NZ261308A - 2,2-(carbonyl-bis(imino-n-methyl-4,2-pyrrolecarbonylimino(n-methyl-4,2-pyrr ole)carbonylimino))-bis(1,5-naphthalenedisulphonic acid) and intermediate - Google Patents

2,2-(carbonyl-bis(imino-n-methyl-4,2-pyrrolecarbonylimino(n-methyl-4,2-pyrr ole)carbonylimino))-bis(1,5-naphthalenedisulphonic acid) and intermediate

Info

Publication number
NZ261308A
NZ261308A NZ261308A NZ26130894A NZ261308A NZ 261308 A NZ261308 A NZ 261308A NZ 261308 A NZ261308 A NZ 261308A NZ 26130894 A NZ26130894 A NZ 26130894A NZ 261308 A NZ261308 A NZ 261308A
Authority
NZ
New Zealand
Prior art keywords
bis
methyl
imino
carbonyl
pyrrole
Prior art date
Application number
NZ261308A
Other languages
English (en)
Inventor
Nicola Mongelli
Giovanni Biasoli
Mariangela Mariani
Francesco Sola
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of NZ261308A publication Critical patent/NZ261308A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NZ261308A 1993-03-05 1994-01-31 2,2-(carbonyl-bis(imino-n-methyl-4,2-pyrrolecarbonylimino(n-methyl-4,2-pyrr ole)carbonylimino))-bis(1,5-naphthalenedisulphonic acid) and intermediate NZ261308A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939304589A GB9304589D0 (en) 1993-03-05 1993-03-05 Biologically active ureido derivatives useful as antimetastic agents

Publications (1)

Publication Number Publication Date
NZ261308A true NZ261308A (en) 1996-02-27

Family

ID=10731580

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ261308A NZ261308A (en) 1993-03-05 1994-01-31 2,2-(carbonyl-bis(imino-n-methyl-4,2-pyrrolecarbonylimino(n-methyl-4,2-pyrr ole)carbonylimino))-bis(1,5-naphthalenedisulphonic acid) and intermediate

Country Status (17)

Country Link
US (1) US5534539A (OSRAM)
EP (1) EP0639073A1 (OSRAM)
JP (1) JPH07506594A (OSRAM)
KR (1) KR950701217A (OSRAM)
CN (1) CN1103533A (OSRAM)
AU (1) AU669269B2 (OSRAM)
CA (1) CA2134098A1 (OSRAM)
FI (1) FI945164A0 (OSRAM)
GB (1) GB9304589D0 (OSRAM)
HU (1) HUT71400A (OSRAM)
IL (1) IL108665A (OSRAM)
MY (1) MY110004A (OSRAM)
NZ (1) NZ261308A (OSRAM)
PL (1) PL305981A1 (OSRAM)
TW (1) TW262465B (OSRAM)
WO (1) WO1994020095A1 (OSRAM)
ZA (1) ZA941126B (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9403909D0 (en) * 1994-03-01 1994-04-20 Erba Carlo Spa Ureido derivatives of naphthalenephosphonic acids and process for their preparation
GB9504065D0 (en) * 1995-03-01 1995-04-19 Pharmacia Spa Poly-pyrrolecarboxamidonaphthalenic acid derivatives
GB9602721D0 (en) * 1996-02-09 1996-04-10 Pharmacia Spa Biologically active ureido derivatives useful in the treatment of multiple sclerosis
WO1999027939A1 (en) 1997-12-04 1999-06-10 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Ureido derivatives of poly-4-amino-2-carboxy-1-methyl pyrrole compounds for inhibition of inflammation
GB9727524D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Synergistic antitumor composition containing a biologically active ureido compound
WO1999058126A1 (en) * 1998-05-11 1999-11-18 The Endowment For Research In Human Biology, Inc. Use of neomycin for treating angiogenesis-related diseases
ATE435202T1 (de) * 2002-01-11 2009-07-15 Daiichi Sankyo Co Ltd Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung
CN1921847B (zh) 2004-02-24 2010-06-16 三共株式会社 氨基醇化合物
EP3381897A1 (en) 2017-03-27 2018-10-03 Leadiant Biosciences SA Derivatives of the disodium 2,2'-{carbonylbis[imino-3,1-phenylenecarbonylimino(1-methyl-1h-pyrrole-4,2-diyl)carbonylimino]}dinaphthalene-1,5-disulfonate salt and related compounds as heparanase inhibitors for the treatment of cancer
CN107235866B (zh) * 2017-06-13 2019-09-10 重庆医科大学 一种用于检测次磺酸化蛋白质的荧光探针、制备方法及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5012285A (en) * 1984-10-12 1986-05-02 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Use of suramin for clinical treatment of infection with any of the members of the family of human t-cell leukemia (htlv) viruses including lymphadenopathy virus (lav)
CA1308516C (en) * 1987-07-06 1992-10-06 J. William Lown Oligopeptide anticancer and antiviral agents
GB9000644D0 (en) * 1990-01-11 1990-03-14 Erba Carlo Spa New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds
GB9024738D0 (en) * 1990-11-14 1991-01-02 Erba Carlo Spa A new method of treatment of tumor necroisis factor(tnf)-related diseases
GB9116896D0 (en) * 1991-08-06 1991-09-18 Erba Carlo Spa 3-deoxymannosamine derivatives and process for their preparation
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives

Also Published As

Publication number Publication date
TW262465B (OSRAM) 1995-11-11
PL305981A1 (en) 1995-02-20
GB9304589D0 (en) 1993-04-21
IL108665A (en) 1997-03-18
ZA941126B (en) 1994-08-30
US5534539A (en) 1996-07-09
AU669269B2 (en) 1996-05-30
JPH07506594A (ja) 1995-07-20
EP0639073A1 (en) 1995-02-22
IL108665A0 (en) 1994-05-30
MY110004A (en) 1997-11-29
AU6000394A (en) 1994-09-26
FI945164A7 (fi) 1994-11-02
CN1103533A (zh) 1995-06-07
HUT71400A (en) 1995-11-28
FI945164A0 (fi) 1994-11-02
KR950701217A (ko) 1995-03-23
CA2134098A1 (en) 1994-09-15
WO1994020095A1 (en) 1994-09-15

Similar Documents

Publication Publication Date Title
US5420296A (en) Ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds
HK1006455B (en) Ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds
EP0937070B1 (en) Benzoheterocyclic distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
EP1064281B1 (en) Benzoheterocyclic distamycin derivatives, process for preparing them, and their use as antitumor agents
US6482920B1 (en) Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
NZ261308A (en) 2,2-(carbonyl-bis(imino-n-methyl-4,2-pyrrolecarbonylimino(n-methyl-4,2-pyrr ole)carbonylimino))-bis(1,5-naphthalenedisulphonic acid) and intermediate
EP1100777B1 (en) Sulfurated distamycin derivatives, process for preparing them, and their use as antitumor agents
US6753316B1 (en) Acryloyl derivatives analogous to distamycin, process for preparing them, and their use as antitumor agents
EP0787126A1 (en) Bis-(2-haloethyl)aminophenyl substituted distamycin derivatives as antitumor and antiviral agents
MXPA97001949A (en) Derivatives of distamycine substituted with bis- (2-haloethyl) aminophenylene as anatomy agents yantivira
EP1100778B1 (en) Oxidised sulfurated distamycin derivatives, process for preparing them, and their use as antitumor agents
EP1084120B1 (en) Cinnamoyl distamycin analogous derivatives, process for their preparation, and their use as antitumor agents
IL109235A (en) Pharmaceuticals containing a history of oreido for the treatment of diseases caused by the virus virus
GB2260134A (en) Derivatives of poly-5-amino-3-carboxy-1-methyl compounds