NO900264L - Fremgangsmaate for fremstilling av en kombinasjon av beta-blokkerende/angiotensin ii-blokkerende antihypertensive midler. - Google Patents
Fremgangsmaate for fremstilling av en kombinasjon av beta-blokkerende/angiotensin ii-blokkerende antihypertensive midler.Info
- Publication number
- NO900264L NO900264L NO90900264A NO900264A NO900264L NO 900264 L NO900264 L NO 900264L NO 90900264 A NO90900264 A NO 90900264A NO 900264 A NO900264 A NO 900264A NO 900264 L NO900264 L NO 900264L
- Authority
- NO
- Norway
- Prior art keywords
- blocking
- angiotensin
- beta
- procedure
- preparation
- Prior art date
Links
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 229940030600 antihypertensive agent Drugs 0.000 title 1
- 239000002220 antihypertensive agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/299,709 US4916129A (en) | 1989-01-19 | 1989-01-19 | Combination β-blocking/angiotensin II blocking antihypertensives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO900264D0 NO900264D0 (no) | 1990-01-18 |
| NO900264L true NO900264L (no) | 1990-07-20 |
Family
ID=23155938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO90900264A NO900264L (no) | 1989-01-19 | 1990-01-18 | Fremgangsmaate for fremstilling av en kombinasjon av beta-blokkerende/angiotensin ii-blokkerende antihypertensive midler. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4916129A (fr) |
| EP (1) | EP0380959A1 (fr) |
| JP (1) | JPH032169A (fr) |
| KR (1) | KR920001672B1 (fr) |
| AU (1) | AU618503B2 (fr) |
| CA (1) | CA2006604A1 (fr) |
| FI (1) | FI900294A0 (fr) |
| HU (1) | HU205352B (fr) |
| IL (1) | IL93105A (fr) |
| MY (1) | MY104864A (fr) |
| NO (1) | NO900264L (fr) |
| NZ (1) | NZ232140A (fr) |
| PT (1) | PT92897A (fr) |
| ZA (1) | ZA90402B (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR940006950B1 (ko) * | 1989-05-02 | 1994-07-30 | 후지꾸라 가부시끼가이샤 | 압전형 가속도센서 및 압전형 가속도센서장치 |
| IE70593B1 (en) * | 1989-09-29 | 1996-12-11 | Eisai Co Ltd | Biphenylmethane derivative the use of it and pharmacological compositions containing same |
| CA2028925A1 (fr) * | 1989-11-06 | 1991-05-07 | Gerald R. Girard | Derives substitues de la n-(imidazolyl)alkylalanine |
| US5073566A (en) * | 1989-11-30 | 1991-12-17 | Eli Lilly And Company | Angiotensin ii antagonist 1,3-imidazoles and use thereas |
| DE122007000050I1 (de) * | 1990-02-19 | 2007-11-08 | Novartis Ag | Acylverbindungen |
| US5179113A (en) * | 1990-03-20 | 1993-01-12 | E. I. Du Pont De Nemours And Company | Treatment of central nervous disorders with imidazole compounds |
| US5210092A (en) * | 1990-09-25 | 1993-05-11 | Fujisawa Pharmaceutical Co., Ltd. | Angiotensin ii antagonizing heterocyclic derivatives |
| DE4036706A1 (de) * | 1990-11-17 | 1992-05-21 | Hoechst Ag | Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie |
| IE920540A1 (en) | 1991-02-21 | 1992-08-26 | Sankyo Co | 1-biphenylmethylimidazole derivatives, their preparation and¹their therapetuic use |
| US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
| FR2673427B1 (fr) * | 1991-03-01 | 1993-06-18 | Sanofi Elf | Derives heterocycliques diazotes n-substitues par un groupement biphenylmethyle, leur preparation, les compositions pharmaceutiques en contenant. |
