NO871912D0 - Dyrecelletransformant, fremgangsmaate for fremstilling av transformanten og fremgangsmaate for fremstilling av det oenskede gen-produkt under anvendelse av transformanten. - Google Patents

Dyrecelletransformant, fremgangsmaate for fremstilling av transformanten og fremgangsmaate for fremstilling av det oenskede gen-produkt under anvendelse av transformanten.

Info

Publication number
NO871912D0
NO871912D0 NO871912A NO871912A NO871912D0 NO 871912 D0 NO871912 D0 NO 871912D0 NO 871912 A NO871912 A NO 871912A NO 871912 A NO871912 A NO 871912A NO 871912 D0 NO871912 D0 NO 871912D0
Authority
NO
Norway
Prior art keywords
transformer
procedure
manufacturing
gene product
animal cell
Prior art date
Application number
NO871912A
Other languages
English (en)
Other versions
NO871912L (no
Inventor
Noboru Tomioka
Fumio Omae
Eriko Mine
Tomoko Ishii
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of NO871912D0 publication Critical patent/NO871912D0/no
Publication of NO871912L publication Critical patent/NO871912L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
NO871912A 1986-05-10 1987-05-08 Fremgangsmaate for fremstilling av en animalsk celletransformant. NO871912L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61105824A JP2585532B2 (ja) 1986-05-10 1986-05-10 動物細胞の形質転換体及びそれを得る方法並びにその形質転換体を用いてｔ−ＰＡを生産する方法

Publications (2)

Publication Number Publication Date
NO871912D0 true NO871912D0 (no) 1987-05-08
NO871912L NO871912L (no) 1987-11-11

Family

ID=14417809

Family Applications (1)

Application Number Title Priority Date Filing Date
NO871912A NO871912L (no) 1986-05-10 1987-05-08 Fremgangsmaate for fremstilling av en animalsk celletransformant.

Country Status (9)

Country Link
US (1) US5219738A (no)
EP (1) EP0246049B1 (no)
JP (1) JP2585532B2 (no)
AU (1) AU599977B2 (no)
DE (1) DE3787044T2 (no)
DK (1) DK235587A (no)
FI (1) FI872013A (no)
NO (1) NO871912L (no)
ZA (1) ZA873211B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5550036A (en) * 1986-04-09 1996-08-27 Eli Lilly And Company Method for co-amplification of human protein C genes in human cells
EP0319206A3 (en) * 1987-11-30 1990-04-18 Berlex Laboratories, Inc. Gene amplification
ATE129289T1 (de) * 1988-12-08 1995-11-15 Abbott Lab Verfahren zur induzierbaren genexpression unter verwendung eines dhfr-gens.
BRPI1008762B8 (pt) 2009-02-27 2021-05-25 Novartis Ag métodos para seleção de células de mamífero expressando uma proteína heteróloga, para produzir um produto de interesse e uso de um meio de cultura seletivo
DK3027646T3 (en) 2013-07-31 2018-09-24 Novartis Ag New selection vectors and methods for selecting eukaryotic host cells
KR102288857B1 (ko) 2013-12-20 2021-08-11 노파르티스 아게 신규한 진핵 세포 및 관심 생성물의 재조합 발현 방법
DK3083677T3 (da) 2013-12-20 2019-11-25 Novartis Ag Hidtil ukendte eukaryote celler og fremgangsmåder til rekombinant ekspression af et produkt af interesse
JP6245299B2 (ja) * 2016-04-27 2017-12-13 バクスアルタ ゲーエムベーハー 組換え安定細胞クローン、その産生およびその使用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE223230C (no) *
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
IE56716B1 (en) * 1983-01-19 1991-11-20 Genentech Inc Method for producing human tpa and expression vectors therefor
US4713339A (en) * 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
AU2353384A (en) * 1983-01-19 1984-07-26 Genentech Inc. Amplification in eukaryotic host cells
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
IL71691A (en) * 1984-04-27 1991-04-15 Yeda Res & Dev Production of interferon-ypsilon
GB2183662B (en) * 1985-04-01 1989-01-25 Celltech Ltd Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
JPH0714341B2 (ja) * 1985-11-20 1995-02-22 鐘淵化学工業株式会社 蛋白質の高生産株の取得方法

Also Published As

Publication number Publication date
DE3787044T2 (de) 1993-12-09
NO871912L (no) 1987-11-11
FI872013A0 (fi) 1987-05-06
JPS62262988A (ja) 1987-11-16
ZA873211B (en) 1987-10-28
FI872013A (fi) 1987-11-11
EP0246049A1 (en) 1987-11-19
DK235587D0 (da) 1987-05-08
DK235587A (da) 1987-11-11
EP0246049B1 (en) 1993-08-18
US5219738A (en) 1993-06-15
JP2585532B2 (ja) 1997-02-26
AU7265087A (en) 1987-11-12
AU599977B2 (en) 1990-08-02
DE3787044D1 (de) 1993-09-23

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