FI952658A - With L-selectin reactive humanized antibodies - Google Patents

With L-selectin reactive humanized antibodies Download PDF

Info

Publication number
FI952658A
FI952658A FI952658A FI952658A FI952658A FI 952658 A FI952658 A FI 952658A FI 952658 A FI952658 A FI 952658A FI 952658 A FI952658 A FI 952658A FI 952658 A FI952658 A FI 952658A
Authority
FI
Finland
Prior art keywords
humanized antibodies
selectin
reactive humanized
selectin reactive
reactive
Prior art date
Application number
FI952658A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI952658A0 (en
Inventor
Man Sung Co
Original Assignee
Protein Design Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protein Design Labs Inc filed Critical Protein Design Labs Inc
Publication of FI952658A publication Critical patent/FI952658A/en
Publication of FI952658A0 publication Critical patent/FI952658A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI952658A 1992-12-01 1995-05-31 With L-selectin reactive humanized antibodies FI952658A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98394692A 1992-12-01 1992-12-01
PCT/US1993/011612 WO1994012215A1 (en) 1992-12-01 1993-11-30 Humanized antibodies reactive with l-selectin

Publications (2)

Publication Number Publication Date
FI952658A true FI952658A (en) 1995-05-31
FI952658A0 FI952658A0 (en) 1995-05-31

Family

ID=25530200

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952658A FI952658A0 (en) 1992-12-01 1995-05-31 With L-selectin reactive humanized antibodies

Country Status (12)

Country Link
EP (1) EP0671951A4 (en)
JP (1) JPH08503617A (en)
KR (1) KR100371784B1 (en)
AU (1) AU689090B2 (en)
CA (1) CA2149025A1 (en)
CZ (1) CZ140195A3 (en)
FI (1) FI952658A0 (en)
HU (1) HUT71790A (en)
NO (1) NO952160L (en)
PL (1) PL309249A1 (en)
RU (1) RU2151612C1 (en)
WO (1) WO1994012215A1 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
AU6155896A (en) * 1995-06-07 1996-12-30 Cytel Corporation Humanized antibodies to e-selectin
AU746888B2 (en) * 1995-08-17 2002-05-02 Protein Design Labs, Inc. Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage
CA2229140A1 (en) * 1995-08-17 1997-02-27 Protein Design Labs, Inc. Anti-selectin antibodies for prevention of multiple organ failure and acute organ damage
US8128963B2 (en) 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
JP2001501612A (en) * 1996-09-27 2001-02-06 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク Methods for treating ischemic disease and improving post-stroke symptoms
EP0852951A1 (en) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stable lyophilized monoclonal or polyclonal antibodies containing pharmaceuticals
WO1999043353A2 (en) * 1998-02-26 1999-09-02 Boehringer Ingelheim Pharmaceuticals, Inc. Combination anti-selectin and immunosuppressant therapy
US20020029391A1 (en) * 1998-04-15 2002-03-07 Claude Geoffrey Davis Epitope-driven human antibody production and gene expression profiling
MY148646A (en) * 2004-05-10 2013-05-15 Abgenomics Cooperatief Ua Anti-psgl-1 antibodies
US11046784B2 (en) 2006-03-31 2021-06-29 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
CN103272232B (en) 2006-06-08 2018-07-24 中外制药株式会社 The prevention of inflammatory disease or medicine
SI2202245T1 (en) 2007-09-26 2016-10-28 Chugai Seiyaku Kabushiki Kaisha Method of modifying isoelectric point of antibody via amino acid substitution in cdr
ES2687808T3 (en) 2007-09-26 2018-10-29 Chugai Seiyaku Kabushiki Kaisha Constant region of modified antibody
EP2241332A4 (en) 2007-12-05 2011-01-26 Chugai Pharmaceutical Co Ltd Therapeutic agent for pruritus
KR101643005B1 (en) 2007-12-05 2016-07-28 추가이 세이야쿠 가부시키가이샤 Anti-NR10 antibody and use thereof
PL2275443T3 (en) 2008-04-11 2016-05-31 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
KR20160062207A (en) * 2008-12-05 2016-06-01 추가이 세이야쿠 가부시키가이샤 Anti-NR10 antibody and use thereof
JP2010210772A (en) * 2009-03-13 2010-09-24 Dainippon Screen Mfg Co Ltd Method of manufacturing liquid crystal display device
JP5717624B2 (en) 2009-03-19 2015-05-13 中外製薬株式会社 Antibody constant region variants
TWI544077B (en) 2009-03-19 2016-08-01 Chugai Pharmaceutical Co Ltd Antibody constant region change body
JP6482757B2 (en) * 2010-07-26 2019-03-13 トリアンニ インコーポレイテッドＴｒｉａｎｎｉ，Ｉｎｃ． Transgenic animals and methods of use
EP3960865A1 (en) 2010-08-02 2022-03-02 Regeneron Pharmaceuticals, Inc. Mice that make binding proteins comprising vl domains
MX365235B (en) 2010-11-30 2019-05-28 Chugai Pharmaceutical Co Ltd Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly.
CN103874503A (en) * 2010-12-21 2014-06-18 瑟莱克斯制药公司 Anti-P-selectin antibodies and methods of their use and identification
US8642835B2 (en) * 2011-02-25 2014-02-04 Regeneron Pharmaceuticals, Inc. ADAM6 mice
SG2014007686A (en) 2011-08-05 2014-03-28 Regeneron Pharma Humanized universal light chain mice
BR112014015238B1 (en) 2011-12-20 2022-11-16 Regeneron Pharmaceuticals, Inc EX VIVO METHOD FOR PREPARING AN ANTIBODY THAT BINDS TO AN ANTIGEN OF INTEREST, INCLUDING IDENTIFYING NUCLEIC ACID SEQUENCES FROM MOUSE B LYMPHOCYTES GENETICALLY MODIFIED BY PLACING AN ADAM6 GENE
PT2858487T (en) 2012-06-12 2020-01-15 Regeneron Pharma Humanized non-human animals with restricted immunoglobulin heavy chain loci
WO2015143414A2 (en) 2014-03-21 2015-09-24 Regeneron Pharmaceuticals, Inc. Non-human animals that make single domain binding proteins
EP3119811B1 (en) 2014-03-21 2019-10-30 Regeneron Pharmaceuticals, Inc. Vl antigen binding proteins exhibiting distinct binding characteristics
CN107438622A (en) 2015-03-19 2017-12-05 瑞泽恩制药公司 Non-human animal of the selection with reference to the light chain variable district of antigen
MX2017013141A (en) 2015-04-14 2018-02-21 Chugai Pharmaceutical Co Ltd Pharmaceutical composition for prevention and/or treatment of atopic dermatitis containing il-31 antagonist as active ingredient.
JP6845973B1 (en) 2019-11-20 2021-03-24 中外製薬株式会社 Antibody-containing preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
NZ236792A (en) * 1990-01-19 1993-05-26 Merck & Co Inc Recombinant human anti-cd18 antibody, murine 1b4 heavy or light chain variable region, dna, vectors, mammalian host and pharmaceutical compositions

Also Published As

Publication number Publication date
WO1994012215A1 (en) 1994-06-09
NO952160L (en) 1995-07-31
PL309249A1 (en) 1995-10-02
JPH08503617A (en) 1996-04-23
HU9501564D0 (en) 1995-07-28
FI952658A0 (en) 1995-05-31
CZ140195A3 (en) 1996-06-12
EP0671951A4 (en) 1997-05-21
RU2151612C1 (en) 2000-06-27
KR100371784B1 (en) 2003-07-22
HUT71790A (en) 1996-02-28
AU689090B2 (en) 1998-03-26
NO952160D0 (en) 1995-05-31
EP0671951A1 (en) 1995-09-20
AU5732794A (en) 1994-06-22
CA2149025A1 (en) 1994-06-09

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