NZ571324A - Method of preventing and treating hepatic disease using A2B adenoise receptor antagonists - Google Patents

Info

Publication number

NZ571324A

NZ571324A NZ571324A NZ57132407A NZ571324A NZ 571324 A NZ571324 A NZ 571324A NZ 571324 A NZ571324 A NZ 571324A NZ 57132407 A NZ57132407 A NZ 57132407A NZ 571324 A NZ571324 A NZ 571324A

Authority

NZ

New Zealand

Prior art keywords

formula

methyl

amino

compound

dione

Prior art date

2006-03-17

Links

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• Global Dossier
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• 238000000034 method Methods 0.000 title description 62
• 229940044551 receptor antagonist Drugs 0.000 title description 3
• 239000002464 receptor antagonist Substances 0.000 title description 3
• 239000000203 mixture Substances 0.000 claims abstract description 61
• 101150078577 Adora2b gene Proteins 0.000 claims abstract description 47
• 229940121359 adenosine receptor antagonist Drugs 0.000 claims abstract description 23
• 239000000296 purinergic P1 receptor antagonist Substances 0.000 claims abstract description 23
• 241000124008 Mammalia Species 0.000 claims abstract description 12
• 238000004519 manufacturing process Methods 0.000 claims abstract description 5
• 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 42
• 230000000694 effects Effects 0.000 claims description 30
• 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 28
• 238000011282 treatment Methods 0.000 claims description 27
• 239000003814 drug Substances 0.000 claims description 20
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