NZ199817A - Anthelmintic composition consisting of two components - Google Patents
Anthelmintic composition consisting of two componentsInfo
- Publication number
- NZ199817A NZ199817A NZ199817A NZ19981782A NZ199817A NZ 199817 A NZ199817 A NZ 199817A NZ 199817 A NZ199817 A NZ 199817A NZ 19981782 A NZ19981782 A NZ 19981782A NZ 199817 A NZ199817 A NZ 199817A
- Authority
- NZ
- New Zealand
- Prior art keywords
- benzimidazole
- composition
- anthelmintic
- chloro
- compounds
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims description 31
- 230000000507 anthelmentic effect Effects 0.000 title claims description 16
- 150000001875 compounds Chemical class 0.000 claims description 30
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 claims description 18
- 229940124339 anthelmintic agent Drugs 0.000 claims description 15
- 239000000921 anthelmintic agent Substances 0.000 claims description 15
- 239000003242 anti bacterial agent Substances 0.000 claims description 15
- 229940088710 antibiotic agent Drugs 0.000 claims description 15
- SKZKKFZAGNVIMN-UHFFFAOYSA-N Salicilamide Chemical compound NC(=O)C1=CC=CC=C1O SKZKKFZAGNVIMN-UHFFFAOYSA-N 0.000 claims description 9
- AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical compound C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 claims description 9
- 229960000581 salicylamide Drugs 0.000 claims description 9
- 150000002537 isoquinolines Chemical class 0.000 claims description 6
- -1 2-chloro-4-nitrophenyl Chemical group 0.000 claims description 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 5
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical compound NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 claims description 4
- 239000003120 macrolide antibiotic agent Substances 0.000 claims description 4
- WJCNZQLZVWNLKY-UHFFFAOYSA-N thiabendazole Chemical compound S1C=NC(C=2NC3=CC=CC=C3N=2)=C1 WJCNZQLZVWNLKY-UHFFFAOYSA-N 0.000 claims description 2
- YRWLZFXJFBZBEY-UHFFFAOYSA-N N-(6-butyl-1H-benzimidazol-2-yl)carbamic acid methyl ester Chemical compound CCCCC1=CC=C2N=C(NC(=O)OC)NC2=C1 YRWLZFXJFBZBEY-UHFFFAOYSA-N 0.000 claims 1
- MQXGOXSJWNZQNG-UHFFFAOYSA-N ethyl n-(6-ethoxy-1h-benzimidazol-2-yl)carbamate Chemical compound C1=C(OCC)C=C2NC(NC(=O)OCC)=NC2=C1 MQXGOXSJWNZQNG-UHFFFAOYSA-N 0.000 claims 1
- ZZUFCTLCJUWOSV-UHFFFAOYSA-N furosemide Chemical compound C1=C(Cl)C(S(=O)(=O)N)=CC(C(O)=O)=C1NCC1=CC=CO1 ZZUFCTLCJUWOSV-UHFFFAOYSA-N 0.000 claims 1
- 230000002195 synergetic effect Effects 0.000 claims 1
- 244000045947 parasite Species 0.000 description 18
- 241001465754 Metazoa Species 0.000 description 11
- 241000282472 Canis lupus familiaris Species 0.000 description 9
- 238000000862 absorption spectrum Methods 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 229960002669 albendazole Drugs 0.000 description 8
- HXHWSAZORRCQMX-UHFFFAOYSA-N albendazole Chemical compound CCCSC1=CC=C2NC(NC(=O)OC)=NC2=C1 HXHWSAZORRCQMX-UHFFFAOYSA-N 0.000 description 8
- FSVJFNAIGNNGKK-UHFFFAOYSA-N 2-[cyclohexyl(oxo)methyl]-3,6,7,11b-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4-one Chemical compound C1C(C2=CC=CC=C2CC2)N2C(=O)CN1C(=O)C1CCCCC1 FSVJFNAIGNNGKK-UHFFFAOYSA-N 0.000 description 7
- 229960001920 niclosamide Drugs 0.000 description 7
- RJMUSRYZPJIFPJ-UHFFFAOYSA-N niclosamide Chemical compound OC1=CC=C(Cl)C=C1C(=O)NC1=CC=C([N+]([O-])=O)C=C1Cl RJMUSRYZPJIFPJ-UHFFFAOYSA-N 0.000 description 7
- 229960002957 praziquantel Drugs 0.000 description 7
- 239000004480 active ingredient Substances 0.000 description 6
- 241000283707 Capra Species 0.000 description 5
- 241000242541 Trematoda Species 0.000 description 5
- 238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 5
- 238000004809 thin layer chromatography Methods 0.000 description 5
- 241001489151 Trichuris Species 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 4
