NZ187066A - 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones) - Google Patents

4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones)

Info

Publication number
NZ187066A
NZ187066A NZ187066A NZ18706678A NZ187066A NZ 187066 A NZ187066 A NZ 187066A NZ 187066 A NZ187066 A NZ 187066A NZ 18706678 A NZ18706678 A NZ 18706678A NZ 187066 A NZ187066 A NZ 187066A
Authority
NZ
New Zealand
Prior art keywords
benzimidazolidin
substitutedamino
thiones
hydroxypropoxy
ones
Prior art date
Application number
NZ187066A
Other languages
English (en)
Inventor
R E Markwell
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB18438/77A external-priority patent/GB1595316A/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NZ187066A publication Critical patent/NZ187066A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
NZ187066A 1977-05-03 1978-04-26 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones) NZ187066A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB18438/77A GB1595316A (en) 1977-05-03 1977-05-03 4-(3-amino-2-hydroxy-propoxy)-benzimidazole derivatives and pharmaceutical compositions containing them
GB4915677 1977-11-25
GB220878 1978-01-19

Publications (1)

Publication Number Publication Date
NZ187066A true NZ187066A (en) 1981-02-11

Family

ID=27254036

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ187066A NZ187066A (en) 1977-05-03 1978-04-26 4-(3-substitutedamino-2-hydroxypropoxy)-benzimidazolidin-2-(ones or thiones)

Country Status (18)

Country Link
JP (1) JPS53135979A (xx)
AR (2) AR220335A1 (xx)
AU (1) AU3569678A (xx)
DE (1) DE2819458A1 (xx)
DK (1) DK190378A (xx)
ES (1) ES469353A1 (xx)
FI (1) FI781349A (xx)
FR (1) FR2399414A1 (xx)
GR (1) GR73669B (xx)
IL (1) IL54591A0 (xx)
IT (1) IT1096276B (xx)
LU (1) LU79591A1 (xx)
MC (1) MC1192A1 (xx)
NL (1) NL7804794A (xx)
NO (1) NO781556L (xx)
NZ (1) NZ187066A (xx)
PT (1) PT67980A (xx)
SE (1) SE7805140L (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801980A1 (de) * 1978-01-18 1979-07-19 Boehringer Mannheim Gmbh 4-hydroxy-2-benzimidazolin-thion- derivate, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
EP0003758A1 (de) * 1978-02-09 1979-09-05 Ciba-Geigy Ag Verätherte Hydroxy-benzodiheterocyclen und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2905877A1 (de) * 1979-02-16 1980-08-28 Boehringer Mannheim Gmbh Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CH661501A5 (fr) * 1982-01-26 1987-07-31 Oreal Composes derivant du amino-3 propanol-2 utilisables pour la teinture des cheveux, leur procede de preparation, composition de teinture les contenant et procede de teinture de cheveux correspondant.
DE3839743A1 (de) * 1988-11-25 1990-05-31 Hoechst Ag Verfahren zur herstellung von benzimidazolonen
US9784726B2 (en) 2013-01-08 2017-10-10 Atrogi Ab Screening method, a kit, a method of treatment and a compound for use in a method of treatment
GB201714740D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714745D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714736D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB201714734D0 (en) 2017-09-13 2017-10-25 Atrogi Ab New compounds and uses
GB202205895D0 (en) 2022-04-22 2022-06-08 Atrogi Ab New medical uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1058822A (en) * 1963-07-30 1967-02-15 Ici Ltd 3-amino-2-hydroxypropoxy heterocyclic derivatives
CH559729A5 (xx) * 1970-10-23 1975-03-14 Hoechst Ag
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH624395A5 (xx) * 1976-01-08 1981-07-31 Ciba Geigy Ag

Also Published As

Publication number Publication date
FI781349A (fi) 1978-11-04
MC1192A1 (fr) 1979-02-23
SE7805140L (sv) 1978-11-04
IT1096276B (it) 1985-08-26
FR2399414A1 (fr) 1979-03-02
GR73669B (xx) 1984-03-28
AR219173A1 (es) 1980-07-31
DK190378A (da) 1978-11-04
PT67980B (xx) 1980-05-05
NO781556L (no) 1978-11-06
LU79591A1 (de) 1979-06-13
AU3569678A (en) 1979-11-08
IL54591A0 (en) 1978-07-31
PT67980A (en) 1978-06-01
IT7823000A0 (it) 1978-05-03
NL7804794A (nl) 1978-11-07
AR220335A1 (es) 1980-10-31
ES469353A1 (es) 1980-01-01
JPS53135979A (en) 1978-11-28
DE2819458A1 (de) 1978-11-16

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