NO993935D0 - Behandling av infarkter ved inhibering av NF-<Kappa>B - Google Patents

Behandling av infarkter ved inhibering av NF-<Kappa>B

Info

Publication number
NO993935D0
NO993935D0 NO993935A NO993935A NO993935D0 NO 993935 D0 NO993935 D0 NO 993935D0 NO 993935 A NO993935 A NO 993935A NO 993935 A NO993935 A NO 993935A NO 993935 D0 NO993935 D0 NO 993935D0
Authority
NO
Norway
Prior art keywords
infarcts
kappa
inhibiting
treatment
ubiquitin
Prior art date
Application number
NO993935A
Other languages
English (en)
Other versions
NO321203B1 (no
NO993935L (no
Inventor
Stephen Brand
Alfred L Goldberg
Louis Plamondon
Francois Soucy
Original Assignee
Proscript Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proscript Inc filed Critical Proscript Inc
Publication of NO993935D0 publication Critical patent/NO993935D0/no
Publication of NO993935L publication Critical patent/NO993935L/no
Publication of NO321203B1 publication Critical patent/NO321203B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Insulating Materials (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Artificial Filaments (AREA)
  • Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
  • Transplanting Machines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19993935A 1997-02-15 1999-08-16 Anvendelse av NF-<Kappa>B-aktiveringsinhibitor for fremstilling av et medikament for behandling av infarkter. NO321203B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80193697A 1997-02-15 1997-02-15
US98833997A 1997-12-03 1997-12-03
PCT/US1998/003077 WO1998035691A1 (en) 1997-02-15 1998-02-17 Treatment of infarcts through inhibition of nf-kappab

Publications (3)

Publication Number Publication Date
NO993935D0 true NO993935D0 (no) 1999-08-16
NO993935L NO993935L (no) 1999-10-04
NO321203B1 NO321203B1 (no) 2006-04-03

Family

ID=27122399

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19993935A NO321203B1 (no) 1997-02-15 1999-08-16 Anvendelse av NF-<Kappa>B-aktiveringsinhibitor for fremstilling av et medikament for behandling av infarkter.

Country Status (15)

Country Link
US (3) US6271199B2 (no)
EP (1) EP0979096B1 (no)
JP (1) JP2001511814A (no)
CN (1) CN1159061C (no)
AT (1) ATE240113T1 (no)
AU (1) AU741802B2 (no)
CA (1) CA2281224A1 (no)
DE (1) DE69814618T2 (no)
ES (1) ES2196547T3 (no)
HK (1) HK1025266A1 (no)
IL (1) IL131410A0 (no)
NO (1) NO321203B1 (no)
NZ (1) NZ337364A (no)
PT (1) PT979096E (no)
WO (1) WO1998035691A1 (no)

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US6921751B1 (en) 1998-05-20 2005-07-26 Erasmus Universiteit Rotterdam Immunoregulator
US20030220258A1 (en) * 2001-12-21 2003-11-27 Robbert Benner Treatment of ischemic events
US6844315B2 (en) * 1998-05-20 2005-01-18 Erasmus Universiteit Rotterdam Immunoregulator
US20090042807A1 (en) * 1998-05-20 2009-02-12 Nisar Ahmed Khan Oligopeptide treatment of ischemia reperfusion injury
EP1223948A2 (en) * 1999-09-13 2002-07-24 CHARLOTTE-MECKLENBURG HOSPITAL doing business as Carolinas Medical Center Method of inhibiting nf-kappa-b with heparin, for treating cardiovascular diseases and inflammations
US7358330B2 (en) 2001-03-29 2008-04-15 Biotempt B.V. Immunoregulatory compositions
USRE43279E1 (en) 2000-03-29 2012-03-27 Biotemp B.V. Compositions capable of reducing elevated blood urea concentration
US7576174B2 (en) 2000-03-29 2009-08-18 Biotempt B.V. Compositions capable of reducing elevated blood urea concentration
EP1300418A1 (en) 2001-10-04 2003-04-09 Erasmus Universiteit Rotterdam Gene regulation by oligopeptides
US6713459B1 (en) * 2000-04-28 2004-03-30 East Tennessee State University Methods for the prophylactic and therapeutic treatment of cardiac tissue damage
WO2002047610A2 (en) * 2000-11-16 2002-06-20 The Regents Of The University Of California Marine actinomycete taxon for drug and fermentation product dicovery
DK1355910T3 (da) 2001-01-25 2011-06-27 Us Of America Represented By The Secretary Dept Of Health And Human Services Formulering af borsyreforbindelser
DE60218153T2 (de) 2001-05-21 2007-06-28 Alcon Inc. Verwendung von proteasom-inhibitoren zur behandlung des trockenen auges
US7112588B2 (en) 2001-05-21 2006-09-26 Alcon, Inc. Use of proteasome inhibitors to treat dry eye disorders
DK1448205T3 (da) * 2001-10-05 2011-12-12 Zalicus Inc Kombinationer til behandling af immunoinflammatoriske sygdomme
JP4511183B2 (ja) * 2001-12-10 2010-07-28 デュ，ヤンシェン 神経変性疾患および心臓血管疾患の治療
US20080318871A1 (en) * 2001-12-21 2008-12-25 Khan Nisar A Treatment of neurological disorders
US7501391B2 (en) 2001-12-21 2009-03-10 Biotempt B.V. Treatment of transplant survival
US20080242837A1 (en) * 2001-12-21 2008-10-02 Khan Nisar A Peptide compositions
US7786084B2 (en) * 2001-12-21 2010-08-31 Biotempt B.V. Treatment of burns
US7176232B2 (en) 2002-06-24 2007-02-13 The Regents Of The University Of California Salinosporamides and methods for use thereof
US7517529B2 (en) * 2003-04-08 2009-04-14 Biotempt B.V. Treatment of type I diabetes
US20050004164A1 (en) * 2003-04-30 2005-01-06 Caggiano Thomas J. 2-Cyanopropanoic acid amide and ester derivatives and methods of their use
ZA200600473B (en) 2003-06-20 2007-04-25 Univ California Salinosporamides and methods for use thereof
DE602004031614D1 (de) 2003-06-20 2011-04-14 Nereus Pharmaceuticals Inc Verwendung von (3.2.0) heterocyclischen verbindungen und ihren analoga zur behandlung von krebs
WO2005023187A2 (en) * 2003-08-28 2005-03-17 Kem David C Inhibitor of cardiac tachyarrhythmias
US20090227505A1 (en) * 2004-01-07 2009-09-10 Biotempt B.V. Methods and uses for protein breakdown products
SE0400399D0 (sv) * 2004-02-20 2004-02-20 Index Pharmaceuticals Ab Methods and compositions for the treatment or prevention of secondary ischemic injury
US7579371B2 (en) 2004-04-30 2009-08-25 Nereus Pharmaceuticals, Inc. Methods of using [3.2.0] heterocyclic compounds and analogs thereof
BRPI0509824A (pt) * 2004-04-30 2007-10-09 Nereus Pharmaceuticals Inc compostos heterocìclicos [3.2.0] e métodos de uso dos mesmos
US7425580B2 (en) * 2004-05-19 2008-09-16 Wyeth (Diaryl-methyl)-malononitriles and their use as estrogen receptor ligands
EP1771194A2 (en) * 2004-07-07 2007-04-11 Biodevelops Pharma Entwicklung GmbH Use of a deubiquitinating compound for enhancing the expression of membrane proteins on the cell surface
US20060008454A1 (en) * 2004-07-07 2006-01-12 Dr. Helmut Brunar Use of a compound for enhancing the expression of membrane proteins on the cell surface
CA2578202C (en) * 2004-08-30 2013-12-17 Toray Industries, Inc. Fractionation apparatus
WO2006062732A2 (en) * 2004-11-19 2006-06-15 Synta Pharmaceuticals Corp. Compounds acting at the centrosome
CN103230394B (zh) * 2004-12-03 2016-04-20 达纳-法伯癌症研究公司 治疗肿瘤性疾病的化合物及其用途
KR20080033331A (ko) * 2005-07-05 2008-04-16 바이오템프트, 비.브이. 종양 치료제
WO2007002972A2 (en) * 2005-07-06 2007-01-11 Biodevelops Pharma Entwicklung Gmbh Use of a compound for enhancing the expression of membrane proteins on the cell surface
CA2614959A1 (en) * 2005-07-14 2007-01-25 Myogen, Inc. Use of inhibitors of the ubiquitin proteasome pathway for increasing contractility of the heart
US7691896B2 (en) * 2005-08-10 2010-04-06 President And Fellows Of Harvard College Analogs of salinosporamide A
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ES2293834B1 (es) * 2006-07-20 2009-02-16 Consejo Superior Investig. Cientificas Compuesto con actividad inhibidora de las interacciones ubc13-uev, composiciones farmaceuticas que lo comprenden y sus aplicaciones terapeuticas.
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DK2120991T3 (da) * 2007-02-12 2014-04-28 Biotempt Bv Behandling af traumatisk blødning med korte oligopeptider
WO2008137780A2 (en) * 2007-05-04 2008-11-13 Nereus Pharmaceuticals, Inc. Use of [3.2.0] heterocyclic compounds and analogs thereof for treating infectious diseases
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US8394816B2 (en) 2007-12-07 2013-03-12 Irene Ghobrial Methods of using [3.2.0] heterocyclic compounds and analogs thereof in treating Waldenstrom's Macroglobulinemia
EP2276765A4 (en) 2008-05-12 2011-10-19 Nereus Pharmaceuticals Inc SALINOSPORAMIDE DERIVATIVES AS PROTEASOMAL HEMMER
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EP2305285A1 (en) 2009-09-29 2011-04-06 Julius-Maximilians-Universität Würzburg Means and methods for treating ischemic conditions
EP2527434B1 (en) 2010-01-22 2017-08-09 Japan Science and Technology Agency Probe reagent for measurement of proteolytic activity
KR20130036228A (ko) 2010-03-31 2013-04-11 밀레니엄 파머슈티컬스 인코퍼레이티드 1-아미노-2-사이클로프로필에틸보론산의 유도체
HUE053247T2 (hu) 2012-05-09 2021-06-28 Cantex Pharmaceuticals Inc Mieloszuppresszió kezelése
US10023611B2 (en) 2013-04-16 2018-07-17 Cipla Limited Process for the preparation of bortezomib mannitol ester
WO2015117136A1 (en) 2014-02-03 2015-08-06 Ohio State Innovation Foundation Boronic acid esters and pharmaceutical formulations thereof
WO2015179443A1 (en) 2014-05-20 2015-11-26 Millennium Pharmaceuticals. Inc. Boron-containing proteasome inhibitors for use after primary cancer therapy
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Also Published As

Publication number Publication date
CN1250376A (zh) 2000-04-12
US20010053760A1 (en) 2001-12-20
CA2281224A1 (en) 1998-08-20
US20010002391A1 (en) 2001-05-31
NO321203B1 (no) 2006-04-03
WO1998035691A1 (en) 1998-08-20
CN1159061C (zh) 2004-07-28
NZ337364A (en) 2001-06-29
US6271199B2 (en) 2001-08-07
IL131410A0 (en) 2001-01-28
DE69814618D1 (de) 2003-06-18
AU6171998A (en) 1998-09-08
AU741802B2 (en) 2001-12-13
JP2001511814A (ja) 2001-08-14
ATE240113T1 (de) 2003-05-15
ES2196547T3 (es) 2003-12-16
EP0979096A1 (en) 2000-02-16
HK1025266A1 (en) 2000-11-10
DE69814618T2 (de) 2004-03-25
PT979096E (pt) 2003-09-30
US20030069189A1 (en) 2003-04-10
EP0979096B1 (en) 2003-05-14
NO993935L (no) 1999-10-04

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