NZ195702A - 7-(3-(isopropyl or t-butyl)amino-2-hydroxypropoxy)-indolin-2,3-diones - Google Patents

7-(3-(isopropyl or t-butyl)amino-2-hydroxypropoxy)-indolin-2,3-diones

Info

Publication number
NZ195702A
NZ195702A NZ195702A NZ19570280A NZ195702A NZ 195702 A NZ195702 A NZ 195702A NZ 195702 A NZ195702 A NZ 195702A NZ 19570280 A NZ19570280 A NZ 19570280A NZ 195702 A NZ195702 A NZ 195702A
Authority
NZ
New Zealand
Prior art keywords
indoledione
pharmaceutically acceptable
acceptable acid
formula
addition salts
Prior art date
Application number
NZ195702A
Other languages
English (en)
Inventor
G A Fothergill
J M Osbond
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ195702A publication Critical patent/NZ195702A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32Oxygen atoms
    • C07D209/38Oxygen atoms in positions 2 and 3, e.g. isatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ195702A 1979-12-07 1980-12-01 7-(3-(isopropyl or t-butyl)amino-2-hydroxypropoxy)-indolin-2,3-diones NZ195702A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7942324 1979-12-07

Publications (1)

Publication Number Publication Date
NZ195702A true NZ195702A (en) 1984-09-28

Family

ID=10509706

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ195702A NZ195702A (en) 1979-12-07 1980-12-01 7-(3-(isopropyl or t-butyl)amino-2-hydroxypropoxy)-indolin-2,3-diones

Country Status (16)

Country Link
US (1) US4395559A (enExample)
EP (1) EP0030380A1 (enExample)
JP (1) JPS5695167A (enExample)
AR (1) AR226869A1 (enExample)
AU (1) AU6494680A (enExample)
DK (1) DK522180A (enExample)
ES (1) ES8205770A1 (enExample)
FI (1) FI803727L (enExample)
GR (1) GR72136B (enExample)
HU (1) HU180620B (enExample)
IL (1) IL61603A0 (enExample)
MC (1) MC1357A1 (enExample)
NO (1) NO803693L (enExample)
NZ (1) NZ195702A (enExample)
PT (1) PT72176B (enExample)
ZA (1) ZA807494B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4593106A (en) * 1984-06-04 1986-06-03 Smithkline Beckman Corporation 4-[2-(dialkylamino)ethyl]-7-hydroxyisatins
US4847863A (en) * 1985-10-03 1989-07-11 Watson Bruce W Expandable modular data modem
AR016384A1 (es) * 1997-07-30 2001-07-04 Smithkline Beecham Corp Inhibidores de caspasas, composiciones farmaceuticas que comprenden dichos inhibidores de caspasas y uso de los inhibidores de caspasas para prepararun medicamento util para el tratamiento de apoptosis y desordenes asociados con excesiva actividad de la convertosa il-1 beta.
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN101287411B (zh) 2005-04-28 2013-03-06 普罗秋斯生物医学公司 药物信息系统及其用途
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1778174A (en) * 1926-05-30 1930-10-14 Gen Aniline Works Inc Substituted isatins and process of preparing them
GB1069343A (en) * 1963-09-10 1967-05-17 Ici Ltd Propanolamine derivatives
CH472404A (de) * 1966-03-04 1969-05-15 Sandoz Ag Verfahren zur Herstellung neuer Indolderivate
SE379196B (enExample) * 1971-06-24 1975-09-29 Sandoz Ag
US4137331A (en) * 1974-06-19 1979-01-30 Sandoz Ltd. 3-Piperidino-2-hydroxypropoxy substituted-2-indolinones
US4212804A (en) * 1978-12-04 1980-07-15 Sandoz, Inc. Process for the preparation of optionally substituted 2,3-indolinediones

Also Published As

Publication number Publication date
PT72176B (en) 1982-07-05
FI803727A7 (fi) 1981-06-08
FI803727L (fi) 1981-06-08
PT72176A (en) 1981-01-01
MC1357A1 (fr) 1981-08-10
DK522180A (da) 1981-06-08
AR226869A1 (es) 1982-08-31
IL61603A0 (en) 1981-01-30
JPS5695167A (en) 1981-08-01
ES497530A0 (es) 1982-07-01
US4395559A (en) 1983-07-26
NO803693L (no) 1981-06-09
GR72136B (enExample) 1983-09-20
ES8205770A1 (es) 1982-07-01
HU180620B (en) 1983-03-28
AU6494680A (en) 1981-06-11
EP0030380A1 (de) 1981-06-17
ZA807494B (en) 1981-11-25

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