FI872013A - Djurcelltransformant, foerfarande foer framstaellning av transformanten och foerfarande foer framstaellning av oenskad fraemmande genprodukt genom att anvaenda transformanten. - Google Patents

Djurcelltransformant, foerfarande foer framstaellning av transformanten och foerfarande foer framstaellning av oenskad fraemmande genprodukt genom att anvaenda transformanten. Download PDF

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Publication number
FI872013A
FI872013A FI872013A FI872013A FI872013A FI 872013 A FI872013 A FI 872013A FI 872013 A FI872013 A FI 872013A FI 872013 A FI872013 A FI 872013A FI 872013 A FI872013 A FI 872013A
Authority
FI
Finland
Prior art keywords
transformanten
foerfarande foer
foer framstaellning
oenskad
fraemmande
Prior art date
Application number
FI872013A
Other languages
English (en)
Other versions
FI872013A0 (fi
Inventor
Noboru Tomioka
Fumio Omae
Eriko Mine
Tomoko Ishii
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of FI872013A0 publication Critical patent/FI872013A0/fi
Publication of FI872013A publication Critical patent/FI872013A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI872013A 1986-05-10 1987-05-06 Djurcelltransformant, foerfarande foer framstaellning av transformanten och foerfarande foer framstaellning av oenskad fraemmande genprodukt genom att anvaenda transformanten. FI872013A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61105824A JP2585532B2 (ja) 1986-05-10 1986-05-10 動物細胞の形質転換体及びそれを得る方法並びにその形質転換体を用いてｔ−ＰＡを生産する方法

Publications (2)

Publication Number Publication Date
FI872013A0 FI872013A0 (fi) 1987-05-06
FI872013A true FI872013A (fi) 1987-11-11

Family

ID=14417809

Family Applications (1)

Application Number Title Priority Date Filing Date
FI872013A FI872013A (fi) 1986-05-10 1987-05-06 Djurcelltransformant, foerfarande foer framstaellning av transformanten och foerfarande foer framstaellning av oenskad fraemmande genprodukt genom att anvaenda transformanten.

Country Status (9)

Country Link
US (1) US5219738A (fi)
EP (1) EP0246049B1 (fi)
JP (1) JP2585532B2 (fi)
AU (1) AU599977B2 (fi)
DE (1) DE3787044T2 (fi)
DK (1) DK235587A (fi)
FI (1) FI872013A (fi)
NO (1) NO871912L (fi)
ZA (1) ZA873211B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5550036A (en) * 1986-04-09 1996-08-27 Eli Lilly And Company Method for co-amplification of human protein C genes in human cells
EP0319206A3 (en) * 1987-11-30 1990-04-18 Berlex Laboratories, Inc. Gene amplification
DE68924605T2 (de) * 1988-12-08 1996-05-15 Abbott Lab Verfahren zur induzierbaren genexpression unter verwendung eines dhfr-gens.
CA2753813C (en) 2009-02-27 2018-12-11 Novartis Ag Methods for selecting eukaryotic cells expressing a heterologous protein
LT3412684T (lt) 2013-07-31 2022-07-11 Novartis Ag Nauji atrankos vektoriai ir eukariotinių ląstelių šeimininkių atrankos metodai
RU2712507C2 (ru) 2013-12-20 2020-01-29 Новартис Аг Новые эукариотические клетки и способы их получения для рекомбинантной экспрессии представляющего интерес продукта
BR112016013443B1 (pt) 2013-12-20 2022-11-29 Novartis Ag Métodos para produzir de forma recombinante um produto de interesse, para produção de uma célula hospedeira eucariótica para produzir de forma recombinante um produto de interesse, e para analisar as células eucarióticas quanto à sua adequabilidade como células hospedeiras para expressão recombinante de um produto de interesse
JP6245299B2 (ja) * 2016-04-27 2017-12-13 バクスアルタ ゲーエムベーハー 組換え安定細胞クローン、その産生およびその使用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE223230C (fi) *
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
AR241654A1 (es) * 1982-05-05 1992-10-30 Genentech Inc Procedimiento para producir activador de plasminogeno de tejido humano.
IE56716B1 (en) * 1983-01-19 1991-11-20 Genentech Inc Method for producing human tpa and expression vectors therefor
US4713339A (en) * 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
AU2353384A (en) * 1983-01-19 1984-07-26 Genentech Inc. Amplification in eukaryotic host cells
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
IL71691A (en) * 1984-04-27 1991-04-15 Yeda Res & Dev Production of interferon-ypsilon
WO1986005807A1 (en) * 1985-04-01 1986-10-09 Celltech Limited Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same
JPH0714341B2 (ja) * 1985-11-20 1995-02-22 鐘淵化学工業株式会社 蛋白質の高生産株の取得方法

Also Published As

Publication number Publication date
DK235587A (da) 1987-11-11
NO871912L (no) 1987-11-11
EP0246049A1 (en) 1987-11-19
DE3787044D1 (de) 1993-09-23
AU7265087A (en) 1987-11-12
ZA873211B (en) 1987-10-28
DE3787044T2 (de) 1993-12-09
JPS62262988A (ja) 1987-11-16
AU599977B2 (en) 1990-08-02
FI872013A0 (fi) 1987-05-06
DK235587D0 (da) 1987-05-08
EP0246049B1 (en) 1993-08-18
NO871912D0 (no) 1987-05-08
US5219738A (en) 1993-06-15
JP2585532B2 (ja) 1997-02-26

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Owner name: MITSUI TOATSU CHEMICALS, INCORPORATED