NZ569690A - Vitamin D analog - RAK, methods and uses thereof - Google Patents
Vitamin D analog - RAK, methods and uses thereofInfo
- Publication number
- NZ569690A NZ569690A NZ569690A NZ56969007A NZ569690A NZ 569690 A NZ569690 A NZ 569690A NZ 569690 A NZ569690 A NZ 569690A NZ 56969007 A NZ56969007 A NZ 56969007A NZ 569690 A NZ569690 A NZ 569690A
- Authority
- NZ
- New Zealand
- Prior art keywords
- compound
- vitamin
- lack
- pharmaceutical composition
- adequate
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Immunology (AREA)
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- Gerontology & Geriatric Medicine (AREA)
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- Birds (AREA)
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- Biomedical Technology (AREA)
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- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74321906P | 2006-02-02 | 2006-02-02 | |
| PCT/US2007/061404 WO2007092721A2 (en) | 2006-02-02 | 2007-01-31 | Vitamin d analog: rak, methods and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ569690A true NZ569690A (en) | 2011-10-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ569690A NZ569690A (en) | 2006-02-02 | 2007-01-31 | Vitamin D analog - RAK, methods and uses thereof |
Country Status (10)
| Country | Link |
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| US (1) | US7803789B2 (https=) |
| EP (1) | EP1984329B1 (https=) |
| JP (1) | JP5113766B2 (https=) |
| AT (1) | ATE451352T1 (https=) |
| AU (1) | AU2007212185B2 (https=) |
| CA (1) | CA2637302C (https=) |
| DE (1) | DE602007003691D1 (https=) |
| ES (1) | ES2339402T3 (https=) |
| NZ (1) | NZ569690A (https=) |
| WO (1) | WO2007092721A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2009533483A (ja) * | 2006-04-06 | 2009-09-17 | ウイスコンシン アラムニ リサーチ ファンデーション | ２−メチレン−１α，２５−ジヒドロキシ−１８，１９，２１−トリノルビタミンＤ３およびその使用 |
| US7648973B2 (en) * | 2006-04-06 | 2010-01-19 | Wisconsin Alumni Research Foundation | 2-methylene-1α,25-dihydroxy-19,21-dinorvitamin D3 analogs and uses thereof |
| CA2646909A1 (en) * | 2006-04-06 | 2008-03-27 | Hector F. Deluca | 2-methylene-1alpha-hydroxy-19,21-dinorvitamin d3 analogs and uses thereof |
| US8193169B2 (en) * | 2006-04-06 | 2012-06-05 | Wisconsin Alumni Research Foundation | (20R)-2α-methyl-19,26,2-trinor-vitamin D analogs |
| MX2008012671A (es) | 2006-04-06 | 2008-10-15 | Wisconsin Alumni Res Found | Analogos 1 a,25-dihidroxi- 19, 26,27-trinor vitamina d 2-sustituidos y sus usos. |
| WO2008026078A2 (en) * | 2006-04-06 | 2008-03-06 | Wisconsin Alumni Research Foundation | 19-nor-vitamin d analogs with 1,2,or 3,2 heterocyclic ring |
| AU2007298651A1 (en) * | 2006-04-06 | 2008-03-27 | Wisconsin Alumni Research Foundation | 2-methylene-1 alpha-hydroxy-18,19,21-trinorvitamin D3 analogs and uses thereof |
| DE602007012216D1 (de) * | 2006-04-10 | 2011-03-10 | Wisconsin Alumni Res Found | 1-alpha-hydroxy-2-(3'-hydroxypropyliden)-19-nor-vitamin-d-verbindungen mit einer 1,1-dimethylpropyl-seitenkette |
| CA2710970A1 (en) * | 2007-12-28 | 2009-07-09 | Wisconsin Alumni Research Foundation | 2-methylene-(20s,25r)-19,26-dinor-vitamin d analogs |
