NZ221647A - Di- and triblock copolymers comprising polyalkylene oxide block and a block comprising glycolic acid ester and trimethylene carbonate linkages; slow release drug delivery systems - Google Patents
Di- and triblock copolymers comprising polyalkylene oxide block and a block comprising glycolic acid ester and trimethylene carbonate linkages; slow release drug delivery systemsInfo
- Publication number
- NZ221647A NZ221647A NZ221647A NZ22164787A NZ221647A NZ 221647 A NZ221647 A NZ 221647A NZ 221647 A NZ221647 A NZ 221647A NZ 22164787 A NZ22164787 A NZ 22164787A NZ 221647 A NZ221647 A NZ 221647A
- Authority
- NZ
- New Zealand
- Prior art keywords
- block
- acid ester
- drug delivery
- delivery systems
- glycolic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/64—Polyesters containing both carboxylic ester groups and carbonate groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/903,801 US4882168A (en) | 1986-09-05 | 1986-09-05 | Polyesters containing alkylene oxide blocks as drug delivery systems |
US06/903,797 US4716203A (en) | 1986-09-05 | 1986-09-05 | Diblock and triblock copolymers |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ221647A true NZ221647A (en) | 1990-09-26 |
Family
ID=27129378
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ221647A NZ221647A (en) | 1986-09-05 | 1987-09-02 | Di- and triblock copolymers comprising polyalkylene oxide block and a block comprising glycolic acid ester and trimethylene carbonate linkages; slow release drug delivery systems |
Country Status (13)
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL9401703A (nl) * | 1994-10-14 | 1996-05-01 | Rijksuniversiteit | Kauwgom. |
US5665428A (en) * | 1995-10-25 | 1997-09-09 | Macromed, Inc. | Preparation of peptide containing biodegradable microspheres by melt process |
US5702717A (en) * | 1995-10-25 | 1997-12-30 | Macromed, Inc. | Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers |
DE19726412A1 (de) * | 1997-06-21 | 1998-12-24 | Merck Patent Gmbh | Implantatmaterial mit einer Träger-Wirkstoff-Kombination |
DE69829204T2 (de) * | 1997-10-03 | 2005-12-15 | Macromed Inc., Salt Lake City | Biologisch abbaubare triblock-poly(lactide-co-glycolide)-polyethylenglycol-copolymere mit umgekehrter thermischer gelierung |
US6117949A (en) * | 1998-10-01 | 2000-09-12 | Macromed, Inc. | Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
US6004573A (en) * | 1997-10-03 | 1999-12-21 | Macromed, Inc. | Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
US6201072B1 (en) | 1997-10-03 | 2001-03-13 | Macromed, Inc. | Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
US7662409B2 (en) | 1998-09-25 | 2010-02-16 | Gel-Del Technologies, Inc. | Protein matrix materials, devices and methods of making and using thereof |
US7018645B1 (en) | 2000-04-27 | 2006-03-28 | Macromed, Inc. | Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties |
EA007772B1 (ru) * | 2001-03-23 | 2007-02-27 | Гумлинк А/С | Разлагаемый заменитель смолы для жевательной резинки |
US7507427B2 (en) | 2001-03-23 | 2009-03-24 | Gumlink A/S | Coated degradable chewing gum with improved shelf life and process for preparing same |
CA2451187C (en) | 2001-06-22 | 2012-08-14 | Southern Biosystems, Inc. | Zero-order prolonged release coaxial implants |
ATE391742T1 (de) * | 2002-02-15 | 2008-04-15 | Nektar Therapeutics Al Corp | Hydrolytisch abbaubare polyalkylenoxid-polymere |
AU2003225212A1 (en) | 2002-04-29 | 2003-11-17 | Gel-Del Technologies, Inc. | Biomatrix structural containment and fixation systems and methods of use thereof |
WO2003093344A1 (en) * | 2002-05-03 | 2003-11-13 | Janssen Pharmaceutica N.V. | Polymeric microemulsions |
US7649023B2 (en) | 2002-06-11 | 2010-01-19 | Novartis Ag | Biodegradable block copolymeric compositions for drug delivery |
EP1534340B1 (en) | 2002-09-06 | 2011-11-16 | Cerulean Pharma Inc. | Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto |
AU2002340774B2 (en) | 2002-09-24 | 2008-10-02 | Gumlink A/S | Chewing gum comprising at least two different biodegradable polymers |
CA2500022C (en) | 2002-09-24 | 2011-02-22 | Gumlink A/S | Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer |
ES2312741T3 (es) | 2003-05-06 | 2009-03-01 | Gumlink A/S | Procedimiento para producir granulos de goma de mascar y granulos de goma comprimidos, y un equipo para granular goma de mascar. |
EP1474995B1 (en) | 2003-05-06 | 2012-11-14 | Gumlink A/S | A method for producing chewing gum granules, a gum composition extruder and granulating system, and a chewing gum product |
US8465537B2 (en) | 2003-06-17 | 2013-06-18 | Gel-Del Technologies, Inc. | Encapsulated or coated stent systems |
CA2537315C (en) | 2003-08-26 | 2015-12-08 | Gel-Del Technologies, Inc. | Protein biomaterials and biocoacervates and methods of making and using thereof |
US8529939B2 (en) | 2003-12-08 | 2013-09-10 | Gel-Del Technologies, Inc. | Mucoadhesive drug delivery devices and methods of making and using thereof |
JP2010516625A (ja) | 2007-01-24 | 2010-05-20 | インサート セラピューティクス, インコーポレイテッド | 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート |
AU2008345047A1 (en) | 2007-12-26 | 2009-07-09 | Gel-Del Technologies, Inc. | Biocompatible protein particles, particle devices and methods thereof |
US10016534B2 (en) | 2008-11-17 | 2018-07-10 | Gel-Del Technologies, Inc. | Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof |
CN102666533A (zh) | 2009-09-15 | 2012-09-12 | 天蓝制药公司 | 癌症治疗 |
EA035193B1 (ru) | 2010-05-18 | 2020-05-14 | Серулин Фарма Инк. | Композиции и способы лечения аутоиммунных и других заболеваний |
US20140094432A1 (en) | 2012-10-02 | 2014-04-03 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
EP4192509A1 (en) | 2020-08-05 | 2023-06-14 | Ellipses Pharma Ltd | Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3736646A (en) * | 1971-10-18 | 1973-06-05 | American Cyanamid Co | Method of attaching surgical needles to multifilament polyglycolic acid absorbable sutures |
US4047533A (en) * | 1976-09-20 | 1977-09-13 | American Cyanamid Company | Absorbable surgical sutures coated with polyoxyethylene-polyoxypropylene copolymer lubricant |
US4429080A (en) * | 1982-07-01 | 1984-01-31 | American Cyanamid Company | Synthetic copolymer surgical articles and method of manufacturing the same |
US4452973A (en) * | 1982-11-12 | 1984-06-05 | American Cyanamid Company | Poly(glycolic acid)/poly(oxyethylene) triblock copolymers and method of manufacturing the same |
US4438253A (en) * | 1982-11-12 | 1984-03-20 | American Cyanamid Company | Poly(glycolic acid)/poly(alkylene glycol) block copolymers and method of manufacturing the same |
-
1987
- 1987-08-25 EP EP87112279A patent/EP0258780B1/en not_active Expired - Lifetime
- 1987-08-25 DE DE87112279T patent/DE3786309T2/de not_active Expired - Fee Related
- 1987-08-25 ES ES87112279T patent/ES2058081T3/es not_active Expired - Lifetime
- 1987-09-02 NZ NZ221647A patent/NZ221647A/xx unknown
- 1987-09-03 IL IL83764A patent/IL83764A/xx not_active IP Right Cessation
- 1987-09-03 CA CA000546072A patent/CA1283988C/en not_active Expired - Fee Related
- 1987-09-04 KR KR870009842A patent/KR880003985A/ko not_active Application Discontinuation
- 1987-09-04 BR BR8704648A patent/BR8704648A/pt not_active Application Discontinuation
- 1987-09-04 AU AU77970/87A patent/AU605172B2/en not_active Ceased
- 1987-09-04 HU HU873970A patent/HU205711B/hu not_active IP Right Cessation
- 1987-09-04 DK DK462287A patent/DK462287A/da not_active Application Discontinuation
- 1987-09-04 FI FI873840A patent/FI873840A/fi not_active Application Discontinuation
-
1993
- 1993-07-16 GR GR920403165T patent/GR3008526T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI873840A (fi) | 1988-03-06 |
DK462287D0 (da) | 1987-09-04 |
EP0258780A2 (en) | 1988-03-09 |
EP0258780B1 (en) | 1993-06-23 |
HU205711B (en) | 1992-06-29 |
DK462287A (da) | 1988-03-06 |
BR8704648A (pt) | 1988-04-26 |
DE3786309D1 (de) | 1993-07-29 |
FI873840A0 (fi) | 1987-09-04 |
ES2058081T3 (es) | 1994-11-01 |
AU7797087A (en) | 1988-03-10 |
IL83764A (en) | 1991-05-12 |
DE3786309T2 (de) | 1994-02-10 |
KR880003985A (ko) | 1988-05-31 |
IL83764A0 (en) | 1988-02-29 |
AU605172B2 (en) | 1991-01-10 |
EP0258780A3 (en) | 1988-05-18 |
GR3008526T3 (US07498051-20090303-C00003.png) | 1993-10-29 |
CA1283988C (en) | 1991-05-07 |
HUT52945A (en) | 1990-09-28 |
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