448A1 (enExample)
NZ (1) NZ593585A (enExample)
WO (1) WO2010061219A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2349985A2 (en) 2008-10-15 2011-08-03 Generics [UK] Limited Process for the preparation of vorinostat
CN110283102B (zh) * 2019-05-31 2022-09-27 宿州亿帆药业有限公司 一种伏林司他ⅰ晶型的制备方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5369108A (en) 1991-10-04 1994-11-29 Sloan-Kettering Institute For Cancer Research Potent inducers of terminal differentiation and methods of use thereof
GB9504084D0 (en) 1995-03-01 1995-04-19 British Biotech Pharm Synthesis of carboxylic and hydroxamic acid derivatives
IT1283637B1 (it) 1996-05-14 1998-04-23 Italfarmaco Spa Composti ad attivita' antinfiammatoria ed immunosoppressiva
US6497820B1 (en) 1998-02-03 2002-12-24 Arqule, Inc. Rapid method for separation of small molecules using reverse phase high performance liquid chromatography
CA2391952C (en) 1999-11-23 2012-01-31 Methylgene Inc. Inhibitors of histone deacetylase
US7456219B2 (en) 2002-03-04 2008-11-25 Merck Hdac Research, Llc Polymorphs of suberoylanilide hydroxamic acid
NZ550185A (en) 2002-03-04 2008-10-31 Merck Hdac Res Llc Methods of inducing terminal differentiation Methods of inducing terminal differentiation
EP1663194B1 (en) 2003-08-26 2010-03-31 Merck HDAC Research, LLC Use of SAHA for treating mesothelioma
EP1541549A1 (en) 2003-12-12 2005-06-15 Exonhit Therapeutics S.A. Tricyclic hydroxamate and benzaminde derivatives, compositions and methods
UA93355C2 (ru) * 2005-05-20 2011-02-10 Mepk Шарп Энд Доме Корп. Композиция субероиланилид-гидроксаминовой кислоты и способы ee получения
TWI415603B (zh) 2005-05-20 2013-11-21 Merck Sharp & Dohme １，８－辛二醯基苯胺羥胺酸（ｓｕｂｅｒｏｙｌａｎｉｌｉｄｅ ｈｙｄｒｏｘａｍｉｃ ａｃｉｄ）之調配物及其製配方法
CA2663569A1 (en) * 2006-09-28 2008-04-03 Merck & Co., Inc. Pharmaceutical compositions of hdac inhibitors and chelatable metal compounds, and metal-hdac inhibitor chelate complexes
CA2663614A1 (en) 2006-09-28 2008-04-10 Merck And Co., Inc. Amine base salts of saha and polymorphs thereof
AU2008337304A1 (en) 2007-12-14 2009-06-25 Generics [Uk] Limited HPLC method for analysing clopidogrel
JP2011511053A (ja) 2008-02-07 2011-04-07 ジェネリクス・（ユーケー）・リミテッド ボリノスタットの新規な製造方法
US20090223286A1 (en) 2008-02-13 2009-09-10 Vandana Singh Analytical method for determination of related substances of imipenem and cilastatin
CZ2008167A3 (cs) 2008-03-14 2010-02-24 Zentiva, A. S. Specifické necistoty montelukastu
EP2349985A2 (en) 2008-10-15 2011-08-03 Generics [UK] Limited Process for the preparation of vorinostat
CA2744458A1 (en) 2008-11-26 2010-06-03 Generics [Uk] Limited Novel processes and pure polymorphs
WO2011061545A1 (en) 2009-11-23 2011-05-26 Generics [Uk] Limited Hplc method for analyzing vorinostat

Also Published As

Publication number Publication date
JP2012509929A (ja) 2012-04-26
US8754129B2 (en) 2014-06-17
US20110263713A1 (en) 2011-10-27
CN102282126A (zh) 2011-12-14
WO2010061219A2 (en) 2010-06-03
EP2362869A2 (en) 2011-09-07
CA2744448A1 (en) 2010-06-03
WO2010061219A3 (en) 2010-08-12
AU2009321384A1 (en) 2011-06-23

Similar Documents

Publication Publication Date Title
WO2008083967A3 (en) Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid
WO2008047229A3 (en) Biaryl ether urea compounds
WO2010042168A3 (en) Methods for making ethanolamine(s) and ethyleneamine(s) from ethylene oxide and ammonia, and related methods
WO2008009407A3 (en) Sulphonylaminocarbonyl derivatives of bile acid amides for use as immunomodulators
WO2010085104A3 (ko) 전극 활물질인 음이온 부족형 리튬 전이금속 인산화합물, 그 제조방법, 및 그를 이용한 전기화학 소자
MY150057A (en) Process for the production of urea from ammonia and carbon dioxide
MX2011012334A (es) Composicion y metodo para promover el crecimiento de raices de plantas.
WO2008114506A1 (ja) ４－アミノメチル安息香酸の製造方法
WO2011154140A3 (en) Process for the preparation of n- [2 - (7 -methoxy - 1 - naphthyl) - ethyl] acetamide and new crystalline form
WO2011144983A3 (en) An improved process for the preparation of lacosamide
WO2011112596A3 (en) Method of making a cyclic guanidine from a guanidinium salt and a weak acid and coating compositions containing same
JO2928B1 (en) Method of synthesis of ferroquine by convergent reductive amination
WO2012061460A3 (en) Method for producing ammonium sulfate nitrate
WO2010089778A3 (en) Process for the synthesis of cleistanthin
WO2011154333A3 (de) Verfahren zur herstellung kristalliner 3,6,9-triaza-3,6,9-tris(carboxymethyl)-4-(4-ethoxybenzyl)-undecandisäure und die verwendung zur herstellung von primovist®
WO2012148148A3 (en) Novel zinc azide complex and a process for preparing tetrazole derivatives using the same
WO2012148246A3 (en) A preparation method of sitagliptin
WO2009122429A3 (en) Crystalline oxybutynin and process for preparing the same
WO2011087211A3 (ko) 4-아미노메틸벤조산의 제조방법
WO2010107993A3 (en) Process for preparing (r)-7v-benzyl-2- (benyloxycarbonylamino)-s-methoxypropionamide
ZA200800138B (en) Process for the preparation of crystalline perindopril
PL2289869T3 (pl) Sposób wytwarzania chelatów Fe(III) kwasu N,N` -di(2- hydroksybenzylo)etylenodiamino-N,N`-dioctowego i jego pochodnych
WO2013117869A3 (fr) Procédé de synthèse enzymatique de l'acide (7s)-3,4-dimethoxybicyclo [4.2.0]|octa-1,3,5-triene-7-carboxylique ou de ses esters, et application a la synthèse|de l'ivabradine et de ses sels
WO2010059503A3 (en) PROCESS FOR MAKING (R) -3-(2,3-DIHYDROXYPROPYL)-6-FLUORO-5-(2-FLOURO-4-IODOPHENYLAMINO)-8-METHYLPYRIDO[2,3-d]PYRIMIDINE-4,7(3H,8H)-DIONE AND INTERMEDIATES THEREOF
WO2009063804A1 (ja) Ｎ－カルバモイル－ｔｅｒｔ－ロイシンの製造法

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 25 NOV 2016 BY DENNEMEYER SA

Effective date: 20131115

LAPS Patent lapsed