NO983451L - Procedure for inhibiting colon tumors - Google Patents

Procedure for inhibiting colon tumors

Info

Publication number
NO983451L
NO983451L NO983451A NO983451A NO983451L NO 983451 L NO983451 L NO 983451L NO 983451 A NO983451 A NO 983451A NO 983451 A NO983451 A NO 983451A NO 983451 L NO983451 L NO 983451L
Authority
NO
Norway
Prior art keywords
procedure
inhibiting colon
colon tumors
inhibiting
rog
Prior art date
Application number
NO983451A
Other languages
Norwegian (no)
Other versions
NO983451D0 (en
Inventor
Maria L Brandi
Francesco Tonelli
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603150.5A external-priority patent/GB9603150D0/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO983451L publication Critical patent/NO983451L/en
Publication of NO983451D0 publication Critical patent/NO983451D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Fremgangsmåte for hemming av coloncancer omfatter administrering til et pattedyr som har behov for dette av en effektiv mengde av en forbindelse som har formel (I),. der Rog Ruavhengig av hverandre er hydrogen, -CH, (a), eller (b), hvori Ar eventuelt er substituert fenyl; RJ blir valgt fra gruppen bestående av pyrrolidin, heksametylenimin og piperidin; eller et farmasøytisk akseptabelt salt eller solvat derav.A method of inhibiting colon cancer comprises administering to a mammal in need thereof an effective amount of a compound of formula (I). wherein Rog Ru is independently hydrogen, -CH, (a), or (b), wherein Ar is optionally substituted phenyl; RJ is selected from the group consisting of pyrrolidine, hexamethyleneimine and piperidine; or a pharmaceutically acceptable salt or solvate thereof.

NO983451A 1996-01-29 1998-07-27 Procedure for inhibiting colon tumors NO983451D0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1077296P 1996-01-29 1996-01-29
GBGB9603150.5A GB9603150D0 (en) 1996-02-15 1996-02-15 Methods of inhibiting colon tumors
PCT/US1997/002286 WO1997026877A1 (en) 1996-01-29 1997-01-27 Methods of inhibiting colon tumors

Publications (2)

Publication Number Publication Date
NO983451L true NO983451L (en) 1998-07-27
NO983451D0 NO983451D0 (en) 1998-07-27

Family

ID=26308709

Family Applications (1)

Application Number Title Priority Date Filing Date
NO983451A NO983451D0 (en) 1996-01-29 1998-07-27 Procedure for inhibiting colon tumors

Country Status (19)

Country Link
EP (1) EP0921799A4 (en)
JP (1) JP2000503994A (en)
KR (1) KR19990082054A (en)
CN (1) CN1209745A (en)
AR (1) AR010978A1 (en)
AU (1) AU707892B2 (en)
BR (1) BR9700778A (en)
CO (1) CO4761062A1 (en)
CZ (1) CZ235498A3 (en)
EA (1) EA001104B1 (en)
ID (1) ID15917A (en)
IL (1) IL125521A (en)
MX (1) MX9806036A (en)
NO (1) NO983451D0 (en)
NZ (1) NZ331105A (en)
PL (1) PL328147A1 (en)
TW (1) TW446560B (en)
WO (1) WO1997026877A1 (en)
YU (1) YU2397A (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
IL111287A0 (en) * 1993-10-15 1994-12-29 Lilly Co Eli Methods for treating resistant neoplasms
US5574047A (en) * 1993-12-21 1996-11-12 Eli Lilly And Company Methods of inhibiting imperfect tissue repair

Also Published As

Publication number Publication date
MX9806036A (en) 1998-11-29
YU2397A (en) 1999-11-22
KR19990082054A (en) 1999-11-15
EP0921799A4 (en) 2002-03-13
EP0921799A1 (en) 1999-06-16
CO4761062A1 (en) 1999-04-27
AR010978A1 (en) 2000-08-02
CN1209745A (en) 1999-03-03
AU2123997A (en) 1997-08-20
JP2000503994A (en) 2000-04-04
BR9700778A (en) 1998-10-06
PL328147A1 (en) 1999-01-18
IL125521A0 (en) 1999-03-12
IL125521A (en) 2001-11-25
NO983451D0 (en) 1998-07-27
WO1997026877A1 (en) 1997-07-31
TW446560B (en) 2001-07-21
AU707892B2 (en) 1999-07-22
ID15917A (en) 1997-08-21
EA199800677A1 (en) 1999-02-25
NZ331105A (en) 2000-06-23
EA001104B1 (en) 2000-10-30
CZ235498A3 (en) 1999-02-17

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application