NO965302L - Alfa-cykloalkyl, aryl og aralkylsubstituerte polyjodinerte aroyloksyforbindelser - Google Patents

Alfa-cykloalkyl, aryl og aralkylsubstituerte polyjodinerte aroyloksyforbindelser

Info

Publication number
NO965302L
NO965302L NO965302A NO965302A NO965302L NO 965302 L NO965302 L NO 965302L NO 965302 A NO965302 A NO 965302A NO 965302 A NO965302 A NO 965302A NO 965302 L NO965302 L NO 965302L
Authority
NO
Norway
Prior art keywords
cycloalkyl
aryl
aralkyl
compounds
polyiodinated
Prior art date
Application number
NO965302A
Other languages
English (en)
Other versions
NO965302D0 (no
Inventor
Edward R Bacon
Carl R Illig
Irennegbe K Osifo
Xin Peng
John L Toner
Original Assignee
Nanosystems Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanosystems Llc filed Critical Nanosystems Llc
Publication of NO965302L publication Critical patent/NO965302L/no
Publication of NO965302D0 publication Critical patent/NO965302D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/53—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/54—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/88—Carboxylic acid amides having nitrogen atoms of carboxamide groups bound to an acyclic carbon atom and to a carbon atom of a six-membered aromatic ring wherein at least one ortho-hydrogen atom has been replaced
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Forbindelser med struktur (I) hvor m er l, 2, 3 eller 4; z-(-COO-4-m er resten av en polyjodinert aromatisk mono- eller polysyre; R1 er H, alkyl, fluoralkyl, cykloalkyl, aryl, aralkyl, alkoksyalkyl eller acet- amidoalkyl; n er et tall fra O til 20; R2 er cykloalkyl eller aryl; og R3, R4 og R5 er uavhengig H, alkyl, fluoralkyl, cykloalkyl, aryl, aralkyl, halogen, hydroksy, acylamino, acetamidoalkyl, cyano, sulfonyl, karboksamido eller sulfonamldo og er nyttig som røntgenkontråstmidler i medisinske diagnostiske røntgenbildedannende sammensetninger og fremgangsmåter.
NO965302A 1994-06-24 1996-12-11 Alfa-cykloalkyl, aryl og aralkylsubstituerte polyjodinerte aroyloksyforbindelser NO965302D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26560394A 1994-06-24 1994-06-24
PCT/US1995/007421 WO1996000211A1 (en) 1994-06-24 1995-06-09 Alpha-(cycloalkyl, aryl and aralkyl)substituted polyiodinated aroyloxy compounds

Publications (2)

Publication Number Publication Date
NO965302L true NO965302L (no) 1996-12-11
NO965302D0 NO965302D0 (no) 1996-12-11

Family

ID=23011132

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965302A NO965302D0 (no) 1994-06-24 1996-12-11 Alfa-cykloalkyl, aryl og aralkylsubstituerte polyjodinerte aroyloksyforbindelser

Country Status (8)

Country Link
EP (1) EP0767779A1 (no)
JP (1) JPH10502084A (no)
AU (1) AU2703595A (no)
CA (1) CA2191984A1 (no)
FI (1) FI965096A (no)
IL (1) IL114306A0 (no)
NO (1) NO965302D0 (no)
WO (1) WO1996000211A1 (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030152519A1 (en) * 2001-11-07 2003-08-14 Reinhard Koenig Methods for vascular imaging using nanoparticulate contrast agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL239757A (no) * 1958-06-03
US3144479A (en) * 1958-08-07 1964-08-11 Chemie Linz Ag New iodine-containing benzoic acid esters
US5322679A (en) * 1992-12-16 1994-06-21 Sterling Winthrop Inc. Iodinated aroyloxy esters

Also Published As

Publication number Publication date
JPH10502084A (ja) 1998-02-24
FI965096A0 (fi) 1996-12-18
FI965096A (fi) 1996-12-18
AU2703595A (en) 1996-01-19
EP0767779A1 (en) 1997-04-16
WO1996000211A1 (en) 1996-01-04
CA2191984A1 (en) 1996-01-04
IL114306A0 (en) 1995-10-31
NO965302D0 (no) 1996-12-11

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