NO952160L - Humanized antibodies reactive with L-selectin - Google Patents
Humanized antibodies reactive with L-selectinInfo
- Publication number
- NO952160L NO952160L NO952160A NO952160A NO952160L NO 952160 L NO952160 L NO 952160L NO 952160 A NO952160 A NO 952160A NO 952160 A NO952160 A NO 952160A NO 952160 L NO952160 L NO 952160L
- Authority
- NO
- Norway
- Prior art keywords
- selectin
- humanized antibodies
- antibodies reactive
- reactive
- humanized
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
- C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98394692A | 1992-12-01 | 1992-12-01 | |
PCT/US1993/011612 WO1994012215A1 (en) | 1992-12-01 | 1993-11-30 | Humanized antibodies reactive with l-selectin |
Publications (2)
Publication Number | Publication Date |
---|---|
NO952160D0 NO952160D0 (en) | 1995-05-31 |
NO952160L true NO952160L (en) | 1995-07-31 |
Family
ID=25530200
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO952160A NO952160L (en) | 1992-12-01 | 1995-05-31 | Humanized antibodies reactive with L-selectin |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0671951A4 (en) |
JP (1) | JPH08503617A (en) |
KR (1) | KR100371784B1 (en) |
AU (1) | AU689090B2 (en) |
CA (1) | CA2149025A1 (en) |
CZ (1) | CZ140195A3 (en) |
FI (1) | FI952658A0 (en) |
HU (1) | HUT71790A (en) |
NO (1) | NO952160L (en) |
PL (1) | PL309249A1 (en) |
RU (1) | RU2151612C1 (en) |
WO (1) | WO1994012215A1 (en) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6010861A (en) * | 1994-08-03 | 2000-01-04 | Dgi Biotechnologies, Llc | Target specific screens and their use for discovering small organic molecular pharmacophores |
WO1996040942A1 (en) * | 1995-06-07 | 1996-12-19 | Cytel Corporation | Humanized antibodies to e-selectin |
AU746888B2 (en) * | 1995-08-17 | 2002-05-02 | Protein Design Labs, Inc. | Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage |
JP3604699B2 (en) * | 1995-08-17 | 2004-12-22 | プロテイン デザイン ラブス, インコーポレイティド | Anti-selectin antibodies for prevention of multiple organ failure after multiple trauma and for prevention of acute organ damage after extracorporeal blood circulation |
AU4594297A (en) * | 1996-09-27 | 1998-04-17 | Trustees Of Columbia University In The City Of New York, The | Methods for treating an ischemic disorder and improving stroke outcome |
US8128963B2 (en) | 1996-09-27 | 2012-03-06 | The Trustees Of Columbia University In The City Of New York | Methods for treating ischemic disorders using carbon monoxide |
EP0852951A1 (en) | 1996-11-19 | 1998-07-15 | Roche Diagnostics GmbH | Stable lyophilized monoclonal or polyclonal antibodies containing pharmaceuticals |
WO1999043353A2 (en) * | 1998-02-26 | 1999-09-02 | Boehringer Ingelheim Pharmaceuticals, Inc. | Combination anti-selectin and immunosuppressant therapy |
US20020029391A1 (en) * | 1998-04-15 | 2002-03-07 | Claude Geoffrey Davis | Epitope-driven human antibody production and gene expression profiling |
UY28886A1 (en) * | 2004-05-10 | 2005-12-30 | Boehringer Ingelheim Int | ANTIBODIES CONSISTING IN POLYPEPTIDES AND DERIVATIVES UNDERSTANDING THREE SEQUENCES CONCERNING THE FOLLOWING NUMBERS OF SEQ. ID: 1-3 AND 4-6; 7-9 AND 10-12 AND 13-15 OR 16-18 |
WO2007114319A1 (en) | 2006-03-31 | 2007-10-11 | Chugai Seiyaku Kabushiki Kaisha | Method for control of blood kinetics of antibody |
CN101500608A (en) | 2006-06-08 | 2009-08-05 | 中外制药株式会社 | Preventive or remedy for inflammatory disease |
CN101874042B9 (en) | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | Method for changing isoelectric point of antibody by using amino acid substitution of CDR |
WO2009041613A1 (en) | 2007-09-26 | 2009-04-02 | Chugai Seiyaku Kabushiki Kaisha | Modified antibody constant region |
CA2708065C (en) | 2007-12-05 | 2015-02-24 | Chugai Seiyaku Kabushiki Kaisha | Therapeutic agent for pruritus |
ES2834741T3 (en) | 2007-12-05 | 2021-06-18 | Chugai Pharmaceutical Co Ltd | Anti-NR10 antibody and its use |
LT2708559T (en) | 2008-04-11 | 2018-06-11 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly |
KR20160062207A (en) * | 2008-12-05 | 2016-06-01 | 추가이 세이야쿠 가부시키가이샤 | Anti-NR10 antibody and use thereof |
JP2010210772A (en) * | 2009-03-13 | 2010-09-24 | Dainippon Screen Mfg Co Ltd | Method of manufacturing liquid crystal display device |
EP2409991B1 (en) | 2009-03-19 | 2017-05-03 | Chugai Seiyaku Kabushiki Kaisha | Antibody constant region variant |
TWI544077B (en) | 2009-03-19 | 2016-08-01 | Chugai Pharmaceutical Co Ltd | Antibody constant region change body |
CA2806233C (en) * | 2010-07-26 | 2021-12-07 | Trianni, Inc. | Transgenic animals and methods of use |
NZ606824A (en) | 2010-08-02 | 2015-05-29 | Regeneron Pharma | Mice that make binding proteins comprising vl domains |
EP2647706B1 (en) | 2010-11-30 | 2023-05-17 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
EP2654781B1 (en) * | 2010-12-21 | 2018-01-24 | Selexys Pharmaceuticals Corporation | Anti-p-selectin antibodies and methods of their use and identification |
PL2578688T5 (en) | 2011-02-25 | 2023-05-29 | Regeneron Pharmaceuticals, Inc. | ADAM6 mice |
MY172718A (en) | 2011-08-05 | 2019-12-11 | Regeneron Pharma | Humanized universal light chain mice |
CA2859408C (en) | 2011-12-20 | 2020-06-16 | Regeneron Pharmaceuticals, Inc. | Humanized light chain mice |
KR102436654B1 (en) | 2012-06-12 | 2022-08-26 | 리제너론 파마슈티칼스 인코포레이티드 | Humanized non-human animals with restricted immunoglobulin heavy chain loci |
AU2015231025A1 (en) | 2014-03-21 | 2016-09-15 | Regeneron Pharmaceuticals, Inc. | Vl antigen binding proteins exhibiting distinct binding characteristics |
KR102601491B1 (en) | 2014-03-21 | 2023-11-13 | 리제너론 파마슈티칼스 인코포레이티드 | Non-human animals that make single domain binding proteins |
CN107438622A (en) | 2015-03-19 | 2017-12-05 | 瑞泽恩制药公司 | Non-human animals selected for antigen-binding light chain variable regions |
BR112017022101A2 (en) | 2015-04-14 | 2018-07-31 | Chugai Seiyaku Kabushiki Kaisha | pharmaceutical composition for prevention and / or treatment of atopic dermatitis containing il-31 antagonist as an active ingredient |
BR112022006590A2 (en) | 2019-11-20 | 2022-06-28 | Chugai Pharmaceutical Co Ltd | PREPARATION CONTAINING ANTIBODIES |
WO2024194605A1 (en) | 2023-03-17 | 2024-09-26 | Quell Therapeutics Limited | Treg therapy |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
NZ236792A (en) * | 1990-01-19 | 1993-05-26 | Merck & Co Inc | Recombinant human anti-cd18 antibody, murine 1b4 heavy or light chain variable region, dna, vectors, mammalian host and pharmaceutical compositions |
-
1993
- 1993-11-30 EP EP94903357A patent/EP0671951A4/en not_active Withdrawn
- 1993-11-30 WO PCT/US1993/011612 patent/WO1994012215A1/en not_active Application Discontinuation
- 1993-11-30 HU HU9501564A patent/HUT71790A/en unknown
- 1993-11-30 RU RU95115405/14A patent/RU2151612C1/en not_active IP Right Cessation
- 1993-11-30 KR KR1019950702196A patent/KR100371784B1/en not_active IP Right Cessation
- 1993-11-30 JP JP6513460A patent/JPH08503617A/en not_active Ceased
- 1993-11-30 CZ CZ951401A patent/CZ140195A3/en unknown
- 1993-11-30 AU AU57327/94A patent/AU689090B2/en not_active Ceased
- 1993-11-30 PL PL93309249A patent/PL309249A1/en unknown
- 1993-11-30 CA CA002149025A patent/CA2149025A1/en not_active Abandoned
-
1995
- 1995-05-31 FI FI952658A patent/FI952658A0/en not_active IP Right Cessation
- 1995-05-31 NO NO952160A patent/NO952160L/en unknown
Also Published As
Publication number | Publication date |
---|---|
PL309249A1 (en) | 1995-10-02 |
WO1994012215A1 (en) | 1994-06-09 |
FI952658A (en) | 1995-05-31 |
HU9501564D0 (en) | 1995-07-28 |
RU2151612C1 (en) | 2000-06-27 |
NO952160D0 (en) | 1995-05-31 |
AU689090B2 (en) | 1998-03-26 |
EP0671951A4 (en) | 1997-05-21 |
CZ140195A3 (en) | 1996-06-12 |
HUT71790A (en) | 1996-02-28 |
CA2149025A1 (en) | 1994-06-09 |
FI952658A0 (en) | 1995-05-31 |
JPH08503617A (en) | 1996-04-23 |
EP0671951A1 (en) | 1995-09-20 |
AU5732794A (en) | 1994-06-22 |
KR100371784B1 (en) | 2003-07-22 |
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