NO994771L - Fremgangsmåte ved fremstilling av oligosakkarider - Google Patents

Fremgangsmåte ved fremstilling av oligosakkarider

Info

Publication number
NO994771L
NO994771L NO994771A NO994771A NO994771L NO 994771 L NO994771 L NO 994771L NO 994771 A NO994771 A NO 994771A NO 994771 A NO994771 A NO 994771A NO 994771 L NO994771 L NO 994771L
Authority
NO
Norway
Prior art keywords
oligosaccharides
preparation
crude
glycosyltransferase
synthesizing
Prior art date
Application number
NO994771A
Other languages
English (en)
Other versions
NO994771D0 (no
Inventor
Pedro A Prieto
Karen M Kleman-Leyer
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO994771L publication Critical patent/NO994771L/no
Publication of NO994771D0 publication Critical patent/NO994771D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Det er beskrevet en fremgangsmåte for å syntetisere. oligosakkarider. Fremgangsmåten involverer å sette en akseptorenhet i kontakt med urensede sukkernukleotider og/eller urenset glykosyltransferase for å syntetisere oligosakkarider.
NO994771A 1997-03-31 1999-09-30 FremgangsmÕte ved fremstilling av oligosakkarider NO994771D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/829,010 US5945314A (en) 1997-03-31 1997-03-31 Process for synthesizing oligosaccharides
PCT/US1998/006239 WO1998044145A1 (en) 1997-03-31 1998-03-30 A process for synthesizing oligosaccharides

Publications (2)

Publication Number Publication Date
NO994771L true NO994771L (no) 1999-09-30
NO994771D0 NO994771D0 (no) 1999-09-30

Family

ID=25253280

Family Applications (1)

Application Number Title Priority Date Filing Date
NO994771A NO994771D0 (no) 1997-03-31 1999-09-30 FremgangsmÕte ved fremstilling av oligosakkarider

Country Status (6)

Country Link
US (1) US5945314A (no)
EP (1) EP0972068A1 (no)
JP (1) JP2001518783A (no)
CA (1) CA2284731A1 (no)
NO (1) NO994771D0 (no)
WO (1) WO1998044145A1 (no)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
WO2000012747A1 (en) * 1998-08-31 2000-03-09 Kurt Nilsson Method for enzymatic synthesis of glycosides, disaccharides, and oligosaccharides
JP2002530087A (ja) * 1998-11-18 2002-09-17 ネオーズ テクノロジーズ， インコーポレイテッド オリゴ糖の安価な産生
FR2796082B1 (fr) * 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
US7449308B2 (en) * 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US8697394B2 (en) * 2000-06-28 2014-04-15 Glycofi, Inc. Production of modified glycoproteins having multiple antennary structures
US7598055B2 (en) * 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
DK1522590T3 (da) 2000-06-28 2009-12-21 Glycofi Inc Fremgangsmåde til fremstilling af modificerede glykoproteiner
US7863020B2 (en) * 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
US6596707B2 (en) 2001-05-24 2003-07-22 Abbott Laboratories Monovalent saccharides and uses thereof
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7399613B2 (en) * 2001-10-10 2008-07-15 Neose Technologies, Inc. Sialic acid nucleotide sugars
CN101724075B (zh) 2001-10-10 2014-04-30 诺和诺德公司 肽的重构和糖缀合
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
WO2004099231A2 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
US7696163B2 (en) 2001-10-10 2010-04-13 Novo Nordisk A/S Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7795210B2 (en) 2001-10-10 2010-09-14 Novo Nordisk A/S Protein remodeling methods and proteins/peptides produced by the methods
US7157277B2 (en) 2001-11-28 2007-01-02 Neose Technologies, Inc. Factor VIII remodeling and glycoconjugation of Factor VIII
US7179617B2 (en) * 2001-10-10 2007-02-20 Neose Technologies, Inc. Factor IX: remolding and glycoconjugation of Factor IX
US8008252B2 (en) * 2001-10-10 2011-08-30 Novo Nordisk A/S Factor VII: remodeling and glycoconjugation of Factor VII
MXPA04012496A (es) 2002-06-21 2005-09-12 Novo Nordisk Healthcare Ag Glicoformos del factor vii pegilados.
US20040077590A1 (en) * 2002-10-22 2004-04-22 Leach James L. Use of soluble monovalent oligosaccharides as inhibitors of HIV-1 fusion and replication
US20050085441A1 (en) * 2002-10-22 2005-04-21 Leach James L. Use of soluble monovalent oligosaccharides as inhibitors of HIV-1 fusion and replication
US7332299B2 (en) 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
CA2519092C (en) 2003-03-14 2014-08-05 Neose Technologies, Inc. Branched water-soluble polymers and their conjugates
US8791070B2 (en) 2003-04-09 2014-07-29 Novo Nordisk A/S Glycopegylated factor IX
EP1613261A4 (en) * 2003-04-09 2011-01-26 Novo Nordisk As INTRA-CELLULAR FORMATION OF PEPTIDE CONJUGATES
US7046712B2 (en) * 2003-05-02 2006-05-16 Jds Uniphase Corporation Laser resistant to internal ir-induced damage
AU2004240553A1 (en) 2003-05-09 2004-12-02 Neose Technologies, Inc. Compositions and methods for the preparation of human growth hormone glycosylation mutants
US9005625B2 (en) 2003-07-25 2015-04-14 Novo Nordisk A/S Antibody toxin conjugates
EP1669461A4 (en) * 2003-09-26 2011-06-29 Yamasa Corp PROCESS FOR PREPARING CMP-N-ACETYLNEURAMIC ACID
US7842661B2 (en) 2003-11-24 2010-11-30 Novo Nordisk A/S Glycopegylated erythropoietin formulations
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
US8633157B2 (en) 2003-11-24 2014-01-21 Novo Nordisk A/S Glycopegylated erythropoietin
US20080318850A1 (en) * 2003-12-03 2008-12-25 Neose Technologies, Inc. Glycopegylated Factor Ix
US20060040856A1 (en) * 2003-12-03 2006-02-23 Neose Technologies, Inc. Glycopegylated factor IX
US7956032B2 (en) * 2003-12-03 2011-06-07 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
NZ548123A (en) 2004-01-08 2010-05-28 Novo Nordisk As O-linked glycosylation of peptides
EP1771066A2 (en) 2004-07-13 2007-04-11 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 glp-1
EP1799249A2 (en) 2004-09-10 2007-06-27 Neose Technologies, Inc. Glycopegylated interferon alpha
WO2006035057A1 (en) * 2004-09-29 2006-04-06 Novo Nordisk Health Care Ag Modified proteins
US20080176790A1 (en) 2004-10-29 2008-07-24 Defrees Shawn Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf)
US9029331B2 (en) 2005-01-10 2015-05-12 Novo Nordisk A/S Glycopegylated granulocyte colony stimulating factor
EP1866427A4 (en) * 2005-03-30 2010-09-01 Novo Nordisk As MANUFACTURING PROCESS FOR THE PRODUCTION OF CULTIVE PEPTIDES IN CELL LINES OF INSECTS
EP1871795A4 (en) 2005-04-08 2010-03-31 Biogenerix Ag COMPOSITIONS AND METHOD FOR PRODUCING GLYCOSYLATION MUTANTS OF A PROTEASE-RESISTANT HUMAN GROWTH HORMONE
JP5216580B2 (ja) * 2005-05-25 2013-06-19 ノヴォ ノルディスク アー／エス グリコペグ化第ｉｘ因子
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
EP1937719A4 (en) * 2005-08-19 2010-11-24 Novo Nordisk As GLYCOPEGYLATED FACTOR VII AND FACTOR VIIA
WO2007056191A2 (en) 2005-11-03 2007-05-18 Neose Technologies, Inc. Nucleotide sugar purification using membranes
US7605255B2 (en) 2006-06-29 2009-10-20 Alberta Research Council Inc. Non-animal based lactose
US20080242607A1 (en) * 2006-07-21 2008-10-02 Neose Technologies, Inc. Glycosylation of peptides via o-linked glycosylation sequences
US20100075375A1 (en) 2006-10-03 2010-03-25 Novo Nordisk A/S Methods for the purification of polypeptide conjugates
US20080207487A1 (en) * 2006-11-02 2008-08-28 Neose Technologies, Inc. Manufacturing process for the production of polypeptides expressed in insect cell-lines
DK2144923T3 (da) 2007-04-03 2013-05-13 Biogenerix Ag Behandlingsfremgangsmåder under anvendelse af glycopegyleret g-csf
WO2008154639A2 (en) 2007-06-12 2008-12-18 Neose Technologies, Inc. Improved process for the production of nucleotide sugars
US8207112B2 (en) 2007-08-29 2012-06-26 Biogenerix Ag Liquid formulation of G-CSF conjugate
CA2715465C (en) 2008-02-27 2017-03-21 Novo Nordisk A/S Conjugated factor viii molecules
IT1392456B1 (it) 2008-12-18 2012-03-09 Inalco Spa Processo per la sintesi di di- o oligosaccaridi l-fucosilati e loro nuovi intermedi 2,3,4-tribenzil-fucosil-derivati.
EP2769726B1 (en) * 2013-02-21 2018-10-31 Jennewein Biotechnologie GmbH Synthetic or recombinant fucosylated Oligosaccarides for use in the treatment of infections
PL2896628T3 (pl) 2014-01-20 2019-03-29 Jennewein Biotechnologie Gmbh Sposób wydajnego oczyszczania obojętnych oligosacharydów ludzkiego mleka (HMO) z fermentacji mikrobiologicznej
KR20160036248A (ko) * 2014-09-25 2016-04-04 서울대학교산학협력단 고함량의 올리고당을 포함하는 건강음료의 제조방법 및 이에 의해 제조된 건강음료
US11248217B2 (en) 2018-08-20 2022-02-15 Rutgers, The State University Of New Jersey Engineered carbohydrate-active enzymes for glycan polymers synthesis
EP3670662A1 (en) 2018-12-20 2020-06-24 Basf Se Enzymatic hexosaminidation of lactose

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4219571A (en) * 1978-06-15 1980-08-26 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Process for producing a sweetener
US5541083A (en) * 1989-10-24 1996-07-30 The Regents Of The University Of California Method for producing secretable glycosyltransferases and other golgi processing enzymes
WO1991016449A1 (en) * 1990-04-16 1991-10-31 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
US5583042A (en) * 1990-04-16 1996-12-10 Neose Pharmaceuticals, Inc. Apparatus for the synthesis of saccharide compositions
JPH08503373A (ja) * 1992-11-27 1996-04-16 チバ−ガイギー アクチェンゲゼルシャフト グリコシルトランスフェラーゼ活性を有するタンパク質
US5426178A (en) * 1993-03-31 1995-06-20 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Synthesis of anti-inflammatory compounds, and novel trisaccharides useful in the synthesis of anti-inflammatory compounds
WO1995002683A1 (en) * 1993-07-15 1995-01-26 Neose Pharmaceuticals Method of synthesizing saccharide compositions
US5516665A (en) * 1993-09-13 1996-05-14 The Scripps Research Institute N-acetylgalactosaminyl or N-acetylglucosaminyl transfer using N-acetylglucosaminyl-1-phosphate or N-acetylgalactosaminyl-1-phosphate as precursor and glycosyl-nucleotide regeneration
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US5728554A (en) * 1995-04-11 1998-03-17 Cytel Corporation Enzymatic synthesis of glycosidic linkages

Also Published As

Publication number Publication date
JP2001518783A (ja) 2001-10-16
US5945314A (en) 1999-08-31
CA2284731A1 (en) 1998-10-08
WO1998044145A1 (en) 1998-10-08
EP0972068A1 (en) 2000-01-19
NO994771D0 (no) 1999-09-30

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