NO995770L - Salts of aromatic sulfonic acids - Google Patents
Salts of aromatic sulfonic acidsInfo
- Publication number
- NO995770L NO995770L NO995770A NO995770A NO995770L NO 995770 L NO995770 L NO 995770L NO 995770 A NO995770 A NO 995770A NO 995770 A NO995770 A NO 995770A NO 995770 L NO995770 L NO 995770L
- Authority
- NO
- Norway
- Prior art keywords
- aromatic sulfonic
- salts
- sulfonic acids
- salt
- oxepino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Oppfinnelsen er et salt av det CNS-depressante trans-5-klor-2,3,3a,12b- tetrahydro-2-metyl-1H-dibenz[2,3:6,7]oksepino[4,5-c]pyrrol og et saltdannende middel, idet sistnevnte er en aromatisk sulfonsyre. Det beskrevne salt, fortrinnsvis benzylatet, har gunstige egenskaper. Således har det den nødvendige uløselig- het og krystallinitet til å være egnet for anvendelse i depot injeksjonspreparater.The invention is a salt of the CNS-depressant trans-5-chloro-2,3,3a, 12b-tetrahydro-2-methyl-1H-dibenz [2,3: 6,7] oxepino [4,5-c] pyrrole and a salt-forming agent, the latter being an aromatic sulfonic acid. The salt described, preferably the benzylate, has favorable properties. Thus, it has the necessary insolubility and crystallinity to be suitable for use in depot injection preparations.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP97201596 | 1997-05-26 | ||
PCT/EP1998/003022 WO1998054186A1 (en) | 1997-05-26 | 1998-05-19 | Salts of aromatic sulphonic acids |
Publications (2)
Publication Number | Publication Date |
---|---|
NO995770L true NO995770L (en) | 1999-11-25 |
NO995770D0 NO995770D0 (en) | 1999-11-25 |
Family
ID=8228372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO995770A NO995770D0 (en) | 1997-05-26 | 1999-11-25 | Salts of aromatic sulfonic acids |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0984968A1 (en) |
JP (1) | JP2001526702A (en) |
KR (1) | KR20010012985A (en) |
CN (1) | CN1257504A (en) |
AU (1) | AU7767598A (en) |
BR (1) | BR9809162A (en) |
CA (1) | CA2290070A1 (en) |
HU (1) | HUP0002106A3 (en) |
NO (1) | NO995770D0 (en) |
PL (1) | PL337027A1 (en) |
TR (1) | TR199902727T2 (en) |
WO (1) | WO1998054186A1 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5067998B2 (en) | 2001-10-30 | 2012-11-07 | ノバルティス アーゲー | Depot formulation of iloperidone and star polymer |
HRP20020440B1 (en) | 2002-05-21 | 2008-02-29 | GlaxoSmithKline istra�iva�ki centar Zagreb d.o.o. | 1-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof |
HRP20020452A2 (en) | 2002-05-23 | 2004-02-29 | Pliva D D | 1,2-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediates for preparation thereof |
GB0216416D0 (en) | 2002-07-15 | 2002-08-21 | Novartis Ag | Organic compounds |
EP1802301A1 (en) * | 2004-10-15 | 2007-07-04 | Pfizer Inc. | Treatment of bipolar disorders and associated symptoms |
JP5801295B2 (en) | 2009-06-24 | 2015-10-28 | メルク・シャープ・エンド・ドーム・ベー・フェー | Injectable formulation containing asenapine and method of treatment using the same |
ITMI20110734A1 (en) | 2011-05-02 | 2012-11-03 | Olon Spa | CRYSTALLINE ASENAPINE SALTS |
EP2524919A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids |
EP2524920A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Asenapine Hydrochloride Salt Forms |
EP2524921A1 (en) | 2011-05-17 | 2012-11-21 | Sandoz AG | Novel Crystalline Salts of Asenapine |
AU2017384526B2 (en) | 2016-12-20 | 2023-11-02 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
US11337932B2 (en) | 2016-12-20 | 2022-05-24 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene |
US11033512B2 (en) | 2017-06-26 | 2021-06-15 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer |
CN112704672A (en) | 2018-06-20 | 2021-04-27 | 罗曼治疗系统股份公司 | Transdermal therapeutic system comprising asenapine |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL7605526A (en) * | 1976-05-24 | 1977-11-28 | Akzo Nv | NEW TETRACYCLICAL DERIVATIVES. |
-
1998
- 1998-05-19 HU HU0002106A patent/HUP0002106A3/en unknown
- 1998-05-19 WO PCT/EP1998/003022 patent/WO1998054186A1/en not_active Application Discontinuation
- 1998-05-19 EP EP98925632A patent/EP0984968A1/en not_active Withdrawn
- 1998-05-19 KR KR1019997010957A patent/KR20010012985A/en not_active Application Discontinuation
- 1998-05-19 BR BR9809162-0A patent/BR9809162A/en not_active Application Discontinuation
- 1998-05-19 PL PL98337027A patent/PL337027A1/en unknown
- 1998-05-19 AU AU77675/98A patent/AU7767598A/en not_active Abandoned
- 1998-05-19 JP JP50020299A patent/JP2001526702A/en active Pending
- 1998-05-19 CA CA002290070A patent/CA2290070A1/en not_active Abandoned
- 1998-05-19 TR TR1999/02727T patent/TR199902727T2/en unknown
- 1998-05-19 CN CN98805420A patent/CN1257504A/en active Pending
-
1999
- 1999-11-25 NO NO995770A patent/NO995770D0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR9809162A (en) | 2000-08-01 |
AU7767598A (en) | 1998-12-30 |
HUP0002106A3 (en) | 2001-11-28 |
PL337027A1 (en) | 2000-07-31 |
JP2001526702A (en) | 2001-12-18 |
CN1257504A (en) | 2000-06-21 |
TR199902727T2 (en) | 2000-07-21 |
NO995770D0 (en) | 1999-11-25 |
HUP0002106A2 (en) | 2000-11-28 |
WO1998054186A1 (en) | 1998-12-03 |
EP0984968A1 (en) | 2000-03-15 |
CA2290070A1 (en) | 1998-12-03 |
KR20010012985A (en) | 2001-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |