NZ506204A - Advanced active devices and methods for molecular biological analysis and diagnostics - Google Patents

Advanced active devices and methods for molecular biological analysis and diagnostics

Info

Publication number
NZ506204A
NZ506204A NZ506204A NZ50620499A NZ506204A NZ 506204 A NZ506204 A NZ 506204A NZ 506204 A NZ506204 A NZ 506204A NZ 50620499 A NZ50620499 A NZ 50620499A NZ 506204 A NZ506204 A NZ 506204A
Authority
NZ
New Zealand
Prior art keywords
array
diagnostics
methods
materials
active devices
Prior art date
Application number
NZ506204A
Other languages
English (en)
Inventor
Donald E Ackley
Paul D Swanson
Scott O Graham
Elizabeth L Mather
Timothy L Leclair
William F Butler
Original Assignee
Nanogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/026,618 external-priority patent/US6099803A/en
Priority claimed from US09/240,920 external-priority patent/US6254827B1/en
Priority claimed from US09/239,598 external-priority patent/US6331274B1/en
Priority claimed from US09/239,569 external-priority patent/US6068818A/en
Priority claimed from US09/240,489 external-priority patent/US6225059B1/en
Priority claimed from US09/240,931 external-priority patent/US6315953B1/en
Application filed by Nanogen Inc filed Critical Nanogen Inc
Publication of NZ506204A publication Critical patent/NZ506204A/xx

Links

Classifications

    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009—RRAM elements whose operation depends upon chemical change
    • G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G11C13/0019—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material comprising bio-molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C13/00—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00
    • G11C13/0002—Digital stores characterised by the use of storage elements not covered by groups G11C11/00, G11C23/00, or G11C25/00 using resistive RAM [RRAM] elements
    • G11C13/0009—RRAM elements whose operation depends upon chemical change
    • G11C13/0014—RRAM elements whose operation depends upon chemical change comprising cells based on organic memory material
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C19/00—Digital stores in which the information is moved stepwise, e.g. shift registers
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L29/00—Semiconductor devices specially adapted for rectifying, amplifying, oscillating or switching and having potential barriers; Capacitors or resistors having potential barriers, e.g. a PN-junction depletion layer or carrier concentration layer; Details of semiconductor bodies or of electrodes thereof ; Multistep manufacturing processes therefor
    • H01L29/66—Types of semiconductor device ; Multistep manufacturing processes therefor
    • H01L29/66007—Multistep manufacturing processes
    • H01L29/66075—Multistep manufacturing processes of devices having semiconductor bodies comprising group 14 or group 13/15 materials
    • H01L29/66227—Multistep manufacturing processes of devices having semiconductor bodies comprising group 14 or group 13/15 materials the devices being controllable only by the electric current supplied or the electric potential applied, to an electrode which does not carry the current to be rectified, amplified or switched, e.g. three-terminal devices
    • H01L29/66409—Unipolar field-effect transistors
    • H01L29/66477—Unipolar field-effect transistors with an insulated gate, i.e. MISFET
    • H01L29/6656—Unipolar field-effect transistors with an insulated gate, i.e. MISFET using multiple spacer layers, e.g. multiple sidewall spacers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
    • H01L2924/0001—Technical content checked by a classifier
    • H01L2924/0002—Not covered by any one of groups H01L24/00, H01L24/00 and H01L2224/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Power Engineering (AREA)
  • Nanotechnology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Mathematical Physics (AREA)
  • Manufacturing & Machinery (AREA)
  • Ceramic Engineering (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Computer Hardware Design (AREA)
  • Fluid Mechanics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ506204A 1998-02-20 1999-02-11 Advanced active devices and methods for molecular biological analysis and diagnostics NZ506204A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US09/026,618 US6099803A (en) 1994-07-07 1998-02-20 Advanced active electronic devices for molecular biological analysis and diagnostics
US09/240,920 US6254827B1 (en) 1993-11-01 1999-01-29 Methods for fabricating multi-component devices for molecular biological analysis and diagnostics
US09/239,598 US6331274B1 (en) 1993-11-01 1999-01-29 Advanced active circuits and devices for molecular biological analysis and diagnostics
US09/239,569 US6068818A (en) 1993-11-01 1999-01-29 Multicomponent devices for molecular biological analysis and diagnostics
US09/240,489 US6225059B1 (en) 1993-11-01 1999-01-29 Advanced active electronic devices including collection electrodes for molecular biological analysis and diagnostics
US09/240,931 US6315953B1 (en) 1993-11-01 1999-01-29 Devices for molecular biological analysis and diagnostics including waveguides
PCT/US1999/003080 WO1999042558A1 (en) 1998-02-20 1999-02-11 Advanced active devices and methods for molecular biological analysis and diagnostics

Publications (1)

Publication Number Publication Date
NZ506204A true NZ506204A (en) 2003-06-30

Family

ID=27556084

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ506204A NZ506204A (en) 1998-02-20 1999-02-11 Advanced active devices and methods for molecular biological analysis and diagnostics

Country Status (9)

Country Link
EP (1) EP1054949A4 (xx)
JP (1) JP2003524750A (xx)
KR (1) KR20010041147A (xx)
CN (1) CN1237165C (xx)
AU (1) AU742960B2 (xx)
BR (1) BR9909207A (xx)
CA (1) CA2320798C (xx)
NZ (1) NZ506204A (xx)
WO (1) WO1999042558A1 (xx)

Families Citing this family (25)

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Publication number Priority date Publication date Assignee Title
US6379897B1 (en) 2000-11-09 2002-04-30 Nanogen, Inc. Methods for gene expression monitoring on electronic microarrays
JP2003507714A (ja) * 1999-08-13 2003-02-25 ナノゲン・インコーポレイテッド 分子間リガンド結合構造のコンビナトーリアル選択および薬物スクリーニングのためのマイクロエレクトロニック分子ディスクリプターアレイのデバイス、方法、操作およびフォーマット
WO2001016857A2 (en) * 1999-08-27 2001-03-08 Pluvita Corporation System and method for genomic and proteomic agricultural disease assessment via expression profile comparison
US6589778B1 (en) 1999-12-15 2003-07-08 Amersham Biosciences Ab Method and apparatus for performing biological reactions on a substrate surface
US6569674B1 (en) 1999-12-15 2003-05-27 Amersham Biosciences Ab Method and apparatus for performing biological reactions on a substrate surface
WO2001044515A2 (en) * 1999-12-15 2001-06-21 Motorola, Inc. Apparatus for performing biological reactions
DE10015818A1 (de) * 2000-03-30 2001-10-18 Infineon Technologies Ag Biosensor und Verfahren zum Ermitteln makromolekularer Biopolymere mit einem Biosensor
DE10049901C2 (de) * 2000-10-10 2003-01-02 Aventis Res & Tech Gmbh & Co Vorrichtung und Verfahren zur elektrisch beschleunigten Immobilisierung und zur Detektion von Molekülen
US7018402B2 (en) 2001-03-09 2006-03-28 Georgia Tech Research Corporation Intravascular device and method for axially stretching blood vessels
DE10122659A1 (de) * 2001-05-10 2002-12-05 Infineon Technologies Ag Biochip-Anordnung
US6893822B2 (en) 2001-07-19 2005-05-17 Nanogen Recognomics Gmbh Enzymatic modification of a nucleic acid-synthetic binding unit conjugate
US7198754B2 (en) 2001-08-31 2007-04-03 Kabushiki Kaisha Toshiba Biological material detection element, biological material detection method and apparatus, charged material moving apparatus
JP3848226B2 (ja) * 2001-08-31 2006-11-22 株式会社東芝 生体物質検出装置及び生体物質検出素子
WO2003029830A1 (en) * 2001-10-03 2003-04-10 Genomic Solutions Acquisitions Limited Cleaning method
GB0200705D0 (en) * 2002-01-14 2002-02-27 Univ Cambridge Tech Fluid movement
GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
CN1429917A (zh) * 2002-10-11 2003-07-16 薛永新 艾滋病毒原位核酸芯片及其制备方法
DE102004010635B4 (de) * 2004-03-02 2006-10-05 Micronas Gmbh Vorrichtung zur Durchführung von Messungen an Biokomponenten
NL1031465C2 (nl) * 2006-03-30 2007-10-03 C2V B V Werkwijze voor het opbouwen van een inrichting met fluïdische en elektrische functies.
WO2008020364A2 (en) * 2006-08-14 2008-02-21 Koninklijke Philips Electronics N. V. Biochemical sensor device
EP2653861B1 (en) * 2006-12-14 2014-08-13 Life Technologies Corporation Method for sequencing a nucleic acid using large-scale FET arrays
CH701701A2 (de) * 2009-08-28 2011-02-28 Kgmed Gmbh Verfahren zur eichung einer diagnostischen messvorrichtung.
BR112020013397A2 (pt) 2018-01-08 2020-12-01 Quantum-Si Incorporated sistema e métodos para carregamento eletrocinético de câmaras de reação de escala por submícron
CN111229342B (zh) * 2020-01-17 2022-02-11 上海新微技术研发中心有限公司 基于cmos图像传感的光栅波导多微流道芯片的制造方法
CN112517093A (zh) * 2020-11-17 2021-03-19 四川大学 一种Fish唾液自动分样检测盘及其检测方法

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
EP0213825A3 (en) * 1985-08-22 1989-04-26 Molecular Devices Corporation Multiple chemically modulated capacitance
US4787963A (en) * 1987-05-04 1988-11-29 Syntro Corporation Method and means for annealing complementary nucleic acid molecules at an accelerated rate
EP0376611A3 (en) * 1988-12-30 1992-07-22 The Board Of Trustees Of The Leland Stanford Junior University Electrophoretic system
US5527681A (en) * 1989-06-07 1996-06-18 Affymax Technologies N.V. Immobilized molecular synthesis of systematically substituted compounds
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US5632957A (en) * 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
US5677195A (en) * 1991-11-22 1997-10-14 Affymax Technologies N.V. Combinatorial strategies for polymer synthesis
JPH05236997A (ja) * 1992-02-28 1993-09-17 Hitachi Ltd ポリヌクレオチド捕捉用チップ
US5728532A (en) * 1996-05-31 1998-03-17 Ackley; Donald E. Electrode configuration for matrix addressing of a molecular detection device

Also Published As

Publication number Publication date
CA2320798A1 (en) 1999-08-26
AU2763899A (en) 1999-09-06
CN1237165C (zh) 2006-01-18
CN1296525A (zh) 2001-05-23
CA2320798C (en) 2008-01-15
KR20010041147A (ko) 2001-05-15
WO1999042558A1 (en) 1999-08-26
EP1054949A4 (en) 2006-09-27
EP1054949A1 (en) 2000-11-29
BR9909207A (pt) 2001-11-06
AU742960B2 (en) 2002-01-17
JP2003524750A (ja) 2003-08-19

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