NZ543850A - Methods for identifying and using amyloid-inhibitory compounds - Google Patents

Methods for identifying and using amyloid-inhibitory compounds

Info

Publication number
NZ543850A
NZ543850A NZ543850A NZ54385000A NZ543850A NZ 543850 A NZ543850 A NZ 543850A NZ 543850 A NZ543850 A NZ 543850A NZ 54385000 A NZ54385000 A NZ 54385000A NZ 543850 A NZ543850 A NZ 543850A
Authority
NZ
New Zealand
Prior art keywords
estrogen
levels
amyloid
ovx
animals
Prior art date
Application number
NZ543850A
Other languages
English (en)
Inventor
Suzana Petanesca
Donald E Frail
Sam Gandy
Original Assignee
Wyeth Corp
Res Found Mental Hygiene
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp, Res Found Mental Hygiene filed Critical Wyeth Corp
Publication of NZ543850A publication Critical patent/NZ543850A/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pathology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
NZ543850A 1999-11-05 2000-11-03 Methods for identifying and using amyloid-inhibitory compounds NZ543850A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16381999P 1999-11-05 1999-11-05
NZ518780A NZ518780A (en) 1999-11-05 2000-11-03 Use of estrogen compounds to reduce levels of amyloid-beta peptides and to treat disorders associated with amyloidosis such as Alzheimer's disease

Publications (1)

Publication Number Publication Date
NZ543850A true NZ543850A (en) 2009-03-31

Family

ID=22591720

Family Applications (3)

Application Number Title Priority Date Filing Date
NZ543850A NZ543850A (en) 1999-11-05 2000-11-03 Methods for identifying and using amyloid-inhibitory compounds
NZ518780A NZ518780A (en) 1999-11-05 2000-11-03 Use of estrogen compounds to reduce levels of amyloid-beta peptides and to treat disorders associated with amyloidosis such as Alzheimer's disease
NZ536461A NZ536461A (en) 1999-11-05 2000-11-03 Methods for identifying and using amyloid-inhibitory compounds

Family Applications After (2)

Application Number Title Priority Date Filing Date
NZ518780A NZ518780A (en) 1999-11-05 2000-11-03 Use of estrogen compounds to reduce levels of amyloid-beta peptides and to treat disorders associated with amyloidosis such as Alzheimer's disease
NZ536461A NZ536461A (en) 1999-11-05 2000-11-03 Methods for identifying and using amyloid-inhibitory compounds

Country Status (10)

Country Link
US (1) US20080085244A1 (https=)
EP (1) EP1272853A2 (https=)
JP (2) JP2003522737A (https=)
AR (1) AR027878A1 (https=)
AU (2) AU2005200176B2 (https=)
CA (1) CA2390161A1 (https=)
MX (1) MXPA02004480A (https=)
NZ (3) NZ543850A (https=)
TW (3) TWI265026B (https=)
WO (1) WO2001035106A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6815175B2 (en) 2001-03-16 2004-11-09 Cornell Research Foundation, Inc. Anti-amyloid peptide antibody based diagnosis and treatment of a neurological disease or disorder
BR0208165A (pt) * 2001-03-16 2004-03-30 Wyeth Corp Composições farmacêuticas e seus usos na terapia de reposição de estrogênio
WO2008150547A1 (en) 2007-06-04 2008-12-11 The Regents Of The University Of California Pregnancy hormone combination for treatment of autoimmune diseases
US20130203722A1 (en) 2006-09-26 2013-08-08 Rhonda R. Voskuhl Estriol therapy for autoimmune and neurodegenerative disease and disorders
US6936599B2 (en) 2001-04-25 2005-08-30 The Regents Of The University Of California Estriol therapy for multiple sclerosis and other autoimmune diseases
EP1371986A1 (en) * 2002-06-06 2003-12-17 ABETA GmbH Diagnosis of Alzheimer's disease based on the hAbeta42:hAbeta40 ratio
JP2007284351A (ja) * 2004-07-27 2007-11-01 Osaka Bioscience Institute アミロイド蛋白質の凝集を抑制する物質とその作用
CA2623839C (en) * 2005-09-26 2013-12-17 The Regents Of The University Of California Estriol therapy for autoimmune and neurodegenerataive diseases and disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4311870C2 (de) * 1993-04-10 1998-07-30 Altramed Holdings Ltd Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen
US5554601A (en) * 1993-11-05 1996-09-10 University Of Florida Methods for neuroprotection
US5552415A (en) * 1993-12-21 1996-09-03 Eli Lilly And Company Method of inhibiting Alzheimer's Disease
JP3552272B2 (ja) * 1994-05-27 2004-08-11 帝国臓器製薬株式会社 免疫化学的簡易アッセイ方法および装置
WO1997046664A1 (en) * 1996-06-06 1997-12-11 University Of Washington Perlecan transgenic animals and methods of identifying compounds for the treatment of amyloidoses
JPH1090261A (ja) * 1996-08-23 1998-04-10 Fuotoreru Patrick 性ステロイドホルモン測定用プレート、これを用いた測定キット及び測定法
US5898094A (en) * 1996-10-21 1999-04-27 University Of South Florida Transgenic mice expressing APPK670N,M671L and a mutant presenilin transgenes
WO1998043647A1 (en) * 1997-03-28 1998-10-08 Massachusetts Institute Of Technology, Inc. Regulation of amyloid precursor protein (app) expression by estrogenic compounds
WO1998048784A2 (en) * 1997-04-28 1998-11-05 The University Of British Columbia Method and composition for modulating amyloidosis
US6080778A (en) * 1998-03-23 2000-06-27 Children's Medical Center Corporation Methods for decreasing beta amyloid protein

Also Published As

Publication number Publication date
WO2001035106A3 (en) 2002-11-14
AU1459201A (en) 2001-06-06
NZ536461A (en) 2005-02-25
NZ518780A (en) 2006-02-24
US20080085244A1 (en) 2008-04-10
AU2005200176A1 (en) 2005-02-10
AR027878A1 (es) 2003-04-16
TWI302099B (en) 2008-10-21
TW200834074A (en) 2008-08-16
MXPA02004480A (es) 2004-09-10
TW200621221A (en) 2006-07-01
WO2001035106A2 (en) 2001-05-17
CA2390161A1 (en) 2001-05-17
AU2005200176B2 (en) 2007-10-25
JP2008058329A (ja) 2008-03-13
TWI265026B (en) 2006-11-01
JP2003522737A (ja) 2003-07-29
EP1272853A2 (en) 2003-01-08
AU779781B2 (en) 2005-02-10

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