- 241000243974 Haemonchus contortus Species 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 241000244206 Nematoda Species 0.000 description 3
- 241000242678 Schistosoma Species 0.000 description 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 3
- 241000187747 Streptomyces Species 0.000 description 3
- 238000011888 autopsy Methods 0.000 description 3
- 210000003608 fece Anatomy 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 239000007903 gelatin capsule Substances 0.000 description 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 241001147672 Ancylostoma caninum Species 0.000 description 2
- 241000244160 Echinococcus Species 0.000 description 2
- 241000243976 Haemonchus Species 0.000 description 2
- 241000404582 Hymenolepis <angiosperm> Species 0.000 description 2
- 241001137882 Nematodirus Species 0.000 description 2
- 241000510960 Oesophagostomum Species 0.000 description 2
- 241000244031 Toxocara Species 0.000 description 2
- 241000244030 Toxocara canis Species 0.000 description 2
- 150000001556 benzimidazoles Chemical class 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- KPZGRMZPZLOPBS-UHFFFAOYSA-N 1,3-dichloro-2,2-bis(chloromethyl)propane Chemical compound ClCC(CCl)(CCl)CCl KPZGRMZPZLOPBS-UHFFFAOYSA-N 0.000 description 1
- RYHBNJHYFVUHQT-UHFFFAOYSA-N 1,4-Dioxane Chemical compound C1COCCO1 RYHBNJHYFVUHQT-UHFFFAOYSA-N 0.000 description 1
- 241001147657 Ancylostoma Species 0.000 description 1
- 241000204727 Ascaridia Species 0.000 description 1
- 241000244186 Ascaris Species 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 241000242711 Fasciola hepatica Species 0.000 description 1
- 241001263042 Fasciola sp. Species 0.000 description 1
- 241001126309 Fasciolopsis Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 241000920462 Heterakis Species 0.000 description 1
- 241000282414 Homo sapiens Species 0.000 description 1
- 239000005909 Kieselgur Substances 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 241001480234 Paragonimus westermani Species 0.000 description 1
- 241000244187 Parascaris Species 0.000 description 1
- 208000030852 Parasitic disease Diseases 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 241000364057 Peoria Species 0.000 description 1
- 241000617809 Sinum Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 241000244159 Taenia saginata Species 0.000 description 1
- 241000607216 Toxascaris Species 0.000 description 1
- 229920001938 Vegetable gum Polymers 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000000440 bentonite Substances 0.000 description 1
- 229910000278 bentonite Inorganic materials 0.000 description 1
- SVPXDRXYRYOSEX-UHFFFAOYSA-N bentoquatam Chemical compound O.O=[Si]=O.O=[Al]O[Al]=O SVPXDRXYRYOSEX-UHFFFAOYSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 239000002775 capsule Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 235000013330 chicken meat Nutrition 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229960001760 dimethyl sulfoxide Drugs 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000006275 fascioliasis Diseases 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 210000001365 lymphatic vessel Anatomy 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- JYWIYHUXVMAGLG-UHFFFAOYSA-N oxyclozanide Chemical compound OC1=C(Cl)C=C(Cl)C=C1NC(=O)C1=C(O)C(Cl)=CC(Cl)=C1Cl JYWIYHUXVMAGLG-UHFFFAOYSA-N 0.000 description 1
- 206010033675 panniculitis Diseases 0.000 description 1
- 230000000590 parasiticidal effect Effects 0.000 description 1
- 239000002297 parasiticide Substances 0.000 description 1
- 238000007911 parenteral administration Methods 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 210000004304 subcutaneous tissue Anatomy 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP56025058A JPS57139012A (en) | 1981-02-23 | 1981-02-23 | Anthelmintic composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ199817A true NZ199817A (en) | 1984-12-14 |