| GB9110636D0 (en) * | 1991-05-16 | 1991-07-03 | Glaxo Group Ltd | Chemical compounds |
| FR2677984B1 (fr) * | 1991-06-21 | 1994-02-25 | Elf Sanofi | Derives d'imidazoline n-substitues, leur preparation, les compositions pharmaceutiques en contenant. |
| EP0599999A1 (fr) * | 1991-08-19 | 1994-06-08 | E.I. Du Pont De Nemours And Company | Derives d'imidazolinone bloquant les recepteurs d'angiotensine ii. |
| AU2494792A (en) * | 1991-08-19 | 1993-03-16 | E.I. Du Pont De Nemours And Company | Angiotensin ii receptor blocking imidazolinone derivatives |
| US5256654A (en) * | 1991-10-24 | 1993-10-26 | American Home Products Corporation | Substituted pyrrolopyrimidines, azepinopyrimidines and pyridopyrimidines useful as angiotensin II antagonists |
| US5149699A (en) * | 1991-10-24 | 1992-09-22 | American Home Products Corporation | Substituted pyridopyrimidines useful as antgiotensin II antagonists |
| US5612360A (en) * | 1992-06-03 | 1997-03-18 | Eli Lilly And Company | Angiotensin II antagonists |
| US5401851A (en) * | 1992-06-03 | 1995-03-28 | Eli Lilly And Company | Angiotensin II antagonists |
| NO304429B1 (no) * | 1992-12-17 | 1998-12-14 | Sankyo Co | Bifenylderivater, farmas°ytisk preparat og deres anvendelse for fremstilling av et medikament for behandling av hypertensjon og hjertesykdom |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| EP3241839B1 (fr) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| WO2014151206A1 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
| EA201592263A1 (ru) | 2013-06-05 | 2016-05-31 | Синерджи Фармасьютикалз, Инк. | Ультрачистые агонисты гуанилатциклазы c, способ их получения и использования |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3705907A (en) * | 1970-02-19 | 1972-12-12 | Sandoz Ltd | 4-(2-hydroxy)-3-aminopropoxy)-indole derivatives |
| JPS54148788A (en) * | 1978-05-15 | 1979-11-21 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative and its preparation |
| JPS5671073A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | Imidazole derivative |
| JPS5671074A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative |
| JPS58157768A (ja) * | 1982-03-16 | 1983-09-19 | Takeda Chem Ind Ltd | ４−クロロ−２−フエニルイミダゾ−ル−５−酢酸誘導体 |
| PT78388B (en) * | 1983-04-12 | 1986-09-15 | Smithkline Beckman Corp | Dopamine-beta-hydroxylase inhibitors |
| GB8422165D0 (en) * | 1984-09-01 | 1984-10-03 | Wellcome Found | Compounds |
| CA1334092C (fr) * | 1986-07-11 | 1995-01-24 | David John Carini | Imidazoles bloquant les recepteurs de l'angiotensine ii |
| ZA902794B (en) * | 1989-04-18 | 1991-04-24 | Duphar Int Res | New 3-n substituted carbamoyl-indole derivatives |
-
1989
- 1989-01-19 US US07/299,709 patent/US4916129A/en not_active Expired - Fee Related
- 1989-12-22 CA CA002006604A patent/CA2006604A1/fr not_active Abandoned
-
1990
- 1990-01-17 EP EP90100874A patent/EP0380959A1/fr not_active Withdrawn
- 1990-01-17 NZ NZ232140A patent/NZ232140A/en unknown
- 1990-01-18 FI FI900294A patent/FI900294A0/fi not_active Application Discontinuation
- 1990-01-18 NO NO90900264A patent/NO900264L/no unknown
- 1990-01-18 IL IL9310590A patent/IL93105A/en not_active IP Right Cessation
- 1990-01-18 JP JP2007287A patent/JPH032169A/ja active Pending
- 1990-01-18 PT PT92897A patent/PT92897A/pt not_active Application Discontinuation