| EP2240440A2 (en) * | 2007-12-28 | 2010-10-20 | Wisconsin Alumni Research Foundation | 2-methylene-(20s,25s)-19,26-dinor-vitamin d analogs |
| US7648974B1 (en) * | 2008-07-10 | 2010-01-19 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D analogs with 3,2-dihydrofuran ring |
| US7879829B2 (en) * | 2008-07-10 | 2011-02-01 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D analogs with 1,2-dihydrofuran ring |
| US8193170B2 (en) | 2008-07-10 | 2012-06-05 | Wisconsin Alumni Research Foundation | 2-methylene-19,26-dinor-(20R,22E,25R)-vitamin D analogs |
| US8399439B2 (en) | 2008-07-10 | 2013-03-19 | Wisconsin Alumni Research Foundation | 2-methylene-19,26-dinor-(20S,22E,25R)-vitamin D analogs |
| US8217023B2 (en) | 2009-10-02 | 2012-07-10 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D analogs with 1,2- or 3,2-cyclopentene ring |
| EP2525799B1 (en) | 2009-10-02 | 2014-09-03 | Wisconsin Alumni Research Foundation | (20s,22e)-2-methylene-19-nor-22-ene-1alpha,25-dihydroxyvitamin d3 analogs |
| MX339926B (es) * | 2010-09-30 | 2016-06-16 | Wisconsin Alumni Res Found * | (20r, 25s)-metilen-19,26-dinor-1a,25-dihidroxivitamina d3 en forma cristalina. |
| JP6035331B2 (ja) * | 2011-06-14 | 2016-11-30 | ウイスコンシン アラムニ リサーチ ファンデーション | ３−デスオキシ−２−メチレン−１９−ノル−ビタミンｄ類似体およびそれらの使用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4666634A (en) | 1984-12-05 | 1987-05-19 | Chugai Seiyaku Kabushiki Kaisha | vitamin D3 derivatives having a substituent at 2-position |
| US5086191A (en) | 1991-05-28 | 1992-02-04 | Wisconsin Alumni Research Foundation | Intermediates for the synthesis of 19-nor vitamin D compounds |
| DE69400495T2 (de) | 1993-04-05 | 1997-04-30 | Wisconsin Alumni Res Found | 19-Nor-vitamin-D3-Verbindung mit einem Substituent an die 2. Stelle |
| US5552392A (en) | 1993-11-03 | 1996-09-03 | Wisconsin Alumni Research Foundation | Method of treating hypoparathyroidism with (20S) vitamin D compounds |
| US5945410A (en) | 1997-03-17 | 1999-08-31 | Wisconsin Alumni Research Foundation | 2-alkyl-19-nor-vitamin D compounds |
| US5843928A (en) * | 1997-03-17 | 1998-12-01 | Wisconsin Alumni Research Foundation | 2-alkylidene-19-nor-vitamin D compounds |
| US6392071B1 (en) | 1997-03-17 | 2002-05-21 | Wisconsin Alumni: Research Foundation | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds |
| US6306844B1 (en) * | 1997-03-17 | 2001-10-23 | Wisconsin Alumni Research Foundation | Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength |
| US6806262B2 (en) * | 2000-05-31 | 2004-10-19 | Wisconsin Alumni Research Foundation | 2-ethyl and 2-ethylidene-19-nor-vitamin D compounds |
| WO2002020021A1 (en) | 2000-09-08 | 2002-03-14 | Wisconsin Alumni Research Foundation | 1alpha-hydroxy-2-methylene-19-nor-homopregnacalciferol and its therapeutic applications |
| WO2002094247A2 (en) | 2001-05-22 | 2002-11-28 | Bioxell S.P.A. | Use of a vitamin d3 analogue for the treatment of autoimmune diabetes |
| US6627622B2 (en) * | 2002-02-18 | 2003-09-30 | Wisconsin Alumni Research Foundation | (20S)-1α-hydroxy-2-methylene-19-nor-bishomopregnacalciferol and its uses |
