NO891260D0 - Fremgangsmaate for fremstilling av 4-aryl-4-piperidin (eller pyrrolidin eller hexahydroazepin) carbinoler. - Google Patents
Fremgangsmaate for fremstilling av 4-aryl-4-piperidin (eller pyrrolidin eller hexahydroazepin) carbinoler.Info
- Publication number
- NO891260D0 NO891260D0 NO891260A NO891260A NO891260D0 NO 891260 D0 NO891260 D0 NO 891260D0 NO 891260 A NO891260 A NO 891260A NO 891260 A NO891260 A NO 891260A NO 891260 D0 NO891260 D0 NO 891260D0
- Authority
- NO
- Norway
- Prior art keywords
- carbinols
- aryl
- hexahydroazepine
- pyrrolidine
- piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17435688A | 1988-03-28 | 1988-03-28 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO891260D0 true NO891260D0 (no) | 1989-03-22 |
| NO891260L NO891260L (no) | 1989-09-29 |
Family
ID=22635870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO89891260A NO891260L (no) | 1988-03-28 | 1989-03-22 | Fremgangsmaate for fremstilling av 4-aryl-4-piperidin (eller pyrrolidin eller hexahydroazepin) carbinoler. |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0337167B1 (no) |
| JP (1) | JP2907860B2 (no) |
| KR (1) | KR0140891B1 (no) |
| AT (1) | ATE109465T1 (no) |
| AU (1) | AU623637B2 (no) |
| CA (1) | CA1337418C (no) |
| DE (1) | DE68917185T2 (no) |
| DK (1) | DK145689A (no) |
| ES (1) | ES2056990T3 (no) |
| FI (1) | FI94240C (no) |
| HU (1) | HU213671B (no) |
| IE (1) | IE65811B1 (no) |
| IL (1) | IL89746A0 (no) |
| MY (1) | MY103990A (no) |
| NO (1) | NO891260L (no) |
| NZ (1) | NZ228479A (no) |
| PT (1) | PT90127B (no) |
| RU (1) | RU1836346C (no) |
| ZA (1) | ZA892171B (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2047389C (en) * | 1990-07-24 | 2002-04-23 | James R. Mccarthy | Substituted piperidines and their use as inhibitors of cholesterol synthesis |
| DE4112353A1 (de) * | 1991-04-16 | 1992-10-22 | Basf Ag | 1,3,4-trisubstituierte piperidin-derivate, ihre herstellung und verwendung |
| ATE188472T1 (de) * | 1992-10-28 | 2000-01-15 | Merck Sharp & Dohme | 4-arylmethyloxymethyl piperidine als tachykinin antagonisten |
| WO2002046156A2 (en) * | 2000-12-06 | 2002-06-13 | Sepracor, Inc. | 4,4-disubstituted piperidines for use as dopamine, serotonin and norepinephrine ligands |
| ATE332688T1 (de) * | 2001-10-16 | 2006-08-15 | Endo Pharmaceuticals Inc | Verwendung von carbinolen zur behandlung von neuropathischer funktionsstörung |
| US20070249607A1 (en) | 2006-04-17 | 2007-10-25 | Bristol-Myers Squibb Company | Nk-1 and serotonin transporter inhibitors |
| US8071778B2 (en) | 2006-07-27 | 2011-12-06 | Bristol-Myers Squibb Company | Substituted heterocyclic ethers and their use in CNS disorders |
| US8026257B2 (en) | 2007-07-11 | 2011-09-27 | Bristol-Myers Squibb Company | Substituted heterocyclic ethers and their use in CNS disorders |
| US11702408B2 (en) | 2017-02-17 | 2023-07-18 | Trevena, Inc. | 5-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same |
| EP3582783B1 (en) * | 2017-02-17 | 2023-06-07 | Trevena, Inc. | 7-membered aza-heterocyclic containing delta-opioid receptor modulating compounds, methods of using and making the same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB888657A (en) * | 1958-07-14 | 1962-01-31 | J F Macfarlan & Co Ltd | Piperidine carbinols |
