NO960545L - Behandling av skadelige virkninger i forbindelse med administrering av ekstracellulært hemoglobin - Google Patents

Behandling av skadelige virkninger i forbindelse med administrering av ekstracellulært hemoglobin

Info

Publication number
NO960545L
NO960545L NO960545A NO960545A NO960545L NO 960545 L NO960545 L NO 960545L NO 960545 A NO960545 A NO 960545A NO 960545 A NO960545 A NO 960545A NO 960545 L NO960545 L NO 960545L
Authority
NO
Norway
Prior art keywords
administration
effects associated
treatment
adverse effects
extracellular hemoglobin
Prior art date
Application number
NO960545A
Other languages
English (en)
Other versions
NO960545D0 (no
Inventor
Michael J Gerber
Original Assignee
Somatogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Somatogen Inc filed Critical Somatogen Inc
Publication of NO960545D0 publication Critical patent/NO960545D0/no
Publication of NO960545L publication Critical patent/NO960545L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41Porphyrin- or corrin-ring-containing peptides
    • A61K38/42Haemoglobins; Myoglobins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Den foreliggende oppfinnelse angår fremgangsmåter til å rette alvorlighet og frekvens av skadelige virkninger assosiert med administrering av ekstracellulært hemoglobin som omfatter å administrere et glatt muskelavslappende middel. Foretrukkede glatte muskelavslappende midler er terbutalin og nifedipin, som kan administreres i en profilaktisk behandling, vedvarende behandlingskur eller en intermitterende behandlingskur.
NO960545A 1993-08-13 1996-02-12 Behandling av skadelige virkninger i forbindelse med administrering av ekstracellulært hemoglobin NO960545L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10613893A 1993-08-13 1993-08-13
PCT/IB1994/000239 WO1995005167A2 (en) 1993-08-13 1994-08-09 Treatment of adverse effects associated with administration of extracellular hemoglobin

Publications (2)

Publication Number Publication Date
NO960545D0 NO960545D0 (no) 1996-02-12
NO960545L true NO960545L (no) 1996-02-29

Family

ID=22309699

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960545A NO960545L (no) 1993-08-13 1996-02-12 Behandling av skadelige virkninger i forbindelse med administrering av ekstracellulært hemoglobin

Country Status (8)

Country Link
US (1) US5750132A (no)
EP (2) EP0784983A3 (no)
JP (1) JPH09501441A (no)
AU (2) AU7194694A (no)
CA (1) CA2167716A1 (no)
IS (1) IS4198A (no)
NO (1) NO960545L (no)
WO (1) WO1995005167A2 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0700298B1 (en) * 1994-03-28 2003-06-18 BAXTER INTERNATIONAL INC. (a Delaware corporation) Therapeutic use of hemoglobin in the treatment of blood vessel blockage
US6894150B1 (en) * 1999-10-01 2005-05-17 Ross Walden Tye Non-pyrogenic, endotoxin-free, stroma-free tetrameric hemoglobin
FR2809624B1 (fr) * 2000-05-31 2002-08-02 Centre Nat Rech Scient Utilisation comme substitut sanguin d'une hemoglobine extracellulaire de poids moleculaire eleve
US7494974B2 (en) * 2006-10-24 2009-02-24 Ikor, Inc. Carboxymethylated cross-linked tetrameric hemoglobin
US7504377B2 (en) * 2006-10-23 2009-03-17 Ikor, Inc. Nitric oxide-blocked cross-linked tetrameric hemoglobin
WO2010128159A1 (en) * 2009-05-07 2010-11-11 Hemarina Novel heamoglobin and uses thereof
US9066933B2 (en) * 2011-09-06 2015-06-30 Billion King International Ltd. Oral delivery for hemoglobin based oxygen carriers

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4529719A (en) * 1983-05-04 1985-07-16 Tye Ross W Modified crosslinked stroma-free tetrameric hemoglobin
US4965065A (en) * 1986-04-29 1990-10-23 Bristol-Myers Squibb Company Gastroprotective process and compositions
US5043358A (en) * 1986-03-04 1991-08-27 Bristol-Myers Squibb Company Gastroprotective process
US4826811A (en) * 1986-06-20 1989-05-02 Northfield Laboratories, Inc. Acellular red blood cell substitute
EP0561245A1 (en) * 1987-05-16 1993-09-22 Somatogenetics International, Inc. Blood substitutes comprising recombinant hemoglobin
GB8711614D0 (en) * 1987-05-16 1987-06-24 Medical Res Council Proteins
US5545727A (en) * 1989-05-10 1996-08-13 Somatogen, Inc. DNA encoding fused di-alpha globins and production of pseudotetrameric hemoglobin
NL8901174A (nl) * 1989-05-10 1990-12-03 Het Hoofd Van De Afdeling Mili Hemoglobine-preparaat en gebruik daarvan.
US5173426A (en) * 1989-10-06 1992-12-22 Yale University DNAs encoding genetically engineered low oxygen affinity mutants of human hemoglobin
US5478806A (en) * 1989-11-22 1995-12-26 Enzon, Inc. Enhancement of antitumor therapy with hemoglobin-based conjugates
EP0537160B1 (en) * 1990-04-16 2002-08-21 Apex Bioscience, Inc. Expression of recombinant hemoglobin in yeast
JPH06504056A (ja) * 1990-12-20 1994-05-12 ザ・ユニバーシティ・オブ・アラバマ・リサーチ・ファウンデーション トランスジェニック架橋ヘモグロビン
US5295944A (en) * 1991-05-14 1994-03-22 Dana-Farber Cancer Institute Method for treating a tumor with ionizing radiation
WO1992020369A1 (en) * 1991-05-14 1992-11-26 Dana Farber Cancer Institute Use of hemoglobin in a method for the treatment of tumors with chemotherapeutic agents
US5624823A (en) * 1991-11-22 1997-04-29 The General Hospital Corporation DNA encoding procine interleukin-10

Also Published As

Publication number Publication date
IS4198A (is) 1995-02-14
NO960545D0 (no) 1996-02-12
US5750132A (en) 1998-05-12
EP0784983A2 (en) 1997-07-23
EP0784983A3 (en) 2001-03-21
WO1995005167A3 (en) 1995-04-13
EP0717619A1 (en) 1996-06-26
CA2167716A1 (en) 1995-02-23
AU7194694A (en) 1995-03-14
JPH09501441A (ja) 1997-02-10
WO1995005167A2 (en) 1995-02-23
AU7011098A (en) 1998-07-30

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