NO873785L - Fremgangsmaate ved fremstilling av eddiksyreesteren til haloperidol. - Google Patents

Fremgangsmaate ved fremstilling av eddiksyreesteren til haloperidol.

Info

Publication number
NO873785L
NO873785L NO873785A NO873785A NO873785L NO 873785 L NO873785 L NO 873785L NO 873785 A NO873785 A NO 873785A NO 873785 A NO873785 A NO 873785A NO 873785 L NO873785 L NO 873785L
Authority
NO
Norway
Prior art keywords
haloperidol
acetic acid
estate
preparing
procedure
Prior art date
Application number
NO873785A
Other languages
English (en)
Other versions
NO169893C (no
NO169893B (no
NO873785D0 (no
Inventor
Jens Kristian Perregaard
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of NO873785D0 publication Critical patent/NO873785D0/no
Publication of NO873785L publication Critical patent/NO873785L/no
Publication of NO169893B publication Critical patent/NO169893B/no
Publication of NO169893C publication Critical patent/NO169893C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
NO873785A 1986-09-11 1987-09-10 Analogifremgangsmaate ved fremstilling av eddiksyreesterenav haloperidol NO169893C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868621892A GB8621892D0 (en) 1986-09-11 1986-09-11 Organic compound

Publications (4)

Publication Number Publication Date
NO873785D0 NO873785D0 (no) 1987-09-10
NO873785L true NO873785L (no) 1988-03-14
NO169893B NO169893B (no) 1992-05-11
NO169893C NO169893C (no) 1992-08-19

Family

ID=10604021

Family Applications (1)

Application Number Title Priority Date Filing Date
NO873785A NO169893C (no) 1986-09-11 1987-09-10 Analogifremgangsmaate ved fremstilling av eddiksyreesterenav haloperidol

Country Status (16)

Country Link
US (1) US4855307A (no)
EP (1) EP0260070B1 (no)
JP (1) JPS6377857A (no)
AT (1) ATE92917T1 (no)
AU (1) AU591334B2 (no)
DE (1) DE3786966T2 (no)
DK (1) DK166320C (no)
ES (1) ES2058120T3 (no)
FI (1) FI88155C (no)
GB (1) GB8621892D0 (no)
IE (1) IE60902B1 (no)
IL (1) IL83819A (no)
NO (1) NO169893C (no)
NZ (1) NZ221711A (no)
PT (1) PT85678B (no)
ZA (1) ZA876819B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3742580C1 (de) * 1987-12-16 1989-05-11 Schaper & Bruemmer Gmbh Verwendung des alpha,alpha-Diphenyl-alpha-(3-carboxy-propionyloxy)-essigsaeure-4-(N-methylpiperidyl)-esters zur Behandlung hypertoner Funktionszustaende im Bereich der Harnblase
US5776963A (en) 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
DK238190D0 (da) * 1990-10-03 1990-10-03 Lundbeck & Co As H Depotderivater
KR20080059687A (ko) 2000-03-06 2008-06-30 아카디아 파마슈티칼스 인코포레이티드 세로토닌 관련 질병의 치료에 사용되는 아자시클릭 화합물
EP1787984B1 (en) * 2000-03-06 2016-10-19 Acadia Pharmaceuticals Inc. Azacyclic compounds for use in the treatment of serotonin related diseases
WO2003057698A2 (en) 2001-12-28 2003-07-17 Acadia Pharmaceuticals, Inc. Spiroazacyclic compounds as monoamine receptor modulators
US7538222B2 (en) 2002-06-24 2009-05-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
NZ537522A (en) 2002-06-24 2006-07-28 Acadia Pharm Inc N-substituted piperidine derivatives as serotonin receptor agents
US7253186B2 (en) 2002-06-24 2007-08-07 Carl-Magnus Andersson N-substituted piperidine derivatives as serotonin receptor agents
MXPA05007568A (es) 2003-01-16 2005-09-21 Acadia Pharm Inc Agonistas inversos del receptor selectivo de serotonina 2a/2c como terapeuticos para enfermedades neurodegenerativas.
US7820695B2 (en) 2004-05-21 2010-10-26 Acadia Pharmaceuticals, Inc. Selective serotonin receptor inverse agonists as therapeutics for disease
US20050261278A1 (en) 2004-05-21 2005-11-24 Weiner David M Selective serotonin receptor inverse agonists as therapeutics for disease
US7790899B2 (en) 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
PL2289879T3 (pl) 2004-09-27 2015-05-29 Acadia Pharm Inc Synteza formy krystalicznej soli winianowej n-(4-fluorobenzylo)-n-(1-metylopiperydyn-4-ylo)-n'-(4-(2-metylopropyloksy)fenylometylo)karbamidu
WO2008116024A2 (en) 2007-03-19 2008-09-25 Acadia Pharmaceuticals Inc. Combinations of 5-ht2a inverse agonists and antagonists with antipsychotics
PT3325444T (pt) 2015-07-20 2021-09-22 Acadia Pharm Inc Métodos para preparar n-(4-fluorobenzil)-n-(1-metilpiperidina-4-il)-n'-(4-(2-metilpropiloxi)fenilmetil)carbamida e o seu sal de tartarato e forma polimórfica c
WO2017165635A1 (en) 2016-03-25 2017-09-28 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome p450 modulators
US10953000B2 (en) 2016-03-25 2021-03-23 Acadia Pharmaceuticals Inc. Combination of pimavanserin and cytochrome P450 modulators
WO2018118626A1 (en) 2016-12-20 2018-06-28 Acadia Pharmaceuticals Inc. Pimavanserin alone or in combination for use in the treatment of alzheimer's disease psychosis
EP3615028A1 (en) 2017-04-28 2020-03-04 Acadia Pharmaceuticals Inc. Pimavanserin for treating impulse control disorder
WO2019046167A1 (en) 2017-08-30 2019-03-07 Acadia Pharmaceuticals Inc. PIMAVANSERIN FORMULATIONS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB895309A (en) * 1959-11-18 1962-05-02 Res Lab Dr C Janssen Nv Pyrrolidine and piperidine derivatives
US3408356A (en) * 1965-08-31 1968-10-29 Squibb & Sons Inc Long chain esters of 4'-fluoro-4-[4-hydroxy-4-(alpha, alpha, alpha-trifluorotolyl)piperi-dino]butyrophenone and the like
DE1695194A1 (de) * 1966-07-11 1971-03-18 Hoffmann La Roche Verfahren zur Herstellung von Piperidinderivaten
US4070473A (en) * 1973-01-26 1978-01-24 Ab Ferrosan Piperidino-butyrophenones
JPS568318A (en) * 1979-06-28 1981-01-28 Janssen Pharmaceutica Nv Non oral long acting composition of haloperidol and bromperidol derivative

Also Published As

Publication number Publication date
ES2058120T3 (es) 1994-11-01
IL83819A (en) 1992-02-16
FI88155B (fi) 1992-12-31
ATE92917T1 (de) 1993-08-15
JPS6377857A (ja) 1988-04-08
DE3786966D1 (de) 1993-09-16
EP0260070B1 (en) 1993-08-11
PT85678B (pt) 1990-05-31
DK166320B (da) 1993-04-05
FI873924A0 (fi) 1987-09-10
US4855307A (en) 1989-08-08
NO169893C (no) 1992-08-19
FI873924A (fi) 1988-03-12
IE60902B1 (en) 1994-08-24
AU7823287A (en) 1988-03-17
IE872366L (en) 1988-03-11
AU591334B2 (en) 1989-11-30
DK479587D0 (da) 1987-09-11
DE3786966T2 (de) 1994-03-17
DK166320C (da) 1993-08-23
PT85678A (en) 1987-10-01
NO169893B (no) 1992-05-11
IL83819A0 (en) 1988-02-29
DK479587A (da) 1988-03-12
EP0260070A1 (en) 1988-03-16
NO873785D0 (no) 1987-09-10
ZA876819B (en) 1988-06-29
NZ221711A (en) 1989-11-28
FI88155C (fi) 1993-04-13
GB8621892D0 (en) 1986-10-15

Similar Documents

Publication Publication Date Title
NO873785L (no) Fremgangsmaate ved fremstilling av eddiksyreesteren til haloperidol.
FI20000507A (fi) (+)-1-(3-dimetyyliaminopropyyli)-1-(4'-fluorifenyyli)-1,3-dihydroisobentsofuraani-5-karbonitriili ja sitä sisältävä farmaseuttinen koostumus
PT89061A (pt) Processo para a estabilizacao de acido 2-(n-((s)-1-etoxicarbonil-3-fenilpropil)-l-alanil)-(1s,3s,5s)-2-azabiciclo-(3.3,0)-octano-3-carboxilico(ramipril)e de composicoes farmaceuticas estabilizadas que o contem
DK249680A (da) Fremgangsmaade til fremstilling af 4-substituerede 3-hydroxy-3-pyrrolin-2,5-dioner
ES2074846T3 (es) Nuevas naftil-etil-ureas y naftil-etil-tioureas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen.
ES2109735T3 (es) Composiciones adhesivas activables por humedad.
EP0257485A3 (de) Kombination von positiv inotrop wirkenden Dihydropyridinen mit ACE-Hemmern, sowie ihre Verwendung in Arzneimitteln
DE69122866D1 (de) Herstellung von substituierten piperidinen
ATE51617T1 (de) Verfahren zur herstellung von 4-phenyl-pyrrolderivaten.
DK287881A (da) G substituerede oxocarboxylsyrer fremgangsmaade til fremstillin deraf og anvendelse deraf
ATE287289T1 (de) Rückfettende ester auf basis von capryl-alkohol und isostearinsäure
ATE92469T1 (de) Neue alpha-aminocarbonsaeure-derivate, ihre herstellung und verwendung.
ATE69795T1 (de) Verfahren zur herstellung von ethylenischen carbonylverbindungen.
DE3775833D1 (de) Methylierte chitosane und ihre verwendung bei der herstellung von pharmazeutischen zusammensetzungen.
ATE4117T1 (de) Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel.
ATE124039T1 (de) Durch azetidine substituierte derivate von pyridon-carboxylsäure, ihre herstellung und verwendung als arzneimittel.
ATE90095T1 (de) Optisch aktive produkte von 20,21dinoreburnamenin-derivaten,verfahren zur herstellung, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammenstellungen.
DE3770287D1 (de) Neue n-glycosylamidderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel.
ATE70060T1 (de) Neue tetrahydro-benzothiazole, ihre herstellung und verwendung.
DE69715733D1 (de) Verfahren zur Herstellung von 5-Brom-2-Fluorbenzolboronsäure
ATE79612T1 (de) Verfahren zur herstellung von alpha-(alkylphenyl)-4-(hydroxydiphenylmethyl)-1 piperidinbutanol.
PT87071A (pt) Calciumlactat-glycerin-addukt verfahren zu seiner herstellung sowie seine verwendung
ES2045070T3 (es) Procedimiento para la fabricacion de esteres asimetricos de dihidropiridinas.
NO911237L (no) Fremgangsmaate for fremstilling av hydroxymethyl-indolizidiner og kinolizidiner
DE59204444D1 (de) Verfahren zur herstellung von epoxygruppen aufweisenden organosiliciumverbindungen.