Family
ID=12155318
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ199817A NZ199817A (en) | 1981-02-23 | 1982-02-23 | Anthelmintic composition consisting of two components |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4468390A (enExample) |
| EP (1) | EP0059074B1 (enExample) |
| JP (1) | JPS57139012A (enExample) |
| AU (1) | AU552403B2 (enExample) |
| DE (2) | DE10299008I2 (enExample) |
| GB (1) | GB2093695B (enExample) |
| IE (1) | IE52364B1 (enExample) |
| NL (1) | NL300082I1 (enExample) |
| NZ (1) | NZ199817A (enExample) |
| ZA (1) | ZA821135B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214367B1 (en) | 1996-06-05 | 2001-04-10 | Ashmont Holdings Limited | Injectable compositions |
| AU2003236405B2 (en) * | 1999-04-14 | 2007-10-25 | Merial Ltd | Anthelmintic Composition |
| US7638545B1 (en) | 1999-04-14 | 2009-12-29 | Merial Limited | Anthelmintic composition |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6426333B1 (en) * | 1996-09-19 | 2002-07-30 | Merial | Spot-on formulations for combating parasites |
| FR2753377B1 (fr) * | 1996-09-19 | 1999-09-24 | Rhone Merieux | Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides |
| MA19678A1 (fr) * | 1982-01-13 | 1983-10-01 | Ciba Geigy Ag | Agents anti-helmintiques. |
| DE3410348A1 (de) * | 1984-03-21 | 1985-10-03 | Helmut Dr. Bozen Schwienbacher | Verfahren zur bekaempfung von fischmykosen und mittel zur durchfuehrung des verfahrens |
| ES2054962T3 (es) * | 1986-01-25 | 1994-08-16 | Hoechst Ag | Agentes plaguicidas. |
| GB9024924D0 (en) * | 1990-11-16 | 1991-01-02 | Beecham Group Plc | Novel compositions |
| AU691990B2 (en) * | 1994-11-28 | 1998-05-28 | Virbac S.A. | Equine anthelmintic formulations |
| AUPM969994A0 (en) | 1994-11-28 | 1994-12-22 | Virbac S.A. | Equine anthelmintic formulations |
| DE19520275A1 (de) * | 1995-06-02 | 1996-12-05 | Bayer Ag | Endoparasitizide Mittel |
| FR2739778B1 (fr) * | 1995-10-13 | 1997-12-12 | Virbac Lab | Formulation topique destinee a traiter la maladie de la douve du foie chez l'animal |
| DE19654079A1 (de) | 1996-12-23 | 1998-06-25 | Bayer Ag | Endo-ekto-parasitizide Mittel |
| US6733767B2 (en) | 1998-03-19 | 2004-05-11 | Merck & Co., Inc. | Liquid polymeric compositions for controlled release of bioactive substances |
| US6893652B2 (en) | 2001-08-27 | 2005-05-17 | Wyeth | Endoparasiticidal gel composition |
| US7001889B2 (en) * | 2002-06-21 | 2006-02-21 | Merial Limited | Anthelmintic oral homogeneous veterinary pastes |
| US20060205681A1 (en) * | 2002-06-21 | 2006-09-14 | Maryam Moaddeb | Homogenous paste formulations |
| US20040077703A1 (en) * | 2002-10-02 | 2004-04-22 | Soll Mark D. | Nodulisporic acid derivative spot-on formulations for combating parasites |
| LT1610613T (lt) * | 2003-04-04 | 2017-03-27 | Merial, Inc. | Vietinio taikymo antihelmintinės veterinarinės kompozicijos |
| CN1894581B (zh) * | 2003-07-09 | 2012-02-01 | 生命技术公司 | 检测蛋白-蛋白相互作用的方法 |
| US7396819B2 (en) | 2003-08-08 | 2008-07-08 | Virbac Corporation | Anthelmintic formulations |
| US7671034B2 (en) | 2003-12-19 | 2010-03-02 | Merial Limited | Stabilized formulation of ivermectin feed premix with an extended shelf life |
| WO2005094210A2 (en) | 2004-03-12 | 2005-10-13 | The Hartz Mountain Corporation | Multi-action anthelmintic formulations |
| BRPI0509673A (pt) * | 2004-04-07 | 2007-10-09 | Intervet Int Bv | composição para o tratamento de parasitas, forma de dosagem farmacêutica, método para tratar um organismo, e, processos para introduzir pelo menos um aditivo em um organismo, para fabricar uma composição, para liberar um aditivo em um organismo, e, para conformar um produto macio mastigável |
| GB0508993D0 (en) * | 2005-05-03 | 2005-06-08 | Syngenta Participations Ag | Pesticidal compositions |
| US8362086B2 (en) | 2005-08-19 | 2013-01-29 | Merial Limited | Long acting injectable formulations |
| US20080027011A1 (en) * | 2005-12-20 | 2008-01-31 | Hassan Nached | Homogeneous paste and gel formulations |
| CN101511795B (zh) | 2006-07-05 | 2013-09-18 | 安万特农业公司 | 1-芳基-5-烷基吡唑衍生化合物、其制备方法和使用方法 |
| US7919522B2 (en) * | 2007-05-03 | 2011-04-05 | Merial Limited | Compositions comprising C-13 alkoxyether macrolide compounds and phenylpyrazole compounds |
| PT3088384T (pt) | 2007-05-15 | 2019-03-22 | Aventis Agriculture | Compostos de ariloazol-2-il-cianoetilamino, método de fabrico e seu método de utilização |
| BRPI0819849B8 (pt) | 2007-11-26 | 2021-05-25 | Merial Ltd | sistemas de solvente para formulações pour on para combater parasitas |
| RU2493825C2 (ru) | 2008-10-08 | 2013-09-27 | ВАЙЕТ ЭлЭлСи | Бензимидазольные антигельминтные композиции |
| AR074024A1 (es) | 2008-11-14 | 2010-12-15 | Merial Ltd | Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria |
| WO2010059529A2 (en) | 2008-11-19 | 2010-05-27 | Merial Limited | Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof |
| WO2010107791A2 (en) | 2009-03-17 | 2010-09-23 | Concert Pharmaceuticals, Inc. | Pyrazinoisoquinoline compounds |
| ES2546100T3 (es) | 2009-12-04 | 2015-09-18 | Merial, Inc. | Compuestos pesticidas bis-organosulfurados |
| PT3078664T (pt) | 2009-12-17 | 2019-05-31 | Boehringer Ingelheim Animal Health Usa Inc | Composições antiparasitárias de di-hidroazoles |
| UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
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Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4914624A (enExample) * | 1972-06-08 | 1974-02-08 | ||
| PH15982A (en) * | 1977-10-03 | 1983-05-18 | Merck & Co Inc | Selective hydrogenation producta of c-076 compounds and derivatives thereof |
| US4144352A (en) * | 1977-12-19 | 1979-03-13 | Merck & Co., Inc. | Milbemycin compounds as anthelmintic agents |
| US4203976A (en) * | 1978-08-02 | 1980-05-20 | Merck & Co., Inc. | Sugar derivatives of C-076 compounds |
| US4289760A (en) * | 1980-05-02 | 1981-09-15 | Merck & Co., Inc. | 23-Keto derivatives of C-076 compounds |
-
1981
- 1981-02-23 JP JP56025058A patent/JPS57139012A/ja active Granted
-
1982
- 1982-02-18 DE DE2002199008 patent/DE10299008I2/de active Active
- 1982-02-18 EP EP82300829A patent/EP0059074B1/en not_active Expired
- 1982-02-18 GB GB8204765A patent/GB2093695B/en not_active Expired
- 1982-02-18 DE DE8282300829T patent/DE3260921D1/de not_active Expired
- 1982-02-22 IE IE369/82A patent/IE52364B1/en active Protection Beyond IP Right Term
- 1982-02-22 ZA ZA821135A patent/ZA821135B/xx unknown
- 1982-02-22 US US06/350,641 patent/US4468390A/en not_active Expired - Lifetime
- 1982-02-23 NZ NZ199817A patent/NZ199817A/en unknown
- 1982-02-23 AU AU80711/82A patent/AU552403B2/en not_active Expired
-
2002
- 2002-02-13 NL NL300082C patent/NL300082I1/nl unknown
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6214367B1 (en) | 1996-06-05 | 2001-04-10 | Ashmont Holdings Limited | Injectable compositions |
| US6663879B2 (en) | 1996-06-05 | 2003-12-16 | Ashmont Holdings Limited | Injectable compositions |
| AU2003236405B2 (en) * | 1999-04-14 | 2007-10-25 | Merial Ltd | Anthelmintic Composition |
| US7638545B1 (en) | 1999-04-14 | 2009-12-29 | Merial Limited | Anthelmintic composition |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0125722B2 (enExample) | 1989-05-19 |
| ZA821135B (en) | 1983-02-23 |
| AU8071182A (en) | 1982-09-02 |
| IE52364B1 (en) | 1987-09-30 |
| US4468390A (en) | 1984-08-28 |
| EP0059074B1 (en) | 1984-10-10 |
| DE10299008I2 (de) | 2004-10-21 |
| EP0059074A1 (en) | 1982-09-01 |
| JPS57139012A (en) | 1982-08-27 |
| GB2093695A (en) | 1982-09-08 |
| AU552403B2 (en) | 1986-05-29 |
| GB2093695B (en) | 1984-03-28 |
| DE10299008I1 (de) | 2002-07-04 |
| NL300082I1 (nl) | 2002-04-02 |
| DE3260921D1 (en) | 1984-11-15 |
| IE820369L (en) | 1982-08-23 |
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