- 1990-01-18 HU HU90184A patent/HU205352B/hu not_active IP Right Cessation
- 1990-01-18 KR KR1019900000556A patent/KR920001672B1/ko not_active IP Right Cessation
- 1990-01-19 MY MYPI90000092A patent/MY104864A/en unknown
- 1990-01-19 AU AU48545/90A patent/AU618503B2/en not_active Ceased
- 1990-01-19 ZA ZA90402A patent/ZA90402B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MY104864A (en) | 1994-06-30 |
| PT92897A (pt) | 1990-07-31 |
| JPH032169A (ja) | 1991-01-08 |
| US4916129A (en) | 1990-04-10 |
| AU4854590A (en) | 1990-07-26 |
| IL93105A0 (en) | 1990-11-05 |
| HU900184D0 (en) | 1990-03-28 |
| ZA90402B (en) | 1991-09-25 |
| AU618503B2 (en) | 1991-12-19 |
| KR900011739A (ko) | 1990-08-02 |
| NZ232140A (en) | 1991-06-25 |
| IL93105A (en) | 1994-02-27 |
| CA2006604A1 (fr) | 1990-07-19 |
| NO900264D0 (no) | 1990-01-18 |
| EP0380959A1 (fr) | 1990-08-08 |
| KR920001672B1 (ko) | 1992-02-22 |
| HUT53618A (en) | 1990-11-28 |
| HU205352B (en) | 1992-04-28 |
| FI900294A0 (fi) | 1990-01-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO900264L (no) | Fremgangsmaate for fremstilling av en kombinasjon av beta-blokkerende/angiotensin ii-blokkerende antihypertensive midler. | |
| NO905255L (no) | Fremgangsmaate for fremstilling av heterocyklisk substituerte acylaminotiazoler. | |
| NO900830D0 (no) | Fremgangsmaate for fremstilling av piperidinforbindelser. | |
| NO905008L (no) | Fremgangsmaate for fremstilling av heterocykliske forbindelser. | |
| NO890269D0 (no) | Fremgangsmaate for fremstilling av 1,4-disubstituerte-piperidinyl-forbindelser. | |
| NO902003L (no) | Fremgangsmaate for fremstilling av n-heteroaryl-4-quinolinaminer. | |
| NO911122D0 (no) | Fremgangsmaate for fremstilling av antihyperkolesterolemiske midler. | |
| NO885454L (no) | Fremgangsmaate for fremstilling av triklormonosilan. | |
| NO901554L (no) | Fremgangsmaate for fremstilling av dinatrium-cefodizim. | |
| NO894210L (no) | Fremgangsmaate for fremstilling av kinolyloxazol-2-oner. | |
| NO904285D0 (no) | Fremgangsmaate for fremstilling av substituerte karboksytetrahydroisokinoliner. | |
| NO892204L (no) | Fremgangsmaate for fremstilling av imidazokinoxalin-forbindelser. | |
| NO895032D0 (no) | Fremgangsmaate for fremstilling av 2-benzotiazoliner. | |
| NO890159L (no) | Fremgangsmaate for fremstilling av 1-alkyl-5-nitroimidazoler. | |
| NO903666D0 (no) | Fremgangsmaate for fremstilling av pyrrolokinolinforbindelser. | |
| NO901067D0 (no) | Fremgangsmaate for fremstilling av tiofener. | |
| NO904060L (no) | Fremgangsmaate for fremstilling av substituerte dibenzofuraner. | |
| NO895040L (no) | Fremgangsmaate for fremstilling av polyhydroxybenzyloxypropanolaminer. | |
| NO904535L (no) | Fremgangsmaate for fremstilling av fenoksy-heterocykliske forbindelser. | |
| NO900969L (no) | Fremgangsmaate for fremstilling av n-allymetatrifluormetylanilin. | |
| NO904070L (no) | Fremgangsmaate for fremstilling av alkanfenoner. | |
| DK12887A (da) | Fremgangsmaade til fremstilling af n,n'-diacetylethylendiamin | |
| ATE91413T1 (de) | Hypotensiver wirkstoff. | |
| NO890819L (no) | Fremgangsmaate for fremstilling av hydroksybenzaldehyder. | |
| NO880435L (no) | Fremgangsmaate for inhibering av frigivelsen av histamin. |