| US6566352B1 (en) | 2002-02-18 | 2003-05-20 | Wisconsin Alumni Research Foudation | 1 α-hydroxy-2-methylene-19-nor-pregnacalciferol and its uses |
| US20030195175A1 (en) | 2002-03-25 | 2003-10-16 | Deluca Hector F. | Use of carbon-2-modified-vitamin D analogs to induce the formation of new bone |
| GB0305332D0 (en) | 2003-03-10 | 2003-04-09 | Leuven K U Res & Dev | Biological evaluation of novel vitamin D analogues |
| US6894037B2 (en) * | 2003-07-03 | 2005-05-17 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses |
| US20050009792A1 (en) | 2003-07-08 | 2005-01-13 | Deluca Hector F. | (20S)-1alpha-hydroxy-2-methylene-19-nor-vitamin D3 and its uses |
| CA2539361A1 (en) | 2003-09-19 | 2005-03-31 | Pfizer Products Inc. | Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and an estrogen agonist/antagonist |
| US7053075B2 (en) | 2003-11-25 | 2006-05-30 | Deluca Hector F | Methods for reducing body fat using vitamin D compounds |
| CA2544502A1 (en) | 2003-11-25 | 2005-06-09 | Wisconsin Alumni Research Foundation | Vitamin d analogs for obesity prevention and treatment |
| JP2008520689A (ja) * | 2004-11-22 | 2008-06-19 | ウィスコンシン・アルムニ・リサーチ・ファウンデーション | １９，２６，２７−トリノル−（２０Ｓ）−１α−ヒドロキシビタミンＤ３の２α−メチルおよび２β−メチル類似体およびそれらの使用 |
| AU2006230296B2 (en) * | 2005-03-29 | 2011-07-07 | Wisconsin Alumni Research Foundation | 2-methylene-19-nor-(23s)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone and 2-methylene-19-nor-(23R)-25-dehydro-1alpha-hydroxyvitamin D3-26,23-lactone |
| CA2605727A1 (en) | 2005-05-03 | 2006-11-09 | Wisconsin Alumni Research Foundation | 19,26,27-trinor-1.alpha.,25-dihydroxyvitamin d3 compounds |
| US7528122B2 (en) * | 2006-02-02 | 2009-05-05 | Wisconsin Alumni Research Foundation | Vitamin D analog—NEL, methods and uses thereof |
| CA2646909A1 (en) * | 2006-04-06 | 2008-03-27 | Hector F. Deluca | 2-methylene-1alpha-hydroxy-19,21-dinorvitamin d3 analogs and uses thereof |
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2007
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- 2007-01-31 WO PCT/US2007/061404 patent/WO2007092721A2/en not_active Ceased
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- 2007-01-31 AU AU2007212185A patent/AU2007212185B2/en not_active Ceased
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- 2007-01-31 AT AT07763622T patent/ATE451352T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
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| US20070191317A1 (en) | 2007-08-16 |
| CA2637302A1 (en) | 2007-08-16 |
| US7803789B2 (en) | 2010-09-28 |
| AU2007212185B2 (en) | 2011-07-21 |
| DE602007003691D1 (de) | 2010-01-21 |
| EP1984329A2 (en) | 2008-10-29 |
| EP1984329B1 (en) | 2009-12-09 |
| CA2637302C (en) | 2014-04-01 |
| ES2339402T3 (es) | 2010-05-19 |
| AU2007212185A1 (en) | 2007-08-16 |
| WO2007092721A2 (en) | 2007-08-16 |
| JP2009525981A (ja) | 2009-07-16 |
| JP5113766B2 (ja) | 2013-01-09 |
| WO2007092721A8 (en) | 2008-10-09 |
| WO2007092721A3 (en) | 2007-10-18 |
| ATE451352T1 (de) | 2009-12-15 |
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