NO963331D0 - 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister - Google Patents

5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister

Info

Publication number
NO963331D0
NO963331D0 NO963331A NO963331A NO963331D0 NO 963331 D0 NO963331 D0 NO 963331D0 NO 963331 A NO963331 A NO 963331A NO 963331 A NO963331 A NO 963331A NO 963331 D0 NO963331 D0 NO 963331D0
Authority
NO
Norway
Prior art keywords
antagonists
receptor site
benzodiazepine receptor
site agonists
heteroarylindole
Prior art date
Application number
NO963331A
Other languages
English (en)
Other versions
NO963331L (no
Inventor
John E Macor
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO963331D0 publication Critical patent/NO963331D0/no
Publication of NO963331L publication Critical patent/NO963331L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO963331A 1994-02-10 1996-08-09 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister NO963331L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19455394A 1994-02-10 1994-02-10
PCT/IB1994/000407 WO1995021836A1 (en) 1994-02-10 1994-12-08 5-heteroarylindole derivatives as benzodiazepine receptor site agonists and antagonists

Publications (2)

Publication Number Publication Date
NO963331D0 true NO963331D0 (no) 1996-08-09
NO963331L NO963331L (no) 1996-10-09

Family

ID=22718035

Family Applications (1)

Application Number Title Priority Date Filing Date
NO963331A NO963331L (no) 1994-02-10 1996-08-09 5-Heteroarylindol-derivater som benzodiazepin-reseptorsete-agonister og antagonister

Country Status (12)

Country Link
US (1) US5688809A (no)
EP (1) EP0743942A1 (no)
JP (1) JP2829788B2 (no)
KR (1) KR970701182A (no)
CN (1) CN1067386C (no)
AU (1) AU685881B2 (no)
CA (1) CA2183084A1 (no)
FI (1) FI950568A (no)
IL (1) IL112519A0 (no)
NO (1) NO963331L (no)
NZ (1) NZ276172A (no)
WO (1) WO1995021836A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1268137A (zh) 1997-07-03 2000-09-27 杜邦药品公司 治疗神经失调的咪唑并嘧啶和咪唑并吡啶
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
JP4769720B2 (ja) * 2003-08-21 2011-09-07 オーエスアイ・ファーマシューテイカルズ・エル・エル・シー Ｎ−置換ベンズイミダゾリルｃ−Ｋｉｔ阻害剤
DE602004017623D1 (de) 2003-08-21 2008-12-18 Osi Pharm Inc N-substituierte pyrazolyl-amidyl-benzimidazolyl-c-kit-inhibitoren
US7442709B2 (en) * 2003-08-21 2008-10-28 Osi Pharmaceuticals, Inc. N3-substituted imidazopyridine c-Kit inhibitors
CN101193867A (zh) * 2004-12-01 2008-06-04 Osi医药有限公司 N取代的苯并咪唑基c-Kit抑制剂和苯并咪唑组合库
US8889730B2 (en) 2012-04-10 2014-11-18 Pfizer Inc. Indole and indazole compounds that activate AMPK
JP6064062B2 (ja) 2013-03-15 2017-01-18 ファイザー・インク Ａｍｐｋを活性化させるインダゾール化合物
CN107750250B (zh) 2015-04-29 2021-09-07 詹森药业有限公司 吲哚酮化合物及其作为ampa受体调节剂的用途
KR20240017991A (ko) * 2015-04-29 2024-02-08 라포 테라퓨틱스, 인크. 아자벤즈이미다졸 및 ampa 수용체 조절제로서의 이의 용도
CN107567452B (zh) 2015-04-29 2020-07-07 詹森药业有限公司 咪唑并哌嗪和吡唑并嘧啶以及它们作为ampa受体调节剂的用途
JP6804469B2 (ja) 2015-04-29 2020-12-23 ヤンセン ファーマシューティカ エヌ．ベー． ベンゾイミダゾロン及びベンゾチアゾロン化合物並びにａｍｐａ受容体調節因子としてのそれらの使用
KR101831553B1 (ko) 2017-01-23 2018-02-22 계명대학교 산학협력단 전이성 유방암의 유용한 신규 화합물 및 이의 의학적 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5066654A (en) * 1990-10-22 1991-11-19 A. H. Robins Company, Incorporated 2-aryl-3-heterocyclicmethyl-3H-imidazo[4,5-b]pyridines as anxiolytics and anticonvulsants
GB9210400D0 (en) * 1992-05-15 1992-07-01 Merck Sharp & Dohme Therapeutic agents
TW251284B (no) * 1992-11-02 1995-07-11 Pfizer

Also Published As

Publication number Publication date
AU685881B2 (en) 1998-01-29
JP2829788B2 (ja) 1998-12-02
IL112519A0 (en) 1995-05-26
CN1067386C (zh) 2001-06-20
EP0743942A1 (en) 1996-11-27
FI950568A0 (fi) 1995-02-09
FI950568A (fi) 1995-08-11
CN1142823A (zh) 1997-02-12
AU1033995A (en) 1995-08-29
NZ276172A (en) 1998-02-26
US5688809A (en) 1997-11-18
NO963331L (no) 1996-10-09
JPH09501949A (ja) 1997-02-25
CA2183084A1 (en) 1995-08-17
WO1995021836A1 (en) 1995-08-17
KR970701182A (ko) 1997-03-17

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