| US3080372A (en) * | 1960-03-25 | 1963-03-05 | Res Lab Dr C Janssen | 1-aroylalkyl-4-arylpiperidine derivatives |
| BE775611A (fr) * | 1970-11-24 | 1972-03-16 | Synthelabo | Derives de la (diphenyl-3,3 propyl-1)-1 piperidine, leur preparation etles medicaments qui en contiennent |
| US4284635A (en) * | 1978-11-29 | 1981-08-18 | Eli Lilly And Company | Analgesic 1,2,4,5-tetra-alkyl-4-arylpiperidines |
| US4485109A (en) * | 1982-05-07 | 1984-11-27 | E. I. Du Pont De Nemours And Company | 4-Aryl-4-piperidinecarbinols |
| ZA833253B (en) * | 1982-05-07 | 1984-12-24 | Du Pont | 4-aryl-4-piperidinecarbinols |
-
1989
- 1989-02-22 CA CA000591753A patent/CA1337418C/en not_active Expired - Lifetime
- 1989-03-22 AT AT89105083T patent/ATE109465T1/de not_active IP Right Cessation
- 1989-03-22 ES ES89105083T patent/ES2056990T3/es not_active Expired - Lifetime
- 1989-03-22 ZA ZA892171A patent/ZA892171B/xx unknown
- 1989-03-22 NO NO89891260A patent/NO891260L/no unknown
- 1989-03-22 DK DK145689A patent/DK145689A/da not_active Application Discontinuation
- 1989-03-22 DE DE68917185T patent/DE68917185T2/de not_active Expired - Lifetime
- 1989-03-22 EP EP89105083A patent/EP0337167B1/en not_active Expired - Lifetime
- 1989-03-23 IE IE91389A patent/IE65811B1/en not_active IP Right Cessation
- 1989-03-23 NZ NZ228479A patent/NZ228479A/en unknown
- 1989-03-27 RU SU894613736A patent/RU1836346C/ru active
- 1989-03-27 IL IL89746A patent/IL89746A0/xx not_active IP Right Cessation
- 1989-03-27 MY MYPI89000381A patent/MY103990A/en unknown
- 1989-03-28 PT PT90127A patent/PT90127B/pt not_active IP Right Cessation
- 1989-03-28 FI FI891473A patent/FI94240C/fi not_active IP Right Cessation
- 1989-03-28 HU HU891532A patent/HU213671B/hu not_active IP Right Cessation
- 1989-03-28 AU AU31717/89A patent/AU623637B2/en not_active Ceased
- 1989-03-28 JP JP1074129A patent/JP2907860B2/ja not_active Expired - Lifetime
- 1989-03-28 KR KR1019890003866A patent/KR0140891B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE65811B1 (en) | 1995-11-15 |
| HU213671B (en) | 1997-09-29 |
| AU3171789A (en) | 1989-09-28 |
| KR890014475A (ko) | 1989-10-23 |
| EP0337167A1 (en) | 1989-10-18 |
| FI891473A0 (fi) | 1989-03-28 |
| AU623637B2 (en) | 1992-05-21 |
| DE68917185D1 (de) | 1994-09-08 |
| HUT50787A (en) | 1990-03-28 |
| RU1836346C (ru) | 1993-08-23 |
| DE68917185T2 (de) | 1995-01-05 |
| IE890913L (en) | 1989-09-28 |
| FI94240B (fi) | 1995-04-28 |
| MY103990A (en) | 1993-10-30 |
| FI94240C (fi) | 1995-08-10 |
| FI891473A (fi) | 1989-09-29 |
| PT90127A (pt) | 1989-11-10 |
| KR0140891B1 (ko) | 1998-06-01 |
| ES2056990T3 (es) | 1994-10-16 |
| IL89746A0 (en) | 1989-09-28 |
| DK145689D0 (da) | 1989-03-22 |
| NZ228479A (en) | 1991-12-23 |
| JPH0249766A (ja) | 1990-02-20 |
| JP2907860B2 (ja) | 1999-06-21 |
| EP0337167B1 (en) | 1994-08-03 |
| DK145689A (da) | 1989-09-29 |
| NO891260L (no) | 1989-09-29 |
| PT90127B (pt) | 1994-06-30 |
| ATE109465T1 (de) | 1994-08-15 |
| CA1337418C (en) | 1995-10-24 |
| ZA892171B (en) | 1990-11-28 |
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