NO961138L - Protein kinase C aktivatorer og anvendelse derav for å redusere ekspresjon av celleantigener - Google Patents
Protein kinase C aktivatorer og anvendelse derav for å redusere ekspresjon av celleantigenerInfo
- Publication number
- NO961138L NO961138L NO961138A NO961138A NO961138L NO 961138 L NO961138 L NO 961138L NO 961138 A NO961138 A NO 961138A NO 961138 A NO961138 A NO 961138A NO 961138 L NO961138 L NO 961138L
- Authority
- NO
- Norway
- Prior art keywords
- protein kinase
- activators
- cell antigen
- antigen expression
- tumor cells
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Sammensetning for oppregulering av ekspresjonen til celleantigener uten å indusere avgivelse som omfatter en proteinkinase C aktivator, en fremgangsmåte for detektering og behandling av tumorceller som omfatter kontakting av tumorccllene med en effektiv mengde av en proteinkinase C aktivator for oppregulering av ekspresjonen av antigenene til tumorceller, uten å indusere antigenavgivelse, og detektering av tilstedeværelse av nevnte antigen eller deretter videre kontakting av nevnte tumorceller med en effektiv mengde av et antistoff rettet mot nevnte antigen, er beskrevet.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/124,716 US5681860A (en) | 1993-09-21 | 1993-09-21 | Method of increasing expression of HLA, cell surface and TAA antigens of cells using 3-(N-acetylamino)-5-(N-decyl-N-methylamino)-benzyl alcohol |
PCT/US1994/010755 WO1995008326A1 (en) | 1993-09-21 | 1994-09-21 | Protein kinase c activators and their use in decreasing expression of cell antigens |
Publications (2)
Publication Number | Publication Date |
---|---|
NO961138D0 NO961138D0 (no) | 1996-03-20 |
NO961138L true NO961138L (no) | 1996-05-14 |
Family
ID=22416439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO961138A NO961138L (no) | 1993-09-21 | 1996-03-20 | Protein kinase C aktivatorer og anvendelse derav for å redusere ekspresjon av celleantigener |
Country Status (8)
Country | Link |
---|---|
US (4) | US5681860A (no) |
EP (1) | EP0730446A4 (no) |
JP (1) | JP2001525787A (no) |
KR (1) | KR960704539A (no) |
AU (1) | AU7841094A (no) |
CA (1) | CA2172383A1 (no) |
NO (1) | NO961138L (no) |
WO (1) | WO1995008326A1 (no) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5681860A (en) * | 1993-09-21 | 1997-10-28 | The Trustees Of Columbia University In The City Of New York | Method of increasing expression of HLA, cell surface and TAA antigens of cells using 3-(N-acetylamino)-5-(N-decyl-N-methylamino)-benzyl alcohol |
DK1246917T3 (da) * | 2000-01-13 | 2009-06-08 | Genentech Inc | Humane Stra6-polypeptider |
US6984522B2 (en) | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
WO2004000999A2 (en) * | 2002-06-21 | 2003-12-31 | California Institute Of Technology | Identification of a receptor controlling migration and metastasis of skin cancer cells |
US6981767B2 (en) * | 2003-01-15 | 2006-01-03 | Ssgii, Inc. | Printed item having an image with a high durability and/or resolution |
JP5429772B2 (ja) * | 2008-06-30 | 2014-02-26 | 株式会社アルバック | 電源装置 |
US10617161B2 (en) * | 2012-02-09 | 2020-04-14 | Medline Industries, Inc. | Garments for healthcare workers |
US11771869B2 (en) * | 2018-03-14 | 2023-10-03 | Philips Image Guided Therapy Corporation | Electromagnetic control for intraluminal sensing devices and associated devices, systems, and methods |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4925649A (en) * | 1987-06-12 | 1990-05-15 | The University Of Michigan | Radioiodinated diacylglycerol analogues and methods of use |
DE68910704T2 (de) * | 1988-01-13 | 1994-04-07 | Univ Arizona State | Immunmodulierende Bryostatine. |
WO1990005731A1 (en) * | 1988-11-24 | 1990-05-31 | University Of Queensland | Cytotoxic macromolecules |
US5681860A (en) * | 1993-09-21 | 1997-10-28 | The Trustees Of Columbia University In The City Of New York | Method of increasing expression of HLA, cell surface and TAA antigens of cells using 3-(N-acetylamino)-5-(N-decyl-N-methylamino)-benzyl alcohol |
-
1993
- 1993-09-21 US US08/124,716 patent/US5681860A/en not_active Expired - Lifetime
-
1994
- 1994-09-21 EP EP94929307A patent/EP0730446A4/en not_active Withdrawn
- 1994-09-21 JP JP50994295A patent/JP2001525787A/ja active Pending
- 1994-09-21 AU AU78410/94A patent/AU7841094A/en not_active Abandoned
- 1994-09-21 CA CA002172383A patent/CA2172383A1/en not_active Abandoned
- 1994-09-21 US US08/619,777 patent/US6187819B1/en not_active Expired - Fee Related
- 1994-09-21 KR KR1019960701475A patent/KR960704539A/ko not_active Application Discontinuation
- 1994-09-21 WO PCT/US1994/010755 patent/WO1995008326A1/en not_active Application Discontinuation
-
1996
- 1996-03-20 NO NO961138A patent/NO961138L/no unknown
-
1998
- 1998-12-07 US US09/206,798 patent/US6069174A/en not_active Expired - Lifetime
-
2001
- 2001-02-13 US US09/783,053 patent/US20020040062A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1995008326A1 (en) | 1995-03-30 |
EP0730446A4 (en) | 1999-01-20 |
CA2172383A1 (en) | 1995-03-30 |
US6187819B1 (en) | 2001-02-13 |
NO961138D0 (no) | 1996-03-20 |
EP0730446A1 (en) | 1996-09-11 |
US20020040062A1 (en) | 2002-04-04 |
AU7841094A (en) | 1995-04-10 |
US6069174A (en) | 2000-05-30 |
JP2001525787A (ja) | 2001-12-11 |
KR960704539A (ko) | 1996-10-09 |
US5681860A (en) | 1997-10-28 |
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