NO932212L - POLYAMINMEDIKAMENT-RESIN COMPLEXES - Google Patents
POLYAMINMEDIKAMENT-RESIN COMPLEXESInfo
- Publication number
- NO932212L NO932212L NO93932212A NO932212A NO932212L NO 932212 L NO932212 L NO 932212L NO 93932212 A NO93932212 A NO 93932212A NO 932212 A NO932212 A NO 932212A NO 932212 L NO932212 L NO 932212L
- Authority
- NO
- Norway
- Prior art keywords
- drug
- cation exchange
- resin
- polyaminmedikament
- resin complex
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
- A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Det er angitt orale farmasøytiske preparater som omfatter et farmakologisk aktivt polyamin-medikament bundet til en kation- bytter-harpiks for å tilveiebringe et medikament-harpikskompleks med et medikament-innhold større enn en amin-ekviva- lent per ekvivalent kationbytter-kapasitet. Medikament- harpikskomplekset er eventuelt dekket med et vannpermeabelt diffusjonsbarriere-overtrekk som er uoppløselig i mage- og tarm-fluider, og tilveiebringer derved en kontrollerbar medikamentfrigivelse under de forhold som påtreffes i mage- og tarm-systemet.Oral pharmaceutical compositions are disclosed which comprise a pharmacologically active polyamine drug bound to a cation exchange resin to provide a drug-resin complex having a drug content greater than one amine equivalent per equivalent cation exchange capacity. The drug-resin complex is optionally covered with a water-permeable diffusion barrier coating which is insoluble in gastrointestinal fluids, thereby providing a controllable drug release under the conditions encountered in the gastrointestinal system.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63229090A | 1990-12-21 | 1990-12-21 | |
PCT/US1991/009463 WO1992011038A1 (en) | 1990-12-21 | 1991-12-16 | Polyamine drug-resin complexes |
Publications (2)
Publication Number | Publication Date |
---|---|
NO932212D0 NO932212D0 (en) | 1993-06-16 |
NO932212L true NO932212L (en) | 1993-08-20 |
Family
ID=24534913
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO93932212A NO932212L (en) | 1990-12-21 | 1993-06-16 | POLYAMINMEDIKAMENT-RESIN COMPLEXES |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP0563294A1 (en) |
JP (1) | JPH06504059A (en) |
CN (1) | CN1063221A (en) |
AU (1) | AU663695B2 (en) |
BR (1) | BR9107173A (en) |
CA (1) | CA2098200A1 (en) |
CZ (1) | CZ119793A3 (en) |
FI (1) | FI932842A0 (en) |
HU (1) | HUT74642A (en) |
IE (1) | IE914513A1 (en) |
MX (1) | MX9102753A (en) |
MY (1) | MY107811A (en) |
NO (1) | NO932212L (en) |
NZ (1) | NZ241097A (en) |
PT (1) | PT99912A (en) |
SK (1) | SK59493A3 (en) |
WO (1) | WO1992011038A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995005161A1 (en) * | 1993-08-13 | 1995-02-23 | Vitaphore Corporation | Hydrogel-based microsphere drug delivery systems |
JP4619457B2 (en) * | 1993-11-18 | 2011-01-26 | シルテックス、メディカル、リミテッド | Sustained release formulation |
ES2097087B1 (en) * | 1994-08-01 | 1997-12-16 | Univ Sevilla | CONTROLLED RELEASE SYSTEM FOR MORPHINE AND OTHER PHARMACLES SOLUBLE IN WATER BY COMPLEXING WITH POLYMERIC SUBSTANCES. |
CA2269679A1 (en) * | 1996-12-20 | 1998-07-02 | Warner-Lambert Company | Antitussive drugs delivered by partially coated ion exchange resins |
UA73092C2 (en) * | 1998-07-17 | 2005-06-15 | Брістол-Майерс Сквібб Компані | Tablets with enteric coating and method for their manufacture |
KR20020016069A (en) * | 2000-08-24 | 2002-03-04 | 민경윤 | An oral composition of a macrolide antibiotic and a process for preparing same |
MXPA06002300A (en) | 2003-09-03 | 2006-05-19 | Mallinckrodt Inc | Granular sustained release preparation and production thereof. |
CN100411629C (en) * | 2006-08-28 | 2008-08-20 | 浙江大学 | Slow-released type iron-complement agent, prepn. method and use thereof |
CN100415297C (en) * | 2006-08-28 | 2008-09-03 | 浙江大学 | Zinc supplements based on cation exchange resin and its preparation method and use |
EP2500016A1 (en) | 2011-03-18 | 2012-09-19 | Laboratorios Del. Dr. Esteve, S.A. | Doxylamine resinate complex |
WO2015076821A1 (en) * | 2013-11-22 | 2015-05-28 | Tris Pharma, Inc. | Novel clonidine formulation |
US11918689B1 (en) | 2020-07-28 | 2024-03-05 | Tris Pharma Inc | Liquid clonidine extended release composition |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4221778A (en) * | 1979-01-08 | 1980-09-09 | Pennwalt Corporation | Prolonged release pharmaceutical preparations |
CA1236023A (en) * | 1984-07-18 | 1988-05-03 | Yegnaswami Raghunathan | Controlled release pharmaceutical preparations |
US4894239A (en) * | 1987-06-02 | 1990-01-16 | Takeda Chemical Industries, Ltd. | Sustained-release preparation and production thereof |
IL90245A (en) * | 1988-05-11 | 1994-04-12 | Glaxo Group Ltd | Resin adsorbate comprising ranitidine together with a synthetic cation exchange resin, its preparation and pharmaceutical compositions containing it |
FR2634377B1 (en) * | 1988-06-30 | 1991-09-27 | Cortial | NOVEL EXTENDED RELEASE PHARMACEUTICAL FORM BASED ON AN ACTIVE RESIN-PRINCIPLE COMPLEX |
US4996047A (en) * | 1988-11-02 | 1991-02-26 | Richardson-Vicks, Inc. | Sustained release drug-resin complexes |
-
1991
- 1991-12-16 CA CA002098200A patent/CA2098200A1/en not_active Abandoned
- 1991-12-16 WO PCT/US1991/009463 patent/WO1992011038A1/en not_active Application Discontinuation
- 1991-12-16 BR BR919107173A patent/BR9107173A/en not_active Application Discontinuation
- 1991-12-16 JP JP4503722A patent/JPH06504059A/en active Pending
- 1991-12-16 AU AU91687/91A patent/AU663695B2/en not_active Ceased
- 1991-12-16 HU HU9301819A patent/HUT74642A/en unknown
- 1991-12-16 SK SK594-93A patent/SK59493A3/en unknown
- 1991-12-16 CZ CS931197A patent/CZ119793A3/en unknown
- 1991-12-16 EP EP92903625A patent/EP0563294A1/en not_active Withdrawn
- 1991-12-20 NZ NZ241097A patent/NZ241097A/en unknown
- 1991-12-20 PT PT99912A patent/PT99912A/en not_active Application Discontinuation
- 1991-12-20 IE IE451391A patent/IE914513A1/en not_active Application Discontinuation
- 1991-12-20 MX MX9102753A patent/MX9102753A/en unknown
- 1991-12-20 MY MYPI91002365A patent/MY107811A/en unknown
- 1991-12-21 CN CN91109058A patent/CN1063221A/en active Pending
-
1993
- 1993-06-16 NO NO93932212A patent/NO932212L/en unknown
- 1993-06-18 FI FI932842A patent/FI932842A0/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU9168791A (en) | 1992-07-22 |
AU663695B2 (en) | 1995-10-19 |
BR9107173A (en) | 1993-11-16 |
HUT74642A (en) | 1997-01-28 |
JPH06504059A (en) | 1994-05-12 |
CA2098200A1 (en) | 1992-06-21 |
MX9102753A (en) | 1992-06-30 |
HU9301819D0 (en) | 1993-09-28 |
NO932212D0 (en) | 1993-06-16 |
EP0563294A1 (en) | 1993-10-06 |
FI932842A (en) | 1993-06-18 |
PT99912A (en) | 1993-01-29 |
SK59493A3 (en) | 1993-11-10 |
WO1992011038A1 (en) | 1992-07-09 |
NZ241097A (en) | 1994-11-25 |
FI932842A0 (en) | 1993-06-18 |
CN1063221A (en) | 1992-08-05 |
IE914513A1 (en) | 1992-07-01 |
CZ119793A3 (en) | 1994-01-19 |
MY107811A (en) | 1996-06-29 |
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