NO902084L - PROCEDURE FOR PREPARING SUBSTITUTED PYROL ROLE COMPOUNDS. - Google Patents
PROCEDURE FOR PREPARING SUBSTITUTED PYROL ROLE COMPOUNDS.Info
- Publication number
- NO902084L NO902084L NO90902084A NO902084A NO902084L NO 902084 L NO902084 L NO 902084L NO 90902084 A NO90902084 A NO 90902084A NO 902084 A NO902084 A NO 902084A NO 902084 L NO902084 L NO 902084L
- Authority
- NO
- Norway
- Prior art keywords
- role
- compounds
- procedure
- preparing substituted
- pyrol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3915450A DE3915450A1 (en) | 1989-05-11 | 1989-05-11 | SUBSTITUTED PYRROL COMPOUNDS AND THEIR USE IN PHARMACY |
Publications (4)
Publication Number | Publication Date |
---|---|
NO902084D0 NO902084D0 (en) | 1990-05-10 |
NO902084L true NO902084L (en) | 1990-11-12 |
NO174892B NO174892B (en) | 1994-04-18 |
NO174892C NO174892C (en) | 1994-07-27 |
Family
ID=6380477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO902084A NO174892C (en) | 1989-05-11 | 1990-05-10 | Analogous Process for Preparation of Therapeutically Active, Substituted Dihydropyrrolizine Compounds |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0397175B1 (en) |
JP (1) | JP2796876B2 (en) |
KR (1) | KR0173455B1 (en) |
AR (1) | AR246256A1 (en) |
AT (1) | ATE98246T1 (en) |
AU (1) | AU637098B2 (en) |
CA (1) | CA2016501C (en) |
DD (1) | DD294260A5 (en) |
DE (2) | DE3915450A1 (en) |
DK (1) | DK0397175T3 (en) |
ES (1) | ES2062160T3 (en) |
FI (1) | FI95258C (en) |
NO (1) | NO174892C (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0679157T3 (en) * | 1993-01-15 | 1998-07-27 | Searle & Co | Novel 3,4-diarylthiophenes and analogs thereof for use as anti-inflammatory agents |
US6492413B2 (en) | 1993-01-15 | 2002-12-10 | G.D. Searle & Co. | 3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents |
US5474995A (en) * | 1993-06-24 | 1995-12-12 | Merck Frosst Canada, Inc. | Phenyl heterocycles as cox-2 inhibitors |
DE4338770A1 (en) * | 1993-11-12 | 1995-05-18 | Matthias Dr Lehr | Indole-2-alkanoic acids and their derivatives as inhibitors of phospholipase A¶2¶ |
DE4419247A1 (en) * | 1994-06-01 | 1995-12-07 | Merckle Gmbh | New pyrrolizine keto-acid, keto-ester and carboxamide derivs. |
DE4419246A1 (en) * | 1994-06-01 | 1995-12-07 | Merckle Gmbh | New hetero-aryl substd. pyrrolizine derivs. |
DE4419315A1 (en) * | 1994-06-01 | 1995-12-07 | Merckle Gmbh | New hetero- and oxo-pyrrolizine derivs. |
KR100482268B1 (en) * | 1996-08-01 | 2005-04-14 | 메르클레 게엠베하 | Acylpyrroldicarboxylic acids and acylindoldicarboxylic acids and their derivatives and inhibitors of the cytosolic phospholipase a2 |
EP1252164B1 (en) * | 2000-01-28 | 2004-03-24 | Merckle Gmbh | Method for producing 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizine-5-yl acetic acid |
DE10004157A1 (en) * | 2000-02-01 | 2001-08-02 | Merckle Gmbh Chem Pharm Fabrik | New pyridyl- or pyrimidinyl-substituted bicyclic pyrrole derivatives, are cyclokine release inhibitors useful for treating immune system-related disorders, e.g. cancer, multiple sclerosis or arthritis |
KR20020007836A (en) * | 2000-07-19 | 2002-01-29 | 신덕호 | Golf ball |
DE10141285A1 (en) | 2001-08-23 | 2003-03-27 | Merckle Gmbh | Process for the preparation of 6- (4-chlorophenyl) -2,2-dimethyl-7-phnyl-2,3-dihydro-1H-pyrrolizin-5-yl-acetic acid |
DE102005012971A1 (en) | 2005-03-21 | 2006-09-28 | Merckle Gmbh | Polymorphic form of 6- (4-chlorophenyl) -2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine-5-yl-acetic acid |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1156473A (en) * | 1965-04-30 | 1969-06-25 | Firmenich & Cie | Thiazole Alcohols |
AU429651B2 (en) * | 1968-08-08 | 1972-11-01 | Commonwealth Scientific And Industrial Research Organization | Antiviral 6, 7 dihydro 5h pyrrolizines and related compounds |
DE2062984A1 (en) * | 1970-12-21 | 1972-06-22 | Messerschmitt, Thilo, 8094 Reitmehring; Dobeneck, Henning von, 8021 Icking | 2-unsubstd-5-formyl-pyrrole prepn - by catalytic hydrogenation of 2-halo-5-formyl-pyrroles |
DE2261965A1 (en) * | 1971-12-23 | 1973-06-28 | Continental Pharma | DERIVATIVES OF PYRROE ACETIC ACID AND ITS SALTS AND OF PYRROL ACETONITRILE, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS, PHARMACEUTICAL PRODUCTS CONTAINING THESE COMPOUNDS AND USES OF THESE COMPOUNDS AND PRODUCTS |
JPS5217074B2 (en) * | 1972-04-25 | 1977-05-13 | ||
JPS6011899B2 (en) * | 1978-12-27 | 1985-03-28 | 財団法人相模中央化学研究所 | Method for producing pyrrole acetic acid derivative |
JPS5687558A (en) * | 1979-11-27 | 1981-07-16 | Mcneilab Inc | Manufacture of pyrrolee22acetic acids |
US4284562A (en) * | 1979-11-27 | 1981-08-18 | Mcneilab, Inc. | Process for preparing pyrrole-2-acetic acids |
JPS56100784A (en) * | 1980-01-16 | 1981-08-12 | Yoshitomi Pharmaceut Ind Ltd | Indolizine derivative |
US4327221A (en) * | 1980-10-15 | 1982-04-27 | American Home Products Corporation | 2-Substituted-3-hydroxythiazolo(2,3-8)-thiazolium salts and mesoionic didehydro derivatives thereof |
WO1982002044A1 (en) * | 1980-12-15 | 1982-06-24 | Corp Ethyl | Preparation of pyrrole esters |
EP0091181B1 (en) * | 1982-02-25 | 1986-12-17 | Beecham Group Plc | Aroyl pyrrolizine compounds, process for their preparation and pharmaceutical compositions containing them |
FR2539417A1 (en) * | 1983-01-13 | 1984-07-20 | Rhone Poulenc Sante | NEW PYRROLO-1, 2 HETEROCYCLES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM |
FR2557111B1 (en) * | 1983-12-21 | 1986-04-11 | Rhone Poulenc Sante | NOVEL ORTHO-CONDENSES OF PYRROLE, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM |
IL78834A (en) * | 1985-05-23 | 1992-07-15 | Smithkline Beckman Corp | 2,3-dihydro-5-(1,4-dihydropyridin-4-yl)-6-phenylimidazo(2,1-b)thiazoles and 6,7-dihydro-3-(1,4-dihydropyridin-4-yl)-2-phenyl-5h-imidazo(2,1-b)(1,3)thiazines and their use as intermediates in a process for preparing the corresponding pyridyl-substituted imidazo(2,1-b)thiazoles and 5h-imidazo(2,1-b)(1,3)thiazines |
FR2601016B1 (en) * | 1986-07-04 | 1988-10-07 | Rhone Poulenc Sante | NOVEL 1H, 3H-PYRROLO (1,2-C) THIAZOLE DERIVATIVES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2617484B1 (en) * | 1987-07-02 | 1989-10-20 | Rhone Poulenc Sante | PROCESS FOR THE PREPARATION OF ACID (PYRIDYL-3) -3 1H-3H-PYRROLO (1,2-C) THIAZOLECARBOXYLIQUE-7 DEXTROGYRE |
-
1989
- 1989-05-11 DE DE3915450A patent/DE3915450A1/en not_active Withdrawn
-
1990
- 1990-05-07 AU AU54800/90A patent/AU637098B2/en not_active Ceased
- 1990-05-09 FI FI902316A patent/FI95258C/en active IP Right Grant
- 1990-05-09 DD DD90340498A patent/DD294260A5/en unknown
- 1990-05-10 EP EP90108827A patent/EP0397175B1/en not_active Expired - Lifetime
- 1990-05-10 CA CA002016501A patent/CA2016501C/en not_active Expired - Lifetime
- 1990-05-10 ES ES90108827T patent/ES2062160T3/en not_active Expired - Lifetime
- 1990-05-10 DE DE90108827T patent/DE59003753D1/en not_active Expired - Fee Related
- 1990-05-10 AT AT90108827T patent/ATE98246T1/en not_active IP Right Cessation
- 1990-05-10 DK DK90108827.8T patent/DK0397175T3/en active
- 1990-05-10 NO NO902084A patent/NO174892C/en not_active IP Right Cessation
- 1990-05-11 KR KR1019900006713A patent/KR0173455B1/en not_active IP Right Cessation
- 1990-05-11 AR AR90316838A patent/AR246256A1/en active
- 1990-05-11 JP JP2122816A patent/JP2796876B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE3915450A1 (en) | 1990-11-15 |
FI95258B (en) | 1995-09-29 |
DD294260A5 (en) | 1991-09-26 |
EP0397175A1 (en) | 1990-11-14 |
FI95258C (en) | 1996-01-10 |
EP0397175B1 (en) | 1993-12-08 |
ES2062160T3 (en) | 1994-12-16 |
DE59003753D1 (en) | 1994-01-20 |
NO174892B (en) | 1994-04-18 |
DK0397175T3 (en) | 1994-02-14 |
FI902316A0 (en) | 1990-05-09 |
CA2016501A1 (en) | 1990-11-11 |
KR0173455B1 (en) | 1999-02-01 |
NO902084D0 (en) | 1990-05-10 |
ATE98246T1 (en) | 1993-12-15 |
NO174892C (en) | 1994-07-27 |
JPH035455A (en) | 1991-01-11 |
CA2016501C (en) | 2001-10-09 |
JP2796876B2 (en) | 1998-09-10 |
AR246256A1 (en) | 1994-07-29 |
KR900018103A (en) | 1990-12-20 |
AU5480090A (en) | 1990-11-15 |
AU637098B2 (en) | 1993-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |