NZ331432A - Process for the preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3 -difluoro-2-oxohexyl]-l-prolinamide - Google Patents

Process for the preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3 -difluoro-2-oxohexyl]-l-prolinamide

Info

Publication number
NZ331432A
NZ331432A NZ331432A NZ33143297A NZ331432A NZ 331432 A NZ331432 A NZ 331432A NZ 331432 A NZ331432 A NZ 331432A NZ 33143297 A NZ33143297 A NZ 33143297A NZ 331432 A NZ331432 A NZ 331432A
Authority
NZ
New Zealand
Prior art keywords
aminoiminomethyl
prolinamide
oxohexyl
phenylalanyl
difluoro
Prior art date
Application number
NZ331432A
Other languages
English (en)
Inventor
Duane Eric Rudisell
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NZ331432A publication Critical patent/NZ331432A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ331432A 1996-03-26 1997-02-25 Process for the preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3 -difluoro-2-oxohexyl]-l-prolinamide NZ331432A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62472196A 1996-03-26 1996-03-26
PCT/US1997/002869 WO1997035874A1 (en) 1996-03-26 1997-02-25 Process for the preparation of n-methyl-d-phenylalanyl-n-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3-difluoro-2-oxohexyl]-l-prolinamide

Publications (1)

Publication Number Publication Date
NZ331432A true NZ331432A (en) 2000-03-27

Family

ID=24503070

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ331432A NZ331432A (en) 1996-03-26 1997-02-25 Process for the preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3 -difluoro-2-oxohexyl]-l-prolinamide

Country Status (13)

Country Link
EP (1) EP1012165A1 (pt)
JP (1) JP2000507267A (pt)
KR (1) KR20000004991A (pt)
CN (1) CN1121410C (pt)
AR (1) AR006366A1 (pt)
AU (1) AU710040B2 (pt)
BR (1) BR9708369A (pt)
CA (1) CA2250583C (pt)
IL (1) IL126071A (pt)
NO (1) NO984490L (pt)
NZ (1) NZ331432A (pt)
WO (1) WO1997035874A1 (pt)
ZA (1) ZA972506B (pt)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0503203A1 (en) * 1991-03-15 1992-09-16 Merrell Dow Pharmaceuticals Inc. Novel thrombin inhibitors

Also Published As

Publication number Publication date
ZA972506B (en) 1997-09-26
CA2250583C (en) 2003-01-14
AR006366A1 (es) 1999-08-25
IL126071A (en) 2003-06-24
KR20000004991A (ko) 2000-01-25
JP2000507267A (ja) 2000-06-13
IL126071A0 (en) 1999-05-09
CN1214691A (zh) 1999-04-21
NO984490D0 (no) 1998-09-25
NO984490L (no) 1998-09-25
CN1121410C (zh) 2003-09-17
AU710040B2 (en) 1999-09-09
WO1997035874A1 (en) 1997-10-02
EP1012165A1 (en) 2000-06-28
BR9708369A (pt) 1999-08-03
CA2250583A1 (en) 1997-10-02
AU2055097A (en) 1997-10-17

Similar Documents

Publication Publication Date Title
CA2168829A1 (en) Paroxetine hydrochloride anhydrate forms a,b,c and d
CA2195677A1 (en) Endothelin antagonists
IN2012DE00109A (pt)
AU1423795A (en) Treatment of normotensive glaucoma with angiotensin ii antagonists
ZA961074B (en) Chiral Methylphenyloxazolidinones.
SE9903291D0 (sv) New process
PL337648A1 (en) (+)-norcisapride useful in case of disorders occurring under mediation of 5-ht3 and 5-ht4
IL122606A0 (en) (S)-hydroxy-nitrile-lyase
MY120237A (en) Method for the synthesis of quinoline derivatives
NZ331432A (en) Process for the preparation of N-methyl-D-phenylalanyl-N-[1-[3-[(aminoiminomethyl)amino]propyl]-3,3 -difluoro-2-oxohexyl]-l-prolinamide
MY119686A (en) Sequential distillation process for removing tetrahydroazepine from aminocapronitrile and/or hexamethylenediamine
EP0684271A3 (de) Verfahren zur Herstellung von Polyamiden auf Basis von alpha,w-Dinitrilen.
LTIP1958A (en) New use of ropivacaine
SE9800865D0 (sv) New Process
CA2298805A1 (en) Method for preparing 3-cyano-2,4-dihalogen-5-fluor-benzoic acid
GB9318790D0 (en) Heterocyclic derivatives
CA2328832A1 (en) Processes for preparing pesticidal intermediates
CA2190952A1 (en) Use of a naphthalenesulfonic acid compound for inhibiting retroviral infection
IL116262A0 (en) Processes for preparing ranitidine
CA2175420A1 (en) Process for the preparation of optionally 2-substituted 5-chloroimidazole-4-carbaldehydes
CA2338649A1 (en) New phenylethylamine derivatives, processes for preparing them and their use as pharmaceutical compositions
ZA991107B (en) Process for preparing 3-hydroxy-5-[(1,4,5,6-tetrahydro-5-hydroxy-2-pyrimidinyl)amino] benzoic acid.
TW427981B (en) Processes and intermediates in the synthesis of 5-(3-[-exo-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-one
GR3035504T3 (en) Dimethyl-substituted cyclohexane diene derivatives
MX9701865A (es) Compuestos de dimetil-(3-aril-but-3-enil)-amino como ingredientes activos farmaceuticos.

Legal Events

Date Code Title Description
RENW Renewal (renewal fees accepted)