NZ207962A - Synergistic pharmaceutical compositions for treatment of seizure disorders - Google Patents

Synergistic pharmaceutical compositions for treatment of seizure disorders

Info

Publication number
NZ207962A
NZ207962A NZ207962A NZ20796284A NZ207962A NZ 207962 A NZ207962 A NZ 207962A NZ 207962 A NZ207962 A NZ 207962A NZ 20796284 A NZ20796284 A NZ 20796284A NZ 207962 A NZ207962 A NZ 207962A
Authority
NZ
New Zealand
Prior art keywords
seizures
glycine
gvg
sarcosine
gaba
Prior art date
Application number
NZ207962A
Other languages
English (en)
Inventor
N Seiler
S Sarhan
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NZ207962A publication Critical patent/NZ207962A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ207962A 1983-04-29 1984-04-26 Synergistic pharmaceutical compositions for treatment of seizure disorders NZ207962A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838311804A GB8311804D0 (en) 1983-04-29 1983-04-29 Treatment of seizure disorders and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
NZ207962A true NZ207962A (en) 1986-12-05

Family

ID=10541938

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ207962A NZ207962A (en) 1983-04-29 1984-04-26 Synergistic pharmaceutical compositions for treatment of seizure disorders

Country Status (15)

Country Link
US (1) US4540582A (da)
EP (1) EP0124091B1 (da)
JP (1) JPS59206309A (da)
AT (1) ATE48759T1 (da)
AU (1) AU563291B2 (da)
CA (1) CA1228818A (da)
DE (1) DE3480764D1 (da)
DK (1) DK160805C (da)
GB (2) GB8311804D0 (da)
GR (1) GR81966B (da)
IE (1) IE57286B1 (da)
IL (1) IL71650A (da)
NZ (1) NZ207962A (da)
PT (1) PT78492B (da)
ZA (1) ZA843032B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0575613B1 (de) * 1992-01-10 1998-07-22 KOMISSAROVA, Irina Alexeevna Verwendung der aminosäure glycin zur herstellung von arzneimitteln mit antistress-, stressschutz- und nootroper wirkung
ID27724A (id) * 1998-05-15 2001-04-26 Warner Lambert Co Penstabil sediaan parmasi dari turunan-turunan asam gamma-aminobutira dan proses pembuatannya
US6057368A (en) * 1998-08-05 2000-05-02 Brookhaven Science Associates Llc Treatment of addiction and addiction-related behavior
US6541520B1 (en) 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
US6890951B2 (en) 1998-08-05 2005-05-10 Brookhaven Science Associates Llc Treatment of addiction and addiction-related behavior
US6395783B1 (en) 2000-10-23 2002-05-28 Brookhaven Science Associates, Llc Treatment of PCP addiction and PCP addiction-related behavior
US6713497B1 (en) * 2003-03-17 2004-03-30 Brookhaven Science Associates, Llc Use of vitamin B6 to mitigate visual field defects associated with the use of GABAergic drugs in mammals
EP1781279A2 (de) * 2004-06-11 2007-05-09 Egon Tech Präparat zur prophylaxe und therapie von stresszuständen, von funktionellen und organischen störungen des nervensystems und des stoffwechsels
WO2006075011A2 (en) * 2005-01-14 2006-07-20 N.V. Organon Glycine reuptake inhibitors for treating drug and alcohol dependence
US20160151316A1 (en) * 2012-01-27 2016-06-02 Catalyst Pharmaceutical Partners Method of treating tourette's disorder with gaba-aminotransferase inactivators
US10226442B2 (en) * 2017-07-10 2019-03-12 Syneurx International (Taiwan) Corp. Lithium salts of N-substituted glycine compounds and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1111433A (en) * 1965-08-25 1968-04-24 Zoja Lab Chim Farm A method to potentiate the activity of a group of sedative,hypnotic and narcotic compositions
US3960927A (en) * 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
FR2437834A1 (fr) * 1978-10-04 1980-04-30 Lejeune Jerome Compositions pharmaceutiques a base de l-serine ou de glycine
GB2120244B (en) * 1982-05-17 1985-05-01 Merrell Toraude & Co Aminoalkadiene derivative

Also Published As

Publication number Publication date
ZA843032B (en) 1984-11-28
EP0124091A3 (en) 1987-10-07
GB2138680B (en) 1986-05-21
IE841048L (en) 1984-10-29
US4540582A (en) 1985-09-10
EP0124091A2 (en) 1984-11-07
AU2644384A (en) 1984-11-01
GB2138680A (en) 1984-10-31
JPH0527606B2 (da) 1993-04-21
DK160805C (da) 1991-10-07
IL71650A0 (en) 1984-07-31
IE57286B1 (en) 1992-07-15
IL71650A (en) 1988-07-31
DK213484A (da) 1984-10-30
DK213484D0 (da) 1984-04-27
GB8311804D0 (en) 1983-06-02
DE3480764D1 (de) 1990-01-25
JPS59206309A (ja) 1984-11-22
EP0124091B1 (en) 1989-12-20
CA1228818A (en) 1987-11-03
ATE48759T1 (de) 1990-01-15
PT78492A (en) 1984-05-01
DK160805B (da) 1991-04-22
AU563291B2 (en) 1987-07-02
GB8410504D0 (en) 1984-05-31
GR81966B (da) 1984-12-12
PT78492B (en) 1986-06-11

Similar Documents

Publication Publication Date Title
US6562865B1 (en) Composition comprising a tramadol material and an anticonvulsant drug
USRE41920E1 (en) Isobutylgaba and its derivatives for the treatment of pain
US5605911A (en) Use of alpha-2 adrenergic drugs to prevent adverse effects of NMDA receptor hypofunction (NRH)
ES2500053T3 (es) Composición farmacéutica que comprende droxidopa para el tratamiento de la fibromialgia
AU765038B2 (en) Method for the treatment of insomnia
US5616580A (en) Pharmacological composition for preventing neurotoxic side effects of NMDA antagonists
DE69904922T2 (de) Pharmazeutische zusammensetzung zur behandlung von alkoholabhängigkeit, die opioid antagonisten mit nmda-rezeptorkomplex-modulatoren enthält
US4540582A (en) Treatment of seizure disorders and pharmaceutical compositions useful therein
MX2012007778A (es) Diazoxido para su uso en el tratamiento o prevencion de una enfermedad desmielinizante autoinmunitaria del sistema nervioso central (snc).
CA2332915C (en) Compositions comprising gaba analogs and caffeine
US4595697A (en) Treatment of seizure disorders and pharmaceutical compositions useful therein
US5049555A (en) Antagonists of specific excitatory amino acid receptors as neuroprotectants and anxiolytics
Watanabe et al. The role of spinal nitric oxide and glutamate in nociceptive behaviour evoked by high-dose intrathecal morphine in rats
US5616618A (en) Threo-3-(3,4-dihydroxyphenyl)serine analgesic composition
EP1084704B1 (en) Remedies for spinocerebellar ataxia and compositions for treating spinocerebellar ataxia
Seiler et al. Amplification by glycine of the anticonvulsant effect of THPO, a GABA uptake inhibitor
US20060199841A1 (en) Pharmaceutical combination for the treatment of spasticity and/or pain
US20220218635A1 (en) Ketone supplements-evoked effect on absence epilepsy by co-administration of uridine
RU2213561C2 (ru) Болеутоляющие композиции, содержащие ненаркотический анальгетик и усилитель анальгезии
UA128174C2 (uk) Фармацевтична комбінація, що містить тразодон для лікування невропатичного болю
JP2000072668A (ja) 神経保護剤