NO922155L - Peptider og antistoffer som inhiberer integrinligandbinding - Google Patents

Peptider og antistoffer som inhiberer integrinligandbinding

Info

Publication number
NO922155L
NO922155L NO92922155A NO922155A NO922155L NO 922155 L NO922155 L NO 922155L NO 92922155 A NO92922155 A NO 92922155A NO 922155 A NO922155 A NO 922155A NO 922155 L NO922155 L NO 922155L
Authority
NO
Norway
Prior art keywords
integrinigandand
peptides
binding
antibodies inhibiting
antibodies
Prior art date
Application number
NO92922155A
Other languages
English (en)
Norwegian (no)
Other versions
NO922155D0 (no
Inventor
Edward F Plow
Souza Stanley E D
Mark H Ginsberg
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of NO922155D0 publication Critical patent/NO922155D0/no
Publication of NO922155L publication Critical patent/NO922155L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70557—Integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NO92922155A 1989-12-01 1992-05-29 Peptider og antistoffer som inhiberer integrinligandbinding NO922155L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/444,777 US5196511A (en) 1989-12-01 1989-12-01 Peptides and antibodies that inhibit integrin-ligand binding
PCT/US1990/006954 WO1991007977A1 (en) 1989-12-01 1990-11-29 Peptides and antibodies that inhibit integrin-ligand binding

Publications (2)

Publication Number Publication Date
NO922155D0 NO922155D0 (no) 1992-05-29
NO922155L true NO922155L (no) 1992-07-31

Family

ID=23766316

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92922155A NO922155L (no) 1989-12-01 1992-05-29 Peptider og antistoffer som inhiberer integrinligandbinding

Country Status (8)

Country Link
US (1) US5196511A (fi)
EP (1) EP0502124A4 (fi)
JP (1) JP3315403B2 (fi)
AU (1) AU645770B2 (fi)
CA (1) CA2069902A1 (fi)
FI (1) FI922454A (fi)
NO (1) NO922155L (fi)
WO (1) WO1991007977A1 (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5773574A (en) * 1990-12-03 1998-06-30 The Scripps Research Institute Polypeptides for promoting cell attachment
DE69229948T2 (de) 1991-04-30 2000-03-16 The Scripps Research Institute hGPIIb-FRAGMENTE UND IHRE VERWENDUNG IN IN-VITRO-VERFAHREN ZUR BESTIMMUNG VON IN VIVO STATTFINDENDEN THROMBOTISCHEN EREIGNISSEN
SK57693A3 (en) * 1992-06-18 1994-07-06 Merck Patent Gmbh Linear peptides and pharmaceutical agents on their base
ES2169724T3 (es) * 1992-10-02 2002-07-16 Alberta Res Council Propiedades antiinflamatorias, tolerogenicas e inmunoestimulantes de peptidos que enlazan carbohidratos.
US5453272A (en) * 1992-10-02 1995-09-26 Alberta Research Council Lectin derived carbohydrate binding-peptide
DE4310632A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Lineare Adhäsionsinhibitoren
US5594120A (en) * 1994-02-18 1997-01-14 Brigham And Women's Hospital, Inc. Integrin alpha subunit
US5523209A (en) * 1994-03-14 1996-06-04 The Scripps Research Institute Methods for identifying inhibitors of integrin activation
EP0762886A4 (en) * 1994-04-19 1999-03-31 Univ Kansas ICAM-1 / LFA-1 SHORT CHAIN PEPTIDES AND METHODS FOR USE THEREOF
US5610281A (en) 1994-05-03 1997-03-11 Brigham & Women's Hospital, Inc. Antibodies for modulating heterotypic E-cadherin interactions with human T lymphocytes
US5817750A (en) * 1995-08-28 1998-10-06 La Jolla Cancer Research Foundation Structural mimics of RGD-binding sites
JP2002515873A (ja) * 1996-04-26 2002-05-28 ザ ユニバーシティ オブ カンザス 免疫寛容を誘起するペプチド組成物およびその利用方法
WO1998032771A1 (fr) * 1997-01-29 1998-07-30 Toray Industries, Inc. Proteines chimeres, complexes heterodimeres de ces proteines et substituant de plaquette
US6046316A (en) * 1997-12-09 2000-04-04 Wayne State University Nucleic acid encoding truncated integrins
US7618630B2 (en) * 1998-09-14 2009-11-17 Board Of Regents, The University Of Texas System Methods of treating multiple myeloma and myeloma-induced bone resorption using integrin antagonists
CA2439852A1 (en) * 2001-03-02 2002-09-12 Christine Dingivan Methods of preventing or treating inflammatory or autoimmune disorders by administering integrin alphav beta3 antagonists
JP2005525368A (ja) * 2002-03-04 2005-08-25 メディミューン，インコーポレーテッド インテグリンαｖβ３アンタゴニストをＨＭＧ−ＣｏＡ還元酵素阻害剤またはビスフォスフォネートと併用投与する障害の予防または治療方法
JP2005533001A (ja) * 2002-03-04 2005-11-04 メディミューン，インコーポレーテッド インテグリンαｖβ３アンタゴニストを他の物質と併用投与する癌の予防または治療方法
JP2005535572A (ja) 2002-04-12 2005-11-24 メディミューン，インコーポレーテッド 組換え抗インターロイキン−９抗体
US20040176272A1 (en) * 2003-01-30 2004-09-09 Medimmune, Inc. Uses of integrin alphavbeta3 antagonists
CA2521826C (en) 2003-04-11 2013-08-06 Jennifer L. Reed Recombinant il-9 antibodies and uses thereof
US7358331B2 (en) * 2003-05-19 2008-04-15 Elan Pharmaceuticals, Inc. Truncated fragments of alpha-synuclein in Lewy body disease
US7351739B2 (en) * 2004-04-30 2008-04-01 Wellgen, Inc. Bioactive compounds and methods of uses thereof
WO2006047639A2 (en) 2004-10-27 2006-05-04 Medimmune, Inc. Modulation of antibody specificity by tailoring the affinity to cognate antigens
ES2388068T3 (es) * 2004-12-23 2012-10-08 Molmed Spa Producto de conjugación
AP2809A (en) * 2005-11-18 2013-12-31 Glenmark Pharmaceuticals Sa Anti-Alpha2 Integrin antibodies and their uses
WO2008008373A2 (en) 2006-07-11 2008-01-17 Arubor Corp Rhinosinusitis prevention and therapy with proinflammatory cytokine inhibitors
US20080039362A1 (en) * 2006-08-09 2008-02-14 Afmedica, Inc. Combination drug therapy for reducing scar tissue formation
LT2068889T (lt) 2006-08-10 2020-02-10 Roy C. Levitt Anakinra, naudojama bronchiolito obliteranso sindromo gydymui

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114842A (en) * 1987-07-08 1992-05-19 The Scripps Research Institute Peptides and antibodies that inhibit platelet adhesion

Also Published As

Publication number Publication date
JP3315403B2 (ja) 2002-08-19
FI922454A0 (fi) 1992-05-27
JPH05502228A (ja) 1993-04-22
NO922155D0 (no) 1992-05-29
WO1991007977A1 (en) 1991-06-13
CA2069902A1 (en) 1991-06-02
AU6911391A (en) 1991-06-26
EP0502124A1 (en) 1992-09-09
AU645770B2 (en) 1994-01-27
EP0502124A4 (en) 1993-04-28
US5196511A (en) 1993-03-23
FI922454A (fi) 1992-05-27

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