CO4761062A1 - PROCEDURES TO INHIBIT COLUMAN TUMORS - Google Patents

PROCEDURES TO INHIBIT COLUMAN TUMORS

Info

Publication number
CO4761062A1
CO4761062A1 CO97003856A CO97003856A CO4761062A1 CO 4761062 A1 CO4761062 A1 CO 4761062A1 CO 97003856 A CO97003856 A CO 97003856A CO 97003856 A CO97003856 A CO 97003856A CO 4761062 A1 CO4761062 A1 CO 4761062A1
Authority
CO
Colombia
Prior art keywords
columan
tumors
inhibit
procedures
hexamethyleneimino
Prior art date
Application number
CO97003856A
Other languages
Spanish (es)
Inventor
Maria Luisa Brandy
Francesco Tonelli
Original Assignee
Eli Lilly And Cvompany
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603150.5A external-priority patent/GB9603150D0/en
Application filed by Eli Lilly And Cvompany filed Critical Eli Lilly And Cvompany
Publication of CO4761062A1 publication Critical patent/CO4761062A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Un medicamento que contiene un compuesto que tiene la fórmula en la que R1 y R3 son independientemente hidrógeno,en el que Ar es feniloopcionalmente sustituido;R2 se selecciona entre el grupo compuesto por pirrolidino, hexametilenimino y piperidino; o una de sus sales o solvatos farmacéuticamente aceptables; en la preparación de un medicamento útil para inhibir cáncer de colon en un mamífero.A medicament containing a compound having the formula in which R1 and R3 are independently hydrogen, in which Ar is phenyl optionally substituted, R2 is selected from the group consisting of pyrrolidino, hexamethyleneimino and piperidino; or one of its pharmaceutically acceptable salts or solvates; in the preparation of a drug useful for inhibiting colon cancer in a mammal.

CO97003856A 1996-01-29 1997-01-28 PROCEDURES TO INHIBIT COLUMAN TUMORS CO4761062A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1077296P 1996-01-29 1996-01-29
GBGB9603150.5A GB9603150D0 (en) 1996-02-15 1996-02-15 Methods of inhibiting colon tumors

Publications (1)

Publication Number Publication Date
CO4761062A1 true CO4761062A1 (en) 1999-04-27

Family

ID=26308709

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97003856A CO4761062A1 (en) 1996-01-29 1997-01-28 PROCEDURES TO INHIBIT COLUMAN TUMORS

Country Status (19)

Country Link
EP (1) EP0921799A4 (en)
JP (1) JP2000503994A (en)
KR (1) KR19990082054A (en)
CN (1) CN1209745A (en)
AR (1) AR010978A1 (en)
AU (1) AU707892B2 (en)
BR (1) BR9700778A (en)
CO (1) CO4761062A1 (en)
CZ (1) CZ235498A3 (en)
EA (1) EA001104B1 (en)
ID (1) ID15917A (en)
IL (1) IL125521A (en)
MX (1) MX9806036A (en)
NO (1) NO983451L (en)
NZ (1) NZ331105A (en)
PL (1) PL328147A1 (en)
TW (1) TW446560B (en)
WO (1) WO1997026877A1 (en)
YU (1) YU2397A (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW366342B (en) * 1992-07-28 1999-08-11 Lilly Co Eli The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss
CZ253694A3 (en) * 1993-10-15 1995-05-17 Lilly Co Eli Pharmaceutical preparation for treating resistant neoplasms
US5574047A (en) * 1993-12-21 1996-11-12 Eli Lilly And Company Methods of inhibiting imperfect tissue repair

Also Published As

Publication number Publication date
AU707892B2 (en) 1999-07-22
MX9806036A (en) 1998-11-29
IL125521A0 (en) 1999-03-12
AR010978A1 (en) 2000-08-02
YU2397A (en) 1999-11-22
BR9700778A (en) 1998-10-06
EA199800677A1 (en) 1999-02-25
IL125521A (en) 2001-11-25
JP2000503994A (en) 2000-04-04
EP0921799A1 (en) 1999-06-16
WO1997026877A1 (en) 1997-07-31
PL328147A1 (en) 1999-01-18
ID15917A (en) 1997-08-21
CN1209745A (en) 1999-03-03
NO983451D0 (en) 1998-07-27
KR19990082054A (en) 1999-11-15
CZ235498A3 (en) 1999-02-17
AU2123997A (en) 1997-08-20
NZ331105A (en) 2000-06-23
NO983451L (en) 1998-07-27
TW446560B (en) 2001-07-21
EA001104B1 (en) 2000-10-30
EP0921799A4 (en) 2002-03-13

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