NZ592882A - Mucoadhesive film comprising testosterone and cellulose derivatives - Google Patents
Mucoadhesive film comprising testosterone and cellulose derivativesInfo
- Publication number
- NZ592882A NZ592882A NZ592882A NZ59288206A NZ592882A NZ 592882 A NZ592882 A NZ 592882A NZ 592882 A NZ592882 A NZ 592882A NZ 59288206 A NZ59288206 A NZ 59288206A NZ 592882 A NZ592882 A NZ 592882A
- Authority
- NZ
- New Zealand
- Prior art keywords
- androgen
- mucoadhesive film
- testosterone
- carrier material
- film
- Prior art date
Links
- 230000003232 mucoadhesive effect Effects 0.000 title abstract 5
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical class O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 title abstract 4
- 229960003604 testosterone Drugs 0.000 title abstract 2
- 229920002678 cellulose Chemical class 0.000 title 1
- 239000001913 cellulose Chemical class 0.000 title 1
- 239000003098 androgen Substances 0.000 abstract 4
- 239000012876 carrier material Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229960004719 nandrolone Drugs 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 239000001856 Ethyl cellulose Substances 0.000 abstract 1
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 abstract 1
- 238000005266 casting Methods 0.000 abstract 1
- 238000001035 drying Methods 0.000 abstract 1
- 229920001249 ethyl cellulose Polymers 0.000 abstract 1
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 abstract 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 229920000609 methyl cellulose Polymers 0.000 abstract 1
- 239000001923 methylcellulose Substances 0.000 abstract 1
- 235000010981 methylcellulose Nutrition 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/40—Mineralocorticosteroids, e.g. aldosterone; Drugs increasing or potentiating the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005015128A DE102005015128B4 (de) | 2005-03-31 | 2005-03-31 | Wafer enthaltend Steroidhormone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ592882A true NZ592882A (en) | 2012-12-21 |
Family
ID=36998911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ592882A NZ592882A (en) | 2005-03-31 | 2006-03-15 | Mucoadhesive film comprising testosterone and cellulose derivatives |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US9763960B2 (https=) |
| EP (1) | EP1863444B1 (https=) |
| JP (2) | JP5843416B2 (https=) |
| KR (2) | KR20140063740A (https=) |
| CN (2) | CN101132766A (https=) |
| AR (1) | AR054245A1 (https=) |
| AU (1) | AU2006228820B2 (https=) |
| BR (1) | BRPI0609601A2 (https=) |
| CA (1) | CA2598892C (https=) |
| CR (1) | CR9468A (https=) |
| DE (1) | DE102005015128B4 (https=) |
| DO (1) | DOP2006000070A (https=) |
| EA (1) | EA014183B1 (https=) |
| GT (1) | GT200600126A (https=) |
| IL (1) | IL186081A0 (https=) |
| MX (1) | MX2007012081A (https=) |
| NO (1) | NO20075404L (https=) |
| NZ (1) | NZ592882A (https=) |
| PE (1) | PE20061194A1 (https=) |
| SG (1) | SG179459A1 (https=) |
| SV (1) | SV2008002466A (https=) |
| TW (1) | TWI393576B (https=) |
| UA (1) | UA92011C2 (https=) |
| UY (1) | UY29441A1 (https=) |
| WO (1) | WO2006102990A2 (https=) |
| ZA (1) | ZA200706116B (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2604943C (en) | 2005-04-15 | 2013-09-17 | Clarus Therapeutics, Inc. | Pharmaceutical delivery systems for hydrophobic drugs and compositions comprising same |
| US8492369B2 (en) | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
| DE102006027796A1 (de) * | 2006-06-16 | 2007-12-20 | Lts Lohmann Therapie-Systeme Ag | Estrogen-Gestagen-Kombinationen |
| NZ586666A (en) * | 2008-02-13 | 2012-04-27 | Bayer Schering Pharma Ag | Estradiol-containing drug delivery system |
| EA018330B1 (ru) * | 2008-02-13 | 2013-07-30 | Байер Интеллекчуал Проперти Гмбх | Система доставки лекарственного средства со стабилизирующим эффектом |
| TW201008569A (en) * | 2008-08-08 | 2010-03-01 | Bayer Schering Pharma Ag | Progestin-containing drug delivery system |
| WO2010057594A1 (en) * | 2008-11-21 | 2010-05-27 | Bayer Schering Pharma Aktiengesellschaft | Drug delivery system |
| US12186426B2 (en) | 2009-10-30 | 2025-01-07 | Ix Biopharma Ltd. | Solid dosage form |
| DK3254676T3 (en) | 2009-10-30 | 2019-03-11 | Ix Biopharma Ltd | QUICK-SOLVING SOLID DOSAGE FORM |
| US10806703B2 (en) * | 2012-01-20 | 2020-10-20 | Lts Lohmann Therapie-System Ag | Transmucosal administration system for a pharmaceutical drug |
| EP2874824B1 (en) | 2012-07-23 | 2025-04-30 | Crayola, LLC | Dissolvable films and methods of using the same |
| DE102017112527B4 (de) * | 2017-06-07 | 2019-01-03 | Lts Lohmann Therapie-Systeme Ag | Schnell zerfallende Schaumwafer mit hohem Flächengewicht |
| AU2019215163A1 (en) * | 2018-02-02 | 2020-08-20 | Acerus Biopharma Inc. | Methods of testosterone therapy |
| US11564933B2 (en) | 2019-04-12 | 2023-01-31 | Tolmar, Inc. | Methods of treating testosterone deficiency |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB981372A (en) * | 1960-05-04 | 1965-01-27 | Pfizer Ltd | Pharmaceutical formulations for oral administration to animals |
| US4136162A (en) | 1974-07-05 | 1979-01-23 | Schering Aktiengesellschaft | Medicament carriers in the form of film having active substance incorporated therein |
| US4764378A (en) * | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
| ES2105262T3 (es) * | 1992-05-18 | 1997-10-16 | Minnesota Mining & Mfg | Dispositivo de suministro de farmaco a traves de las mucosas. |
| DE19646392A1 (de) * | 1996-11-11 | 1998-05-14 | Lohmann Therapie Syst Lts | Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht |
| DE19847252B4 (de) * | 1998-10-02 | 2004-02-12 | Jenapharm Gmbh & Co. Kg | Bukkal applizierbare bioadhäsive Systeme mit zeitlich gesteuerter Wirkstofffreisetzung enthaltend Testosteronester und fakultativ zusätzlich Testosteron |
| US6552024B1 (en) * | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
| US6264981B1 (en) * | 1999-10-27 | 2001-07-24 | Anesta Corporation | Oral transmucosal drug dosage using solid solution |
| US20030092658A1 (en) * | 2001-02-02 | 2003-05-15 | Meyers Rachel E. | Novel human enzyme family members and uses thereof |
| WO2002003965A1 (en) * | 2000-07-06 | 2002-01-17 | Delsys Pharmaceutical Corporation | Method for formulating healthcare products with enhanced stability |
| GB0100760D0 (en) * | 2001-01-11 | 2001-02-21 | Biocompatibles Ltd | Drug delivery from stents |
| US6585997B2 (en) * | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
| FR2832311B1 (fr) * | 2001-11-21 | 2004-04-16 | Besins Int Belgique | Poudre filmogene, compositions la comprenant, leurs procedes de preparation et leurs utilisations |
| JO2492B1 (en) * | 2003-04-28 | 2009-10-05 | شيرينج ايه جي | A pharmaceutical formula in the form of aqueous gel for the skin use of its active ingredients |
| JP2007500729A (ja) * | 2003-07-31 | 2007-01-18 | アイバックス コーポレイション | 雄性及び雌性の性機能障害の治療方法 |
| DK1670433T3 (da) * | 2003-10-10 | 2012-03-12 | Ferring Bv | Transdermal farmaceutisk formulering til mindskelse af hudrester |
-
2005
- 2005-03-31 DE DE102005015128A patent/DE102005015128B4/de not_active Expired - Fee Related
-
2006
- 2006-03-13 TW TW095108474A patent/TWI393576B/zh not_active IP Right Cessation
- 2006-03-15 SG SG2012016937A patent/SG179459A1/en unknown
- 2006-03-15 NZ NZ592882A patent/NZ592882A/xx not_active IP Right Cessation
- 2006-03-15 BR BRPI0609601-8A patent/BRPI0609601A2/pt not_active Application Discontinuation
- 2006-03-15 CA CA2598892A patent/CA2598892C/en not_active Expired - Lifetime
- 2006-03-15 WO PCT/EP2006/002358 patent/WO2006102990A2/de not_active Ceased
- 2006-03-15 AU AU2006228820A patent/AU2006228820B2/en not_active Ceased
- 2006-03-15 EP EP06723435.1A patent/EP1863444B1/de not_active Expired - Lifetime
- 2006-03-15 EA EA200702102A patent/EA014183B1/ru not_active IP Right Cessation
- 2006-03-15 JP JP2008503397A patent/JP5843416B2/ja not_active Expired - Fee Related
- 2006-03-15 UA UAA200712054A patent/UA92011C2/ru unknown
- 2006-03-15 KR KR1020147008056A patent/KR20140063740A/ko not_active Ceased
- 2006-03-15 KR KR1020077022368A patent/KR101428625B1/ko not_active Expired - Fee Related
- 2006-03-15 CN CNA2006800071551A patent/CN101132766A/zh active Pending
- 2006-03-15 MX MX2007012081A patent/MX2007012081A/es active IP Right Grant
- 2006-03-15 CN CN201510393577.8A patent/CN104983669B/zh not_active Expired - Fee Related
- 2006-03-27 DO DO2006000070A patent/DOP2006000070A/es unknown
- 2006-03-27 SV SV2006002466A patent/SV2008002466A/es not_active Application Discontinuation
- 2006-03-27 GT GT200600126A patent/GT200600126A/es unknown
- 2006-03-27 UY UY29441A patent/UY29441A1/es not_active Application Discontinuation
- 2006-03-27 PE PE2006000341A patent/PE20061194A1/es not_active Application Discontinuation
- 2006-03-28 US US11/391,646 patent/US9763960B2/en not_active Expired - Fee Related
- 2006-03-31 AR AR20060101273A patent/AR054245A1/es not_active Application Discontinuation
-
2007
- 2007-07-24 ZA ZA200706116A patent/ZA200706116B/xx unknown
- 2007-09-19 IL IL186081A patent/IL186081A0/en unknown
- 2007-10-23 CR CR9468A patent/CR9468A/es unknown
- 2007-10-24 NO NO20075404A patent/NO20075404L/no not_active Application Discontinuation
-
2013
- 2013-04-18 JP JP2013087238A patent/JP2013155190A/ja active Pending
-
2017
- 2017-08-23 US US15/684,245 patent/US20170348321A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
Free format text: PATENT RENEWED FOR 6 YEARS UNTIL 15 MAR 2016 BY DENNEMEYER + CO Effective date: 20130408 |
|
| ASS | Change of ownership |
Owner name: LTS LOHMANN THERAPIE-SYSTEME AG, DE Effective date: 20130815 Owner name: BAYER INTELLECTUAL PROPERTY GMBH, DE Effective date: 20130815 |
|
| LAPS | Patent